Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Non-Central Nervous System (CNS) Malignancies”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 16 of 0 results

Early research (Phase 1)Looking for participantsNCT06253871
What this trial is testing

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Who this might be right for
HER2 Mutation-Related TumorsHER2HER2-positive Breast Cancer+10 more
Iambic Therapeutics, Inc 383
Early research (Phase 1)Ended earlyNCT02134067
What this trial is testing

Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Taiho Oncology, Inc. 30
Large-scale testing (Phase 3)UnknownNCT01158170
What this trial is testing

Prophylactic Cranial Irradiation in Erlotinib/Gefitinib-responders With Non-small Cell Lung Cancer (NSCLC) (RT1001)

Who this might be right for
Non-small Cell Lung Cancer
Zhejiang Cancer Hospital 200
Early research (Phase 1)Ended earlyNCT05241873
What this trial is testing

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Who this might be right for
Lung Neoplasm MalignantCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+17 more
Blueprint Medicines Corporation 103
Not applicableLooking for participantsNCT07143045
What this trial is testing

A Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) Metastases

Who this might be right for
EGFR Mutant Advanced Non-small Cell Lung CancerCentral Nervous System (CNS) Metastases
Alpha Biopharma (Jiangsu) Co., Ltd. 800
Early research (Phase 1)Study completedNCT00313599
What this trial is testing

Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors

Who this might be right for
Bladder CancerBrain and Central Nervous System TumorsBreast Cancer+6 more
University of California, San Francisco 28
Testing effectiveness (Phase 2)Study completedNCT00070096
What this trial is testing

Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorOvarian Cancer+1 more
Memorial Sloan Kettering Cancer Center 29
Not applicableWithdrawnNCT00499291
What this trial is testing

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors

Who this might be right for
Cancer
Eastern Cooperative Oncology Group
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06319950
What this trial is testing

High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases

Who this might be right for
Lung Cancer, Nonsmall Cell
Taizhou Hospital 255
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Early research (Phase 1)Ended earlyNCT02187822
What this trial is testing

Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases

Who this might be right for
Brain MetastasesGeneralized Malignancy, PrimaryBrain Lesions
H. Lee Moffitt Cancer Center and Research Institute 15
Large-scale testing (Phase 3)Active Not RecruitingNCT04674683
What this trial is testing

Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma

Who this might be right for
Unresectable or Metastatic MelanomaProgressive Brain Metastasis
HUYABIO International, LLC. 450
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Active Not RecruitingNCT04250545
What this trial is testing

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal NeoplasmMetastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the Brain+4 more
National Cancer Institute (NCI) 22
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo