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Results for “Advanced Solid Tumors and Hematological Malignancies”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01351350
What this trial is testing

Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies

Who this might be right for
Advanced Solid MalignanciesHematologic Malignancies
Millennium Pharmaceuticals, Inc. 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439279
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439227
What this trial is testing

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439201
What this trial is testing

Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Amplification (MATCH-Subprotocol Z1B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+2 more
National Cancer Institute (NCI) 40
Early research (Phase 1)UnknownNCT00004036
What this trial is testing

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersDrug/Agent Toxicity by Tissue/OrganLeukemia+5 more
The Cleveland Clinic 30
Early research (Phase 1)Not Yet RecruitingNCT06528249
What this trial is testing

Safety, Tolerability and Preliminary Efficacy of Erythrocyte-αPD-1 Conjugate in Patients With Advanced Malignancies

Who this might be right for
CancerSolid TumorHematologic Malignancy
Zhejiang Provincial People's Hospital 39
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT03886831
What this trial is testing

PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies

Who this might be right for
Relapsed/Refractory Advanced Solid TumorsRelapsed/Refractory Diffuse Large B-cell LymphomaRelapsed/Refractory Myelodysplasia+5 more
Prelude Therapeutics Incorporated 232
Early research (Phase 1)Temporarily pausedNCT03722186
What this trial is testing

Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies

Who this might be right for
Physiological Effects of DrugsNeoplasms by Histologic TypeLymphoma+3 more
Jiangsu HengRui Medicine Co., Ltd. 128
Early research (Phase 1)Ended earlyNCT02706392
What this trial is testing

Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid NeoplasmMetastatic Lung Non-Small Cell Carcinoma+10 more
Fred Hutchinson Cancer Center 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439175
What this trial is testing

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Looking for participantsNCT05159245
What this trial is testing

The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs

Who this might be right for
Advanced CancerSolid TumorHaematological Malignancy
Helsinki University Central Hospital 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT02465060
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmBladder Carcinoma+49 more
National Cancer Institute (NCI) 6,452
Large-scale testing (Phase 3)Study completedNCT00006348
What this trial is testing

Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+7 more
Alliance for Clinical Trials in Oncology 100
Early research (Phase 1)Study completedNCT00045006
What this trial is testing

Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04243499
What this trial is testing

First-in-Human Study of ICT01 in Patients With Advanced Cancer

Who this might be right for
Solid Tumor, AdultHematopoietic/Lymphoid Cancer
ImCheck Therapeutics, an Ipsen company 293
Early research (Phase 1)Study completedNCT01183663
What this trial is testing

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 180
Early research (Phase 1)Looking for participantsNCT05892718
What this trial is testing

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Who this might be right for
Advanced Solid TumorRefractory Non-Hodgkin Lymphoma
FBD Biologics Limited 80
Large-scale testing (Phase 3)Looking for participantsNCT03486873
What this trial is testing

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Who this might be right for
Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC 3,500
Not applicableStudy completedNCT04389541
What this trial is testing

Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology

Who this might be right for
Advanced Solid Tumors or Hematologic Malignancies
iOMEDICO AG 499
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