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Results for “Advanced Non-Central Nervous System (CNS) Malignancies”

116 trials

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Showing 20 of 116 results

Early research (Phase 1)Study completedNCT00006221
What this trial is testing

BMS-247550 in Treating Patients With Advanced Cancers

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Ended earlyNCT05500508
What this trial is testing

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Who this might be right for
CancerSolid TumorSolid Carcinoma+17 more
Aminex Therapeutics, Inc. 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07343479
What this trial is testing

Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)EGFR Gene MutationsBrain Metastasis
Zhejiang Cancer Hospital 45
Early research (Phase 1)Study completedNCT00646139
What this trial is testing

KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment

Who this might be right for
LymphomaLymphoproliferative DisorderSmall Intestine Cancer+1 more
Roswell Park Cancer Institute 7
Early research (Phase 1)Ended earlyNCT02244112
What this trial is testing

Oprozomib to Assess Food Effect, Drug-Drug Interaction With Midazolam, and Safety and Tolerability in Patients With Advanced Malignancies

Who this might be right for
Advanced Non-Central Nervous System (CNS) Malignancies
Amgen 43
Not applicableLooking for participantsNCT06643000
What this trial is testing

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal MetastasisEGFR Gene Mutation
Henan Cancer Hospital 60
Testing effectiveness (Phase 2)UnknownNCT00663689
What this trial is testing

Efficacy of Erlotinib for Brain Metastasis of Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung CancerBrain Metastases
Guangdong Provincial People's Hospital 45
Early research (Phase 1)Study completedNCT04095273
What this trial is testing

Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

Who this might be right for
Advanced Solid Tumors
Bayer 56
Early research (Phase 1)Study completedNCT07620951
What this trial is testing

Material Balance of [14C]Zorifertinib in Healthy Adult Male Participants in China

Who this might be right for
EGFR Mutant Advanced Non-small Cell Lung CancerCentral Nervous System (CNS) Metastases
Alpha Biopharma (Jiangsu) Co., Ltd. 6
Testing effectiveness (Phase 2)UnknownNCT04180501
What this trial is testing

SRS Sequential Sindilimab in Brain Metastasis of NSLSC

Who this might be right for
NSCLC Stage IVBrain MetastasesSRS+1 more
Xiaorong Dong 25
Testing effectiveness (Phase 2)Study completedNCT00744900
What this trial is testing

Pemetrexed Plus Cisplatin for Brain Metastasis of Advanced Non - Small Cell Lung Cancer (NSCLC)

Who this might be right for
Lung Cancer
University Hospital, Brest 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Ended earlyNCT03952325
What this trial is testing

Tesetaxel Plus 3 Different PD-(L)1 Inhibitors in Patients With Triple-Negative MBC and Tesetaxel Monotherapy in Patients With HER2-Negative MBC

Who this might be right for
Breast Cancer
Odonate Therapeutics, Inc. 294
Early research (Phase 1)Study completedNCT00004002
What this trial is testing

PS-341 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
NYU Langone Health
Early research (Phase 1)Study completedNCT00049296
What this trial is testing

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Case Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)UnknownNCT04675008
What this trial is testing

Central Nervous System(CNS) Efficacy of Dacomitinib

Who this might be right for
Non Small Cell Lung CancerBrain Metastases
Samsung Medical Center 30
Early research (Phase 1)Study completedNCT01639911
What this trial is testing

Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

Who this might be right for
Malignant Neoplasm of BreastCNS MalignancyMalignant Neoplasm of Gastrointestinal Tract+4 more
University of Illinois at Chicago 28
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
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