Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Refractory Solid Tumors”

587 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 587 results

Early research (Phase 1)Study completedNCT00004059
What this trial is testing

Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT02451553
What this trial is testing

Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmBile Duct CarcinomaRecurrent Malignant Solid Neoplasm+4 more
University of Washington 41
Early research (Phase 1)Looking for participantsNCT06873659
What this trial is testing

SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorGastric CancerLiver Cancer
Qurgen Inc. 96
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Early research (Phase 1)Study completedNCT00567931
What this trial is testing

1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 52
Testing effectiveness (Phase 2)Looking for participantsNCT04390737
What this trial is testing

Evaluate the Safety and Clinical Activity of HH2853

Who this might be right for
FL LymphomaEpithelioid SarcomaPeripheral T Cell Lymphoma+1 more
Haihe Biopharma Co., Ltd. 254
Early research (Phase 1)Study completedNCT01544322
What this trial is testing

Dose Escalation Study of the Safety and Pharmacokinetics of ME-344 Single Agent for Refractory Solid Tumors

Who this might be right for
Solid Tumors
MEI Pharma, Inc. 24
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Testing effectiveness (Phase 2)Study completedNCT01949688
What this trial is testing

Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*24 or A*02-positive Advanced Solid Tumors

Who this might be right for
Solid Tumors
Shiga University 26
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT01430572
What this trial is testing

Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

Who this might be right for
Advanced CancersSolid Tumors
M.D. Anderson Cancer Center 62
Early research (Phase 1)Study completedNCT00207012
What this trial is testing

MAD Refractory: Solid Tumor QD w/o Break

Who this might be right for
HER2 or EGFR Expressing Advanced Solid Malignancies
Bristol-Myers Squibb 45
Early research (Phase 1)UnknownNCT05564806
What this trial is testing

Study of YH004 (4-1BB Agonist Antibody) in Advanced Solid Tumors And Relapsed Or Refractory Non-Hodgkin Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed Or Refractory Non-Hodgkin Lymphoma
Eucure (Beijing) Biopharma Co., Ltd 38
Early research (Phase 1)Study completedNCT05501821
What this trial is testing

Study of KBA1412 in Participants With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Tumor Malignancy
Kling Biotherapeutics B.V. 16
Testing effectiveness (Phase 2)UnknownNCT05115500
What this trial is testing

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Who this might be right for
CarcinomaSolid Tumor
Second Affiliated Hospital of Soochow University 55
Early research (Phase 1)Study completedNCT02743637
What this trial is testing

A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors

Who this might be right for
Advanced MalignancyAdvanced Solid TumorsNeoplasm+1 more
SynDevRx, Inc. 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439357
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 4
Early research (Phase 1)Ended earlyNCT00976508
What this trial is testing

Figitumumab Combined With Pegvisomant For Advanced Solid Tumors

Who this might be right for
Colorectal NeoplasmsLung NeoplasmsBreast Neoplasms+2 more
Pfizer 24
Early research (Phase 1)Study completedNCT01628640
What this trial is testing

Viral Therapy in Treating Patient With Refractory Liver Cancer or Advanced Solid Tumors

Who this might be right for
Advanced Malignant Solid NeoplasmHepatocellular Carcinoma
Mayo Clinic 17
Load More Results
150