Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced or Metastatic Head and Neck Squamous Cell Carcinoma”

255 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 255 results

Testing effectiveness (Phase 2)Ended earlyNCT01313390
What this trial is testing

Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or Metastatic Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
University College, London 4
Early research (Phase 1)Study completedNCT03811652
What this trial is testing

A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non Small Cell Lung Cancer Squamous (NSCLC-Sq)Head and Neck Squamous Cell Carcinoma (HNSCC)Small Cell Lung Cancer (SCLC)+3 more
MedImmune LLC 8
Early research (Phase 1)Looking for participantsNCT07232524
What this trial is testing

BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 16
Early research (Phase 1)Active Not RecruitingNCT02495896
What this trial is testing

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic AdenocarcinomaNon-Resectable Cholangiocarcinoma+13 more
University of Southern California 61
Early research (Phase 1)Active Not RecruitingNCT05653882
What this trial is testing

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Who this might be right for
Solid TumorNon Small Cell Lung CancerMelanoma+2 more
Asher Biotherapeutics, Inc. 552
Large-scale testing (Phase 3)Study completedNCT04540211
What this trial is testing

Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma

Who this might be right for
Esophageal Cancer
Hoffmann-La Roche 461
Testing effectiveness (Phase 2)Study completedNCT00002984
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center 26
Large-scale testing (Phase 3)Study completedNCT02564263
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)

Who this might be right for
Esophageal CarcinomaEsophagogastric Junction Carcinoma
Merck Sharp & Dohme LLC 628
Early research (Phase 1)Looking for participantsNCT06545331
What this trial is testing

Study of XB010 in Subjects With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsEsophageal Squamous Cell CancerHead and Neck Squamous Cell Cancer+3 more
Exelixis 396
Testing effectiveness (Phase 2)UnknownNCT01527877
What this trial is testing

Study of BKM120 in Advanced Squamous Cell Carcinoma of Head and Neck

Who this might be right for
Head Neck Cancer Squamous Cell MetastaticHead Neck Cancer Squamous Cell Recurrent
Yonsei University 53
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Early research (Phase 1)Active Not RecruitingNCT04670679
What this trial is testing

A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 200
Early research (Phase 1)Looking for participantsNCT05783622
What this trial is testing

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Non-Small Cell Lung CancerRenal Cell CarcinomaSquamous Cell Carcinoma of the Head and Neck+4 more
Janux Therapeutics 130
Early research (Phase 1)Active Not RecruitingNCT03983954
What this trial is testing

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

Who this might be right for
ER+ Breast CancerOvarian CancerCervical Squamous Cell Carcinoma+17 more
NeoTX Therapeutics Ltd. 120
Testing effectiveness (Phase 2)Looking for participantsNCT07172802
What this trial is testing

GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Cancer (NSCLC)+3 more
GI Innovation, Inc. 76
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Early research (Phase 1)Study completedNCT02573259
What this trial is testing

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

Who this might be right for
Part 1MELANOMASCCHN+6 more
Pfizer 147
Early research (Phase 1)Study completedNCT01872923
What this trial is testing

Dose Escalating Study for Amphinex-based PCI of Bleomycin.

Who this might be right for
Cutaneous or Sub-cutaneous Malignancies
PCI Biotech AS 3
Early research (Phase 1)Ended earlyNCT04152018
What this trial is testing

Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckRenal Cell CarcinomaOvarian Cancer+8 more
Pfizer 85
Load More Results