Early research (Phase 1)Study completedNCT04270981What this trial is testingADME Study of Acoziborole in Healthy SubjectsWho this might be right forTrypanosomiases, African Drugs for Neglected Diseases 6
Not applicableWithdrawnNCT03394976What this trial is testingProspective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum MalariaWho this might be right forHuman African Trypanosomiasis Foundation for Innovative New Diagnostics, Switzerland
Large-scale testing (Phase 3)Study completedNCT05256017What this trial is testingSafety and Tolerability Study of Acoziborole in g-HAT Seropositive SubjectsWho this might be right forTrypanosomiasis, AfricanTrypanosoma Brucei Gambiense; InfectionSleeping Sickness Drugs for Neglected Diseases 1,208
Not applicableStudy completedNCT05637632What this trial is testingAssessment of Recombinant HAT-RDT SpecificityWho this might be right forHuman African Trypanosomiasis Institute of Tropical Medicine, Belgium 1,504
Early research (Phase 1)Study completedNCT01340157What this trial is testingFexinidazole (1200mg) Bioavailability Under Different Food Intake ConditionsWho this might be right forPK in Healthy Volunteers Drugs for Neglected Diseases 12
Not applicableStudy completedNCT03112655What this trial is testingDiagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cureWho this might be right forAfrican TrypanosomiasisAfrican; Trypanosomiasis, WestSleeping Sickness; West African+1 more Institut de Recherche pour le Developpement 88
Large-scale testing (Phase 3)Not Yet RecruitingNCT06356974What this trial is testingStop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)Who this might be right forHuman African Trypanosomiasis Drugs for Neglected Diseases 2,500
Early research (Phase 1)Study completedNCT01533961What this trial is testingHuman African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158Who this might be right forTrypanosomiasisTrypanosomiasis, AfricanProtozoan Infections+1 more Drugs for Neglected Diseases 136
Large-scale testing (Phase 3)Study completedNCT02169557What this trial is testingEfficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal StudyWho this might be right forHuman African Trypanosomiasis (HAT) Drugs for Neglected Diseases 230
Early research (Phase 1)Ended earlyNCT01483170What this trial is testingMultiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With FoodWho this might be right forTrypanosomiasis, African Drugs for Neglected Diseases 30
Early research (Phase 1)Study completedNCT00982904What this trial is testingHuman African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the FexinidazoleWho this might be right forHuman African Trypanosomiasis Drugs for Neglected Diseases 108
Not applicableStudy completedNCT05466630What this trial is testingProspective Evaluation of the Specificity of Serological Tests for Human African TrypanosomiasisWho this might be right forHuman African TrypanosomiasisSleeping SicknessTrypanosoma Brucei Gambiense; Infection+1 more Institut de Recherche pour le Developpement 1,095
Not applicableStudy completedNCT03356665What this trial is testingDiagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case DetectionWho this might be right forAfrican TrypanosomiasesWest African; TrypanosomiasisSleeping Sickness; West African+1 more Institut de Recherche pour le Developpement 10,700
Large-scale testing (Phase 3)Ended earlyNCT00489658What this trial is testingEflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, UgandaWho this might be right forTrypanosomiasis, African Epicentre 31
Not applicableStudy completedNCT06060600What this trial is testingA Retrospective Analysis of Suramin Treatment for Stage 1 TBRWho this might be right forTrypanosoma Brucei Rhodesiense; Infection Paxmedica 345
Large-scale testing (Phase 3)Study completedNCT03025789What this trial is testingFexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any StageWho this might be right forTrypanosomiasis, AfricanSleeping SicknessTrypanosomiasis; Gambian Drugs for Neglected Diseases 174
Large-scale testing (Phase 3)Study completedNCT03087955What this trial is testingEfficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. GambienseWho this might be right forTrypanosomiasis, AfricanGambiense TrypanosomiasisSleeping Sickness Drugs for Neglected Diseases 208
Testing effectiveness (Phase 2)Study completedNCT00802594What this trial is testingA Trial of DB289 for the Treatment of Stage I African TrypanosomiasisWho this might be right forTrypanosomiasis, African Immtech Pharmaceuticals, Inc 30
Large-scale testing (Phase 3)Ended earlyNCT00330148What this trial is testingRandomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African TrypanosomiasisWho this might be right forTrypanosomiasis, African Epicentre 435
Large-scale testing (Phase 3)Study completedNCT02184689What this trial is testingEfficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal StudyWho this might be right forHuman African Trypanosomiasis (HAT) Drugs for Neglected Diseases 125