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Results for “Advanced or Metastatic CRC”

399 trials

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Showing 20 of 399 results

Early research (Phase 1)Ended earlyNCT04294160
What this trial is testing

Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

Who this might be right for
BRAF V600 Colorectal Cancer
Novartis Pharmaceuticals 122
Early research (Phase 1)Study completedNCT03289962
What this trial is testing

Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
MelanomaNon-Small Cell Lung CancerBladder Cancer+5 more
Genentech, Inc. 272
Large-scale testing (Phase 3)Looking for participantsNCT06997497
What this trial is testing

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Who this might be right for
Colon AdenocarcinomaRectal Adenocarcinoma
Merck Sharp & Dohme LLC 477
Early research (Phase 1)Study completedNCT04306900
What this trial is testing

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

Who this might be right for
Solid Tumor, Adult
Trishula Therapeutics, Inc. 185
Large-scale testing (Phase 3)Ended earlyNCT00070122
What this trial is testing

Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer

Who this might be right for
Adenocarcinoma of the ColonAdenocarcinoma of the RectumRecurrent Colon Cancer+5 more
National Cancer Institute (NCI) 2,200
Early research (Phase 1)Study completedNCT03287427
What this trial is testing

MYPHISMO: MYB and PD-1 Immunotherapies Against Multiple Oncologies Trial

Who this might be right for
Colorectal CancerAdenoid Cystic Carcinoma
Peter MacCallum Cancer Centre, Australia 27
Large-scale testing (Phase 3)Study completedNCT00911170
What this trial is testing

PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study

Who this might be right for
CancerColon CancerColorectal Cancer+5 more
Amgen 847
Testing effectiveness (Phase 2)Study completedNCT00066846
What this trial is testing

Bevacizumab Plus Fluorouracil and Leucovorin in Treating Patients With Locally Advanced or Metastatic Stage IV Colorectal Cancer That Has Progressed After Standard Chemotherapy

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI)
Early research (Phase 1)Active Not RecruitingNCT03845166
What this trial is testing

XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors

Who this might be right for
Neoplasm MalignantRenal Cell CarcinomaHormone Receptor Positive Breast Carcinoma+2 more
Exelixis 325
Testing effectiveness (Phase 2)Ended earlyNCT05716295
What this trial is testing

A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Medikine, Inc. 26
Large-scale testing (Phase 3)Temporarily pausedNCT00316745
What this trial is testing

IRIS Followed by mFOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Hokkaido Gastrointestinal Cancer Study Group 200
Not applicableStudy completedNCT05424068
What this trial is testing

Rehabilitation for People With Advanced Cancer

Who this might be right for
Advanced Breast CancerAdvanced Colorectal CancerCancer Rehabilitation
University Health Network, Toronto 111
Testing effectiveness (Phase 2)Looking for participantsNCT03526835
What this trial is testing

Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced/Metastatic Solid TumorsColorectal CancerGastric Cancer+5 more
Merus B.V. 523
Testing effectiveness (Phase 2)Looking for participantsNCT06553885
What this trial is testing

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

Who this might be right for
Metastatic Colorectal CancerHepatocellular Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 40
Testing effectiveness (Phase 2)Looking for participantsNCT04657068
What this trial is testing

ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced CancerMetastatic CancerOvarian Cancer+6 more
Artios Pharma Ltd 442
Testing effectiveness (Phase 2)WithdrawnNCT06690281
What this trial is testing

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Who this might be right for
Gastrointestinal CarcinomaPancreatic CancerHepatocellular Cancer+5 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03317119
What this trial is testing

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colon CarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Carcinoma+22 more
City of Hope Medical Center 26
Early research (Phase 1)Study completedNCT02310464
What this trial is testing

Trial of Active Immunotherapy With OBI-833 (Globo H-CRM197) in Advanced/Metastatic Gastric, Lung, Colorectal or Breast Cancer Subjects

Who this might be right for
Metastatic Gastric CancerMetastatic Breast CancerMetastatic Colorectal Cancer+1 more
OBI Pharma, Inc 25
Testing effectiveness (Phase 2)Looking for participantsNCT07042685
What this trial is testing

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)
The Methodist Hospital Research Institute 50
Early research (Phase 1)Study completedNCT02636036
What this trial is testing

Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors

Who this might be right for
Colorectal CancerSquamous Cell Carcinoma of the Head and NeckEpithelial Tumor
Akamis Bio 51
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