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Results for “Advanced or Metastatic Solid Malignancy”

1,437 trials

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Showing 20 of 1,437 results

Early research (Phase 1)Study completedNCT01629758
What this trial is testing

Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors

Who this might be right for
Neoplasms by Site
Bristol-Myers Squibb 33
Early research (Phase 1)Looking for participantsNCT07182149
What this trial is testing

NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Who this might be right for
HNSCCESCCEsophageal Adenocarcinoma+7 more
Normunity AccelCo, Inc. 150
Early research (Phase 1)Active Not RecruitingNCT03502733
What this trial is testing

Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI) 64
Early research (Phase 1)Study completedNCT04857138
What this trial is testing

Evaluate Safety, Pharmacokinetics and Anti-Tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 80
Early research (Phase 1)Study completedNCT00030368
What this trial is testing

Bortezomib and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 45
Early research (Phase 1)Study completedNCT05065710
What this trial is testing

ZL-1211 in Patients With Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Zai Biopharmaceutical (Suzhou) Co., Ltd. 34
Testing effectiveness (Phase 2)Looking for participantsNCT05636215
What this trial is testing

A First-in-human Study of IBI354 in Subjects with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 368
Early research (Phase 1)Study completedNCT00499135
What this trial is testing

Sunitinib Malate in Treating Patients With Unresectable or Metastatic Kidney Cancer or Other Advanced Solid Tumors

Who this might be right for
Adult Solid NeoplasmClear Cell Renal Cell CarcinomaRecurrent Renal Cell Carcinoma+2 more
National Cancer Institute (NCI) 25
Testing effectiveness (Phase 2)Looking for participantsNCT05970497
What this trial is testing

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerMelanoma Stage IIIMelanoma Stage IV+1 more
Krystal Biotech, Inc. 240
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07780318
What this trial is testing

BL-M08D in Patients With Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors

Who this might be right for
Gastrointestinal TumorsSolid Tumors
Sichuan Baili Pharmaceutical Co., Ltd. 60
Early research (Phase 1)Active Not RecruitingNCT05717348
What this trial is testing

ES014 in Patients With Locally Advanced or Metastatic Solid Tumours

Who this might be right for
Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor
Elpiscience (Suzhou) Biopharma, Ltd. 120
Very early researchEnded earlyNCT03454243
What this trial is testing

Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Hoffmann-La Roche 1
Testing effectiveness (Phase 2)Looking for participantsNCT07486089
What this trial is testing

Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)HER2-positive Breast CancerTriple-Negative Breast Cancer (TNBC)
Beijing Biotech 60
Early research (Phase 1)Study completedNCT02221960
What this trial is testing

Evaluate MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors

Who this might be right for
Recurrent or Metastatic Solid Tumors
MedImmune LLC 39
Early research (Phase 1)Study completedNCT00607724
What this trial is testing

GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Genentech, Inc. 68
Early research (Phase 1)Study completedNCT03017833
What this trial is testing

Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center 31
Not applicableStudy completedNCT01987726
What this trial is testing

Comprehensive Gene Sequencing in Guiding Treatment Recommendations Patients With Metastatic or Recurrent Solid Tumors

Who this might be right for
Recurrent Breast CancerRecurrent Colon CancerRecurrent Rectal Cancer+5 more
Ohio State University Comprehensive Cancer Center 150
Early research (Phase 1)Study completedNCT03150810
What this trial is testing

Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
BeiGene 139
Early research (Phase 1)Study completedNCT00532090
What this trial is testing

A Multiple Ascending Dose Study of R4733 in Patients With Advanced Solid Tumors.

Who this might be right for
Neoplasms
Hoffmann-La Roche 110
Early research (Phase 1)Not Yet RecruitingNCT07797907
What this trial is testing

This Clinical Study is to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Antitumor Activity of BD200 in Participants With Advanced or Metastatic Cancer.

Who this might be right for
Solid Tumor (Phase I)
Biolojic Design Ltd. 110
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