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Results for “Advanced Rare Tumours”

63 trials

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Showing 20 of 63 results

Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Testing effectiveness (Phase 2)UnknownNCT05548348
What this trial is testing

First-line Furmonertinib in Advanced NSCLC Patients With EGFR Uncommon Mutation

Who this might be right for
Non-small Cell Lung CancerEGFR G719XEGFR L861Q+1 more
Chongqing University Cancer Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT05168566
What this trial is testing

Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Teligene US 99
Testing effectiveness (Phase 2)Looking for participantsNCT06010329
What this trial is testing

Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Teligene US 66
Large-scale testing (Phase 3)Looking for participantsNCT02305654
What this trial is testing

International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

Who this might be right for
Squamous Cell Carcinoma of the Penis, Usual Type
Institute of Cancer Research, United Kingdom 200
Testing effectiveness (Phase 2)Study completedNCT01755195
What this trial is testing

Cabozantinib for Adults With Advanced Soft Tissue Sarcoma

Who this might be right for
Refractory Soft Tissue Sarcomas
National Cancer Institute (NCI) 55
Not applicableLooking for participantsNCT07374692
What this trial is testing

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

Who this might be right for
Recurrent CNS TumorsBrain CancerGliomas+3 more
National Cancer Institute (NCI) 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT06638931
What this trial is testing

Agnostic Therapy in Rare Solid Tumors

Who this might be right for
Urachal CancerParathyroid CarcinomaFibrolamellar Carcinoma+38 more
Instituto do Cancer do Estado de São Paulo 28
Testing effectiveness (Phase 2)Study completedNCT03840772
What this trial is testing

Eribulin in Advanced Solitary Fibrous Tumor

Who this might be right for
Solitary Fibrous Tumor
Italian Sarcoma Group 16
Testing effectiveness (Phase 2)Temporarily pausedNCT05337735
What this trial is testing

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Who this might be right for
Microsatellite High CancersPeritoneal MesotheliomaExtrapulmonary High Grade+5 more
M.D. Anderson Cancer Center 140
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Early research (Phase 1)Study completedNCT02736565
What this trial is testing

Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma

Who this might be right for
Ewing's SarcomaEwing Family of TumorsEwing's Tumor Metastatic+4 more
Gradalis, Inc. 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT02721732
What this trial is testing

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Who this might be right for
Advanced Malignant Solid NeoplasmCarcinoma of Unknown PrimaryMetastatic Adrenal Gland Pheochromocytoma+16 more
M.D. Anderson Cancer Center 157
Testing effectiveness (Phase 2)Looking for participantsNCT07046650
What this trial is testing

Multi-cohort, Single-arm, Phase II Study of the Efficacy and Side Effects of Cisplatin Plus Gemcitabine in the Treatment of PD1 Failure or Intensive Treatment of Some Rare Tumors

Who this might be right for
Advanced Solid Tumors
Sheng Zhang 84
Not applicableLooking for participantsNCT02906943
What this trial is testing

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

Who this might be right for
Breast CancerLung CancerColorectal Cancer+8 more
University Health Network, Toronto 10,000
Testing effectiveness (Phase 2)Study completedNCT04551521
What this trial is testing

CRAFT: The NCT-PMO-1602 Phase II Trial

Who this might be right for
Metastatic or Locally Advanced Malignancies
German Cancer Research Center 72
Testing effectiveness (Phase 2)Ended earlyNCT05215951
What this trial is testing

Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC

Who this might be right for
Lung Cancer
AstraZeneca 4
Not applicableActive Not RecruitingNCT01505400
What this trial is testing

Integrated Molecular Profiling in Advanced Cancers Trial

Who this might be right for
Breast CancerNon-small Cell Lung CancerColorectal Cancer+7 more
University Health Network, Toronto 3,026
Testing effectiveness (Phase 2)Looking for participantsNCT06683846
What this trial is testing

Ivonescimab in the Treatment of Multiple Advanced Tumors

Who this might be right for
Pheochromocytoma/ParagangliomaRhabdomyosarcomaPaget Disease, Extramammary+16 more
Fudan University 400
Testing effectiveness (Phase 2)Ended earlyNCT05017103
What this trial is testing

Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study

Who this might be right for
Locally Advanced Undifferentiated Pleomorphic SarcomaMetastatic Undifferentiated Pleomorphic SarcomaRecurrent Undifferentiated Pleomorphic Sarcoma+1 more
M.D. Anderson Cancer Center 6
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