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Results for “Advanced Uveal Melanoma”

60 trials

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Showing 20 of 60 results

Testing effectiveness (Phase 2)WithdrawnNCT03326258
What this trial is testing

Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmEstrogen Receptor NegativeGPNMB Positive+15 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT00072345
What this trial is testing

Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Intraocular MelanomaMelanoma (Skin)
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT05677373
What this trial is testing

Testing the Safety and Effectiveness of Combining Two Drugs, PLX2853 and Trametinib in the Treatment of Advanced Uveal Melanoma

Who this might be right for
Advanced Uveal MelanomaMetastatic Uveal MelanomaUnresectable Uveal Melanoma
Alliance for Clinical Trials in Oncology
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07406724
What this trial is testing

HS-IT101 Injection Versus Chemotherapy in the Treatment of Advanced Melanoma

Who this might be right for
Melanoma (Excluding Uveal Melanoma)
Qingdao Sino-Cell Biomedicine Co., Ltd. 90
Testing effectiveness (Phase 2)Looking for participantsNCT04130516
What this trial is testing

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

Who this might be right for
Solid Tumor, Adult
Linnaeus Therapeutics, Inc. 200
Early research (Phase 1)Ended earlyNCT05047536
What this trial is testing

KZR-261 in Subjects With Advanced Solid Malignancies

Who this might be right for
Advanced/Metastatic Solid Tumor
Kezar Life Sciences, Inc. 61
Early research (Phase 1)Study completedNCT05585034
What this trial is testing

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanoma Excluding Uveal MelanomaNon-small Cell Lung Cancer, Squamous or Non-squamous+6 more
Xencor, Inc. 60
Early research (Phase 1)Looking for participantsNCT04855435
What this trial is testing

Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours

Who this might be right for
Advanced Solid TumorUveal Melanoma, MetastaticCutaneous Melanoma
MonTa Biosciences ApS 106
Testing effectiveness (Phase 2)Ended earlyNCT01533948
What this trial is testing

Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Extraocular Extension MelanomaMetastatic Intraocular MelanomaRecurrent Intraocular Melanoma+9 more
Roswell Park Cancer Institute 25
Testing effectiveness (Phase 2)Study completedNCT00109005
What this trial is testing

Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma

Who this might be right for
Melanoma
National Cancer Institute (NCI) 17
Early research (Phase 1)Study completedNCT03297424
What this trial is testing

PLX2853 in Advanced Malignancies.

Who this might be right for
Small Cell Lung CancerUveal MelanomaOvarian Clear Cell Carcinoma+5 more
Opna Bio LLC 49
Early research (Phase 1)Ended earlyNCT05576077
What this trial is testing

TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors

Who this might be right for
Breast CancerColorectal CancerUveal Melanoma+3 more
Turnstone Biologics, Corp. 31
Early research (Phase 1)Looking for participantsNCT06022029
What this trial is testing

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

Who this might be right for
Triple Negative Breast CancerDiffuse Large B Cell LymphomaFollicular Lymphoma+11 more
OncoNano Medicine, Inc. 168
Testing effectiveness (Phase 2)Looking for participantsNCT05524935
What this trial is testing

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

Who this might be right for
Uveal MelanomaOcular Melanoma
H. Lee Moffitt Cancer Center and Research Institute 37
Early research (Phase 1)Study completedNCT02315066
What this trial is testing

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

Who this might be right for
Neoplasms
Pfizer 174
Early research (Phase 1)Ended earlyNCT02029690
What this trial is testing

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin

Who this might be right for
Pleural Mesothelioma Malignant AdvancedPeritoneal Mesothelioma Malignant AdvancedNon-squamous Non-small Cell Lung Carcinoma+4 more
Polaris Group 85
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT04283890
What this trial is testing

PHP and Immunotherapy in Metastasized UM

Who this might be right for
Uveal Melanoma, Metastatic
Leiden University Medical Center 83
Testing effectiveness (Phase 2)Study completedNCT04993677
What this trial is testing

SEA-CD40 Given With Other Drugs in Cancers

Who this might be right for
MelanomaCarcinoma, Non-Small- Cell Lung
Seagen Inc. 77
Large-scale testing (Phase 3)Study completedNCT01989572
What this trial is testing

Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery

Who this might be right for
Iris MelanomaMedium/Large Size Posterior Uveal MelanomaMucosal Melanoma+17 more
National Cancer Institute (NCI) 815
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