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Results for “African Trypanosomiasis”

32 trials

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Showing 20 of 32 results

Early research (Phase 1)Ended earlyNCT01483170
What this trial is testing

Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With Food

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 30
Large-scale testing (Phase 3)Study completedNCT03025789
What this trial is testing

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Who this might be right for
Trypanosomiasis, AfricanSleeping SicknessTrypanosomiasis; Gambian
Drugs for Neglected Diseases 174
Early research (Phase 1)Study completedNCT02571062
What this trial is testing

Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market Formulation

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 30
Not applicableWithdrawnNCT05645822
What this trial is testing

Screen and Treat Implementation for HAT Control

Who this might be right for
Sleeping SicknessTrypanosomiasis, African
Institute of Tropical Medicine, Belgium
Not applicableStudy completedNCT06060600
What this trial is testing

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

Who this might be right for
Trypanosoma Brucei Rhodesiense; Infection
Paxmedica 345
Not applicableStudy completedNCT05637632
What this trial is testing

Assessment of Recombinant HAT-RDT Specificity

Who this might be right for
Human African Trypanosomiasis
Institute of Tropical Medicine, Belgium 1,504
Large-scale testing (Phase 3)Study completedNCT05433350
What this trial is testing

Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients

Who this might be right for
Trypanosomiasis, AfricanTrypanosoma Brucei Gambiense; InfectionSleeping Sickness
Drugs for Neglected Diseases 35
Large-scale testing (Phase 3)Study completedNCT05256017
What this trial is testing

Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects

Who this might be right for
Trypanosomiasis, AfricanTrypanosoma Brucei Gambiense; InfectionSleeping Sickness
Drugs for Neglected Diseases 1,208
Not applicableStudy completedNCT01766830
What this trial is testing

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)

Who this might be right for
Visceral LeishmaniasisHuman African TrypanosomiasisEnteric Fever+9 more
University Hospital, Geneva 1,927
Testing effectiveness (Phase 2)Study completedNCT00802594
What this trial is testing

A Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Immtech Pharmaceuticals, Inc 30
Large-scale testing (Phase 3)Study completedNCT00146627
What this trial is testing

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 280
Not applicableStudy completedNCT03356665
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection

Who this might be right for
African TrypanosomiasesWest African; TrypanosomiasisSleeping Sickness; West African+1 more
Institut de Recherche pour le Developpement 10,700
Early research (Phase 1)Study completedNCT01340157
What this trial is testing

Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

Who this might be right for
PK in Healthy Volunteers
Drugs for Neglected Diseases 12
Not applicableStudy completedNCT03112655
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure

Who this might be right for
African TrypanosomiasisAfrican; Trypanosomiasis, WestSleeping Sickness; West African+1 more
Institut de Recherche pour le Developpement 88
Large-scale testing (Phase 3)Study completedNCT03087955
What this trial is testing

Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense

Who this might be right for
Trypanosomiasis, AfricanGambiense TrypanosomiasisSleeping Sickness
Drugs for Neglected Diseases 208
Early research (Phase 1)Study completedNCT04270981
What this trial is testing

ADME Study of Acoziborole in Healthy Subjects

Who this might be right for
Trypanosomiases, African
Drugs for Neglected Diseases 6
Early research (Phase 1)Study completedNCT00982904
What this trial is testing

Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the Fexinidazole

Who this might be right for
Human African Trypanosomiasis
Drugs for Neglected Diseases 108
Not applicableStudy completedNCT05466630
What this trial is testing

Prospective Evaluation of the Specificity of Serological Tests for Human African Trypanosomiasis

Who this might be right for
Human African TrypanosomiasisSleeping SicknessTrypanosoma Brucei Gambiense; Infection+1 more
Institut de Recherche pour le Developpement 1,095
Large-scale testing (Phase 3)Not Yet RecruitingNCT06356974
What this trial is testing

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)

Who this might be right for
Human African Trypanosomiasis
Drugs for Neglected Diseases 2,500
Early research (Phase 1)Study completedNCT05947604
What this trial is testing

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 20
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