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Results for “Advanced or Refractory Solid Malignancies”

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Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT04348916
What this trial is testing

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Who this might be right for
CancerMelanomaSolid Tumor+7 more
Oncorus, Inc. 66
Early research (Phase 1)Study completedNCT00668382
What this trial is testing

Evaluate The Toxicity And Feasibility Of Intra-Tumoral Injection

Who this might be right for
Neoplasm Metastases
University of Massachusetts, Worcester 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT06400225
What this trial is testing

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI) 35
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Early research (Phase 1)Study completedNCT01471210
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Immunoregulatory Study of Urelumab (BMS-663513) in Subjects With Advanced and/or Metastatic Solid Tumors and Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Who this might be right for
Cancer - Solid Tumors and B-Cell Non-Hodgkin's Lymphoma
Bristol-Myers Squibb 124
Testing effectiveness (Phase 2)Study completedNCT03213691
What this trial is testing

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+8 more
National Cancer Institute (NCI) 21
Early research (Phase 1)Study completedNCT01962532
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma

Who this might be right for
NeoplasmsLymphomaAdenocarcinoma+1 more
Janssen Research & Development, LLC 19
Early research (Phase 1)Study completedNCT00049712
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Refractory Advanced Solid Tumors or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
University of Wisconsin, Madison
Early research (Phase 1)Study completedNCT01165385
What this trial is testing

Study With Pazopanib in Combination With Cisplatin (CDDP) in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorsMetastatic Cancer
UNICANCER 35
Early research (Phase 1)Study completedNCT01106508
What this trial is testing

A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsRecurrent or Refractory MedulloblastomaLocally Advanced or Metastatic Basal Cell Carcinoma
Novartis Pharmaceuticals 57
Early research (Phase 1)Looking for participantsNCT04678648
What this trial is testing

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmRAS MutationLung Cancer+3 more
RasCal Therapeutics, Inc. 134
Early research (Phase 1)Study completedNCT01815294
What this trial is testing

A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer

Who this might be right for
NeoplasmsNeoplasms, OvarianNeoplasms, Breast+1 more
Janssen Research & Development, LLC 54
Testing effectiveness (Phase 2)Study completedNCT02694822
What this trial is testing

AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Participants With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy

Who this might be right for
Advanced Solid CancersAdvanced Solid Cancers Refractory to PD-1 and PD-L1 Therapies
Agenus Inc. 89
Testing effectiveness (Phase 2)Looking for participantsNCT04977453
What this trial is testing

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorCervical Cancer+3 more
GI Innovation, Inc. 317
Testing effectiveness (Phase 2)Looking for participantsNCT05733000
What this trial is testing

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Colorectal CarcinomaAdvanced Gastroesophageal Junction Adenocarcinoma+30 more
Northwestern University 94
Testing effectiveness (Phase 2)Study completedNCT03602079
What this trial is testing

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Who this might be right for
HER2-positive Breast CancerHER2 Gene MutationHER-2 Gene Amplification+41 more
Klus Pharma Inc. 49
Early research (Phase 1)Active Not RecruitingNCT04485013
What this trial is testing

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Who this might be right for
Cancer
Tizona Therapeutics, Inc 240
Early research (Phase 1)Study completedNCT00543387
What this trial is testing

Treatment of Participants With Advanced and/or Refractory Solid Tumors (MK-5108-001)

Who this might be right for
Cancer, Neoplasms, Tumors
Merck Sharp & Dohme LLC 35
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
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