Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced or Metastatic Solid Tumor Malignancies”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT03119428
What this trial is testing

OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced CancerMetastatic Cancer
OncoMed Pharmaceuticals, Inc. 33
Large-scale testing (Phase 3)Looking for participantsNCT07044336
What this trial is testing

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Who this might be right for
Endometrial CancerMalignant Solid Tumour
AstraZeneca 800
Early research (Phase 1)Ended earlyNCT04842630
What this trial is testing

Dose Escalation and Expansion Study Of SHR-1916 In Subjects With Locally Advanced Or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Jiangsu HengRui Medicine Co., Ltd. 11
Early research (Phase 1)Study completedNCT06117371
What this trial is testing

Study of BEBT-607 Tablets in The Treatment of Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced or Metastatic Solid TumorKRAS G12C Mutation
BeBetter Med Inc 11
Early research (Phase 1)Ended earlyNCT06488716
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumour
Genentech, Inc. 12
Early research (Phase 1)Ended earlyNCT03948763
What this trial is testing

MRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)

Who this might be right for
NeoplasmsCarcinoma, Non-Small-Cell LungPancreatic Neoplasms+1 more
Merck Sharp & Dohme LLC 70
Testing effectiveness (Phase 2)Ended earlyNCT04424641
What this trial is testing

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumor(s)Prostate CancerEsophageal Cancer+5 more
Genmab 48
Early research (Phase 1)Study completedNCT02350673
What this trial is testing

Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 70
Early research (Phase 1)Looking for participantsNCT07027488
What this trial is testing

AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Melanoma and Normal or ImpairedAdvanced Melanoma
Yale University 50
Testing effectiveness (Phase 2)Study completedNCT04504942
What this trial is testing

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor, Adult
CytoDyn, Inc. 16
Early research (Phase 1)Study completedNCT00275080
What this trial is testing

Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+48 more
National Cancer Institute (NCI) 80
Early research (Phase 1)Looking for participantsNCT07535112
What this trial is testing

Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

Who this might be right for
Advanced/Metastatic Colorectal Adenocarcinoma
Bayer 130
Early research (Phase 1)Looking for participantsNCT06332430
What this trial is testing

Intratumoral CAN2109 in Subjects With Solid Tumors

Who this might be right for
Solid TumorLymphoma
Canwell Biotech Limited 27
Early research (Phase 1)Study completedNCT00058253
What this trial is testing

Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors

Who this might be right for
Recurrent Prostate CancerStage IV Prostate CancerUnspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 80
Early research (Phase 1)Study completedNCT01482377
What this trial is testing

RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin

Who this might be right for
Neoplasms
Hoffmann-La Roche 145
Testing effectiveness (Phase 2)Active Not RecruitingNCT06939283
What this trial is testing

A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma

Who this might be right for
Advanced or Metastatic Solid TumorsNon-Hodgkin Lymphoma
Werewolf Therapeutics, Inc. 100
Early research (Phase 1)Looking for participantsNCT07252479
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid Tumors (Phase 1)RAS Mutation
Adlai Nortye Biopharma Co., Ltd. 118
Early research (Phase 1)Study completedNCT03941262
What this trial is testing

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Who this might be right for
Refractory CancerMetastatic CancerRecurrent Cancer+4 more
NKGen Biotech, Inc. 27
Early research (Phase 1)Study completedNCT01295827
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)

Who this might be right for
Cancer, Solid Tumor
Merck Sharp & Dohme LLC 1,260
Early research (Phase 1)Study completedNCT01327313
What this trial is testing

EMD525797 in Solid Tumor Patients in Japan

Who this might be right for
Solid Tumor
Merck KGaA, Darmstadt, Germany 27
Next Page