Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Refractory Solid Tumors”

598 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 598 results

Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Early research (Phase 1)UnknownNCT03645200
What this trial is testing

Treatment of Carrying TP53 Harmful Mutations

Who this might be right for
Advanced Cancer
Tianjin Medical University Second Hospital 60
Early research (Phase 1)Study completedNCT04811898
What this trial is testing

A Dose Escalation Study of LNA-i-Mir-221 for Cancer Treatment

Who this might be right for
Multiple Myeloma, RefractoryHepatocarcinomaAdvanced Solid Tumor
Azienda Ospedaliera Universitaria Mater Domini, Catanzaro 17
Early research (Phase 1)Ended earlyNCT01159301
What this trial is testing

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+16 more
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439175
What this trial is testing

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 70
Early research (Phase 1)Study completedNCT01585870
What this trial is testing

Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of Sorafenib and Eribulin in Combination

Who this might be right for
Neoplasms
Bayer 40
Early research (Phase 1)Study completedNCT01875601
What this trial is testing

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

Who this might be right for
Solid TumorsBrain TumorsSarcoma+2 more
National Cancer Institute (NCI) 16
Early research (Phase 1)Study completedNCT01106508
What this trial is testing

A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsRecurrent or Refractory MedulloblastomaLocally Advanced or Metastatic Basal Cell Carcinoma
Novartis Pharmaceuticals 57
Testing effectiveness (Phase 2)Study completedNCT01078662
What this trial is testing

Open Label Study to Assess Efficacy and Safety of Olaparib in Confirmed Genetic BRCA1 or BRCA2 Mutation Pats

Who this might be right for
OvarianBreastProstate+2 more
AstraZeneca 298
Early research (Phase 1)UnknownNCT05650580
What this trial is testing

TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors

Who this might be right for
Non-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma RefractoryAdvanced Solid Tumor
Tarapeutics Science Inc. 26
Early research (Phase 1)Study completedNCT00049023
What this trial is testing

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsGastrointestinal Carcinoid TumorIslet Cell Tumor+4 more
O'Dorisio, M S 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT04243499
What this trial is testing

First-in-Human Study of ICT01 in Patients With Advanced Cancer

Who this might be right for
Solid Tumor, AdultHematopoietic/Lymphoid Cancer
ImCheck Therapeutics, an Ipsen company 293
Early research (Phase 1)Looking for participantsNCT05607498
What this trial is testing

First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors or Relapse/Refractory Lymphoma

Who this might be right for
Advanced/Metastatic Solid TumorsRelapse/Refractory Lymphoma
EpimAb Biotherapeutics (Suzhou)Co., Ltd. 150
Testing effectiveness (Phase 2)Ended earlyNCT03323398
What this trial is testing

Dose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durvalumab for Participants With Advanced Malignancies

Who this might be right for
Relapsed/Refractory Solid Tumor Malignancies or LymphomaOvarian Cancer
ModernaTX, Inc. 79
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Study completedNCT01324479
What this trial is testing

Study of INC280 in Patients With c-MET Dependent Advanced Solid Tumors

Who this might be right for
Solid Tumors
Novartis Pharmaceuticals 131
Testing effectiveness (Phase 2)Study completedNCT04819373
What this trial is testing

BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors

Who this might be right for
Tumor, Solid
Eikon Therapeutics 1
Early research (Phase 1)Study completedNCT00567931
What this trial is testing

1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 52
Not applicableUnknownNCT05438342
What this trial is testing

An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis

Who this might be right for
Advanced CancerMetastatic Cancer
Shanghai Pudong Hospital 195
Testing effectiveness (Phase 2)Looking for participantsNCT04803318
What this trial is testing

Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultHepatocellular Carcinoma
Second Affiliated Hospital of Guangzhou Medical University 100
Next Page