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Results for “Advanced Solid Tumors and Hematological Malignancies”

134 trials

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Showing 20 of 134 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04439110
What this trial is testing

Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 38
Early research (Phase 1)Study completedNCT04257617
What this trial is testing

A Trial of ZL-1201 in Subjects With Advanced Cancer

Who this might be right for
Advanced Cancer
Zai Lab (Shanghai) Co., Ltd. 37
Early research (Phase 1)Ended earlyNCT05338346
What this trial is testing

ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies

Who this might be right for
Advanced Solid TumorsHematological Malignancies
Antengene Discovery Limited 22
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT01949545
What this trial is testing

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Solid TumorsHematologic MalignanciesHepatic Impairment
Amgen 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439123
What this trial is testing

Testing AZD5363 as a Potential Targeted Treatment in Cancers With AKT Genetic Changes (MATCH-Subprotocol Y)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT01375842
What this trial is testing

Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tolerability and Pharmacokinetics in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
TumorsHematologic Malignancies
Genentech, Inc. 661
Testing effectiveness (Phase 2)Ended earlyNCT03648372
What this trial is testing

TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

Who this might be right for
NeoplasmsLymphomaHematologic Neoplasms
Takeda 109
Early research (Phase 1)Study completedNCT00749502
What this trial is testing

MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8)

Who this might be right for
Solid TumorsChronic Lymphocytic LeukemiaT-cell-prolymphocytic Leukemia
Tesaro, Inc. 113
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439136
What this trial is testing

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 40
Early research (Phase 1)UnknownNCT05415098
What this trial is testing

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Who this might be right for
Nasopharyngeal CarcinomaCastrate Resistant Prostate CancerGastric Cancer+6 more
Ascentage Pharma Group Inc. 90
Early research (Phase 1)Looking for participantsNCT06801002
What this trial is testing

Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

Who this might be right for
Solid Tumor
Jabez Bioscience, Inc 25
Large-scale testing (Phase 3)Looking for participantsNCT06401356
What this trial is testing

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Who this might be right for
Hematologic MalignancySolid TumorAdvanced Malignancies
Novartis Pharmaceuticals 50
Testing effectiveness (Phase 2)Ended earlyNCT02712905
What this trial is testing

An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 116
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439344
What this trial is testing

Testing Binimetinib as a Potential Targeted Treatment in Cancers With NRAS Genetic Changes (MATCH-Subprotocol Z1A)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 53
Early research (Phase 1)WithdrawnNCT00009828
What this trial is testing

Paclitaxel Combined With Fluorouracil-Uracil and Leucovorin in Treating Patients With Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
University of Pittsburgh
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439357
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 4
Early research (Phase 1)Study completedNCT05391022
What this trial is testing

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies

Who this might be right for
Advanced MalignanciesSolid TumorHematological Malignancy
Constellation Pharmaceuticals 35
Early research (Phase 1)Study completedNCT00003451
What this trial is testing

Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
National Cancer Institute (NCI) 40
Not applicableNot Yet RecruitingNCT04871477
What this trial is testing

Adoption of Audio Recording in the Outpatient Supportive Care Center

Who this might be right for
Advanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmLocally Advanced Malignant Solid Neoplasm+2 more
M.D. Anderson Cancer Center 200
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