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Results for “Advanced Parkinson Disease”

279 trials

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Showing 20 of 279 results

Not applicableNot Yet RecruitingNCT06284629
What this trial is testing

Enhancing Referral Decision-making for Advanced Treatment in Parkinson's Disease Through Objective Measurements and Patient Reported Outcomes.

Who this might be right for
Parkinson Disease
Rigshospitalet, Denmark 90
Not applicableActive Not RecruitingNCT05916157
What this trial is testing

An Observational Study of Subcutaneous Infusion of ABBV-951 to Assess Change in Disease Activity and Adverse Events In Adult Japanese Participants With Advanced Parkinson's Disease

Who this might be right for
Parkinson's Disease (PD)
AbbVie 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT06483334
What this trial is testing

Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Merck Sharp & Dohme LLC 38
Early research (Phase 1)Study completedNCT05017012
What this trial is testing

Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

Who this might be right for
Advanced or Metastatic Solid Tumors
Merck Sharp & Dohme LLC 142
Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Very early researchNot Yet RecruitingNCT07685444
What this trial is testing

A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of Intracerebral Injection of LY-N001 Injection for the Treatment of Moderate to Advanced Parkinson's Disease With GBA1 Mutations

Who this might be right for
Parkinson's Disease (PD)
Lingyi Biotech Co., Ltd. 18
Post-approval studies (Phase 4)Looking for participantsNCT06316232
What this trial is testing

DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease

Who this might be right for
Freezing of GaitParkinson Disease
IRCCS Istituto delle Scienze Neurologiche di Bologna 20
Not applicableNot Yet RecruitingNCT06559098
What this trial is testing

Vibrotactile Coordinated Reset (vCR) for the Treatment of Advanced Parkinson's Disease Patients Who Have Previously Received vCR Stimulation

Who this might be right for
Parkinson Disease
Stanford University 5
Early research (Phase 1)Ended earlyNCT04135352
What this trial is testing

Intratumoral/Intralesional Administration of V938 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic or Recurrent Malignancies (V938-001)

Who this might be right for
Neoplasm Metastasis
Merck Sharp & Dohme LLC 35
Not applicableNot Yet RecruitingNCT07764874
What this trial is testing

Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in Advanced Parkinson's Disease.

Who this might be right for
Parkinson Disease
InSightec 120
Not applicableStudy completedNCT03872414
What this trial is testing

Emotion Study/Substudy: Flexible Brain Study

Who this might be right for
AgingEmotionsParkinson Disease
University of Florida 46
Early research (Phase 1)Study completedNCT01295827
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)

Who this might be right for
Cancer, Solid Tumor
Merck Sharp & Dohme LLC 1,260
Post-approval studies (Phase 4)Study completedNCT01744496
What this trial is testing

Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain

Who this might be right for
Advanced Idiopathic Parkinson's Disease
UCB BIOSCIENCES GmbH 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT02726386
What this trial is testing

A Long Term Safety Study of ND0612 Administered as a Continuous SC Infusion in Advanced Parkinson's Disease

Who this might be right for
Parkinson's Disease
NeuroDerm Ltd. 214
Not applicableLooking for participantsNCT07313176
What this trial is testing

Long Term Effectiveness of Levodopa-Entacapone-Carbidopa Intestinal Gel in Participants With Advanced Parkinson's Disease

Who this might be right for
Advanced Parkinson Disease
Britannia Pharmaceuticals Ltd. 215
Not applicableActive Not RecruitingNCT06107426
What this trial is testing

Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease

Who this might be right for
Parkinson's Disease (PD)
AbbVie 427
Post-approval studies (Phase 4)Study completedNCT00307450
What this trial is testing

Efficacy and Safety of Levetiracetam Versus Placebo on Levodopa-induced Dyskinesias in Advanced Parkinson's Disease

Who this might be right for
Parkinson's Disease
Technische Universität Dresden 34
Post-approval studies (Phase 4)Study completedNCT01711866
What this trial is testing

A Phase 4, Open-label Study to Assess the Feasibility and Efficacy on Motor and Non-motor Symptoms of Switching From Pramipexole or Ropinirole to Rotigotine Transdermal Patch in Subjects With Advanced Idiopathic Parkinson's Disease

Who this might be right for
Advanced Idiopathic Parkinson's Disease
UCB BIOSCIENCES GmbH 87
Not applicableLooking for participantsNCT05539196
What this trial is testing

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Who this might be right for
Movement DisordersNeurologyParkinsons Disease
InSightec 60
Large-scale testing (Phase 3)Study completedNCT01130493
What this trial is testing

Compare IPX066 and Carbidopa/Levodopa/Entacapone (CLE) Followed by an Open-Label Safety Study of IPX066

Who this might be right for
Parkinson's Disease
Impax Laboratories, LLC 110
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