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Results for “Advanced or Refractory Solid Malignancies”

301 trials

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Showing 20 of 301 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04902872
What this trial is testing

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Who this might be right for
Solid Tumor, AdultEpithelial Ovarian CancerSmall Cell Lung Carcinoma+9 more
Cybrexa Therapeutics 130
Early research (Phase 1)Study completedNCT05501821
What this trial is testing

Study of KBA1412 in Participants With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Tumor Malignancy
Kling Biotherapeutics B.V. 16
Early research (Phase 1)Looking for participantsNCT05791448
What this trial is testing

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Who this might be right for
Advanced CholangiocarcinomaAdvanced Hepatocellular CarcinomaAdvanced Malignant Solid Neoplasm+4 more
University of Southern California 36
Early research (Phase 1)Study completedNCT03406949
What this trial is testing

MGD009/MGA012 Combination in Relapsed/Refractory Cancer

Who this might be right for
Advanced Solid Tumors
MacroGenics 25
Early research (Phase 1)Study completedNCT00968981
What this trial is testing

Hedgehog Pathway Inhibitor GDC-0449 in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Who this might be right for
Solid Cancers
Genentech, Inc. 67
Early research (Phase 1)Looking for participantsNCT05892718
What this trial is testing

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Who this might be right for
Advanced Solid TumorRefractory Non-Hodgkin Lymphoma
FBD Biologics Limited 80
Not applicableNo Longer AvailableNCT05511350
What this trial is testing

Expanded Access Protocol for Subjects With Relapsed or Refractory Advanced Solid Tumors Receiving TJ210001

Who this might be right for
Solid Tumor Metastatic Cancer Advanced Cancer
I-Mab Biopharma US Limited
Early research (Phase 1)Looking for participantsNCT04485013
What this trial is testing

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Who this might be right for
Cancer
Tizona Therapeutics, Inc 240
Early research (Phase 1)Study completedNCT00816400
What this trial is testing

A Dose Escalation, Dose Expansion Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-575, in Subjects With Advanced Tumors.

Who this might be right for
Cancer
MedImmune LLC 49
Early research (Phase 1)Study completedNCT05040932
What this trial is testing

Study of YH004 (4-1BB Agonist Antibody) in Advanced or Metastatic Malignancy

Who this might be right for
Cancer
Eucure (Beijing) Biopharma Co., Ltd 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Active Not RecruitingNCT05052255
What this trial is testing

RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Ryvu Therapeutics SA 120
Early research (Phase 1)Looking for participantsNCT05631886
What this trial is testing

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

Who this might be right for
Solid Tumor, AdultLymphomaEphA2 Overexpression+4 more
Chinese PLA General Hospital 10
Early research (Phase 1)Study completedNCT04659629
What this trial is testing

NL-201 Monotherapy and in Combination With Pembrolizumab in Patients With Relapsed or Refractory Cancer

Who this might be right for
Solid TumorAdvanced Solid Tumor
Neurogene Inc. 59
Early research (Phase 1)Study completedNCT03884556
What this trial is testing

TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers

Who this might be right for
Solid TumorLymphoma
Trishula Therapeutics, Inc. 56
Early research (Phase 1)Ended earlyNCT01227941
What this trial is testing

MK-4827 in Combination With Pegylated Liposomal Doxorubicin in Participants With Advanced Solid Tumors and Ovarian Cancer (MK-4827-011)

Who this might be right for
Ovarian Cancer
Tesaro, Inc. 6
Early research (Phase 1)Study completedNCT02743637
What this trial is testing

A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors

Who this might be right for
Advanced MalignancyAdvanced Solid TumorsNeoplasm+1 more
SynDevRx, Inc. 32
Early research (Phase 1)Ended earlyNCT03690154
What this trial is testing

Evaluate FN-1501 Monotherapy in Patients With Advanced Solid Tumors and R/R AML

Who this might be right for
Advanced CancerSolid TumorsAcute Myeloid Leukemia Refractory+1 more
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 67
Early research (Phase 1)Study completedNCT01815294
What this trial is testing

A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer

Who this might be right for
NeoplasmsNeoplasms, OvarianNeoplasms, Breast+1 more
Janssen Research & Development, LLC 54
Testing effectiveness (Phase 2)Study completedNCT02694822
What this trial is testing

AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Participants With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy

Who this might be right for
Advanced Solid CancersAdvanced Solid Cancers Refractory to PD-1 and PD-L1 Therapies
Agenus Inc. 89
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