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Results for “Advanced Solid Tumors and Hematologic Malignancies”

282 trials

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Showing 20 of 282 results

Early research (Phase 1)Study completedNCT00006221
What this trial is testing

BMS-247550 in Treating Patients With Advanced Cancers

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439110
What this trial is testing

Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 38
Early research (Phase 1)Study completedNCT04257617
What this trial is testing

A Trial of ZL-1201 in Subjects With Advanced Cancer

Who this might be right for
Advanced Cancer
Zai Lab (Shanghai) Co., Ltd. 37
Early research (Phase 1)Ended earlyNCT05338346
What this trial is testing

ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies

Who this might be right for
Advanced Solid TumorsHematological Malignancies
Antengene Discovery Limited 22
Early research (Phase 1)Study completedNCT00646139
What this trial is testing

KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment

Who this might be right for
LymphomaLymphoproliferative DisorderSmall Intestine Cancer+1 more
Roswell Park Cancer Institute 7
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Testing effectiveness (Phase 2)Looking for participantsNCT02693535
What this trial is testing

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Who this might be right for
Lymphoma, Non-HodgkinMultiple MyelomaAdvanced Solid Tumors
American Society of Clinical Oncology 4,200
Early research (Phase 1)Study completedNCT01949545
What this trial is testing

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Solid TumorsHematologic MalignanciesHepatic Impairment
Amgen 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439123
What this trial is testing

Testing AZD5363 as a Potential Targeted Treatment in Cancers With AKT Genetic Changes (MATCH-Subprotocol Y)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT01375842
What this trial is testing

Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tolerability and Pharmacokinetics in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
TumorsHematologic Malignancies
Genentech, Inc. 661
Testing effectiveness (Phase 2)Ended earlyNCT03648372
What this trial is testing

TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

Who this might be right for
NeoplasmsLymphomaHematologic Neoplasms
Takeda 109
Early research (Phase 1)Study completedNCT02507544
What this trial is testing

A Safety and Pharmacokinetic Study of TRX-818 Administered Orally to Patients With Advanced Cancer

Who this might be right for
CarcinomaAdvanced Cancer
TaiRx, Inc. 36
Early research (Phase 1)Study completedNCT00749502
What this trial is testing

MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8)

Who this might be right for
Solid TumorsChronic Lymphocytic LeukemiaT-cell-prolymphocytic Leukemia
Tesaro, Inc. 113
Testing effectiveness (Phase 2)Active Not RecruitingNCT06390865
What this trial is testing

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI) 49
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439136
What this trial is testing

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 40
Early research (Phase 1)UnknownNCT05415098
What this trial is testing

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Who this might be right for
Nasopharyngeal CarcinomaCastrate Resistant Prostate CancerGastric Cancer+6 more
Ascentage Pharma Group Inc. 90
Early research (Phase 1)Looking for participantsNCT06801002
What this trial is testing

Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

Who this might be right for
Solid Tumor
Jabez Bioscience, Inc 25
Large-scale testing (Phase 3)Looking for participantsNCT06401356
What this trial is testing

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Who this might be right for
Hematologic MalignancySolid TumorAdvanced Malignancies
Novartis Pharmaceuticals 50
Testing effectiveness (Phase 2)Ended earlyNCT02712905
What this trial is testing

An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 116
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