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Results for “Alkylating Agents”

74 trials

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Showing 20 of 74 results

Testing effectiveness (Phase 2)Ended earlyNCT00365274
What this trial is testing

SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma

Who this might be right for
Anaplastic Large Cell Lymphoma
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Ended earlyNCT00655395
What this trial is testing

Treatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome With Laromustine and Infusional Cytarabine

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
Viron Therapeutics Inc 25
Testing effectiveness (Phase 2)Study completedNCT00281983
What this trial is testing

Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia

Who this might be right for
Chronic Lymphocytic Leukemia
German CLL Study Group 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT01659606
What this trial is testing

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Who this might be right for
Dyskeratosis CongenitaHoyeraal Hreidarsson SyndromeRevesz Syndrome+1 more
Boston Children's Hospital 40
Testing effectiveness (Phase 2)Study completedNCT03150862
What this trial is testing

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Who this might be right for
Brain and Central Nervous System Tumors
BeiGene USA, Inc. 116
Testing effectiveness (Phase 2)Study completedNCT00001498
What this trial is testing

A Pilot Trial of Sequential Chemotherapy With Antimetabolite Induction, High-Dose Alkylating Agent Consolidation With Peripheral Blood Progenitor Cell Support, and Intensification With Paclitaxel and Doxorubicin for Patients With High-Risk Breast Cancer

Who this might be right for
Breast CancerBreast Neoplasms
National Cancer Institute (NCI) 55
Testing effectiveness (Phase 2)Study completedNCT04942730
What this trial is testing

Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)

Who this might be right for
Leukemia, Acute LymphoblasticMyeloid Leukemia, AcuteBiphenotypic Acute Leukemia+3 more
St. Petersburg State Pavlov Medical University 50
Early research (Phase 1)Study completedNCT00000899
What this trial is testing

A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 10
Not applicableLooking for participantsNCT07121998
What this trial is testing

Study of Acquired Resistance to Alkylator Chemotherapy in Endocrine Neoplasms

Who this might be right for
Neuroendocrine (NE) TumorsEndocrine Cancer
Uppsala University 94
Early research (Phase 1)Study completedNCT01139970
What this trial is testing

Veliparib and Temozolomide in Treating Patients With Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome+13 more
National Cancer Institute (NCI) 66
Early research (Phase 1)Ended earlyNCT04310592
What this trial is testing

Natural Killer Cell (CYNK-001) Infusions in Adults with AML

Who this might be right for
LeukemiaLeukemia, MyeloidLeukemia, Myeloid, Acute+17 more
Celularity Incorporated 27
Testing effectiveness (Phase 2)Study completedNCT00001493
What this trial is testing

Antimetabolite Induction, High-Dose Alkylating Agent Consolidation and Retroviral Transduction of the MDR1 Gene Into Peripheral Blood Progenitor Cells Followed by Intensification Therapy With Sequential Paclitaxel and Doxorubicin for Stage 4 Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasm Metastasis
National Cancer Institute (NCI) 42
Not applicableStudy completedNCT03197532
What this trial is testing

Assessing Urinary Hormones in Female Cancer Survivors

Who this might be right for
Effects of Chemotherapy
University of Pennsylvania 38
Testing effectiveness (Phase 2)Study completedNCT02806375
What this trial is testing

PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis

Who this might be right for
Primary MyelofibrosisMyeloproliferative Disorders
St. Petersburg State Pavlov Medical University 20
Early research (Phase 1)Study completedNCT03150810
What this trial is testing

Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
BeiGene 139
Large-scale testing (Phase 3)Looking for participantsNCT05991908
What this trial is testing

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Shanghai Jiao Tong University School of Medicine 222
Testing effectiveness (Phase 2)Study completedNCT00313586
What this trial is testing

Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11+12 more
National Cancer Institute (NCI) 197
Large-scale testing (Phase 3)Study completedNCT01307579
What this trial is testing

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAdult Acute Monoblastic LeukemiaAdult Acute Monocytic Leukemia+25 more
Children's Oncology Group 517
Testing effectiveness (Phase 2)Study completedNCT00050440
What this trial is testing

Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma

Who this might be right for
Endometrial NeoplasmsUterine NeoplasmsGenital Neoplasms, Female Urogenital Neoplasms
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 50
Early research (Phase 1)Study completedNCT04177823
What this trial is testing

Belantamab Mafodotin to Investigate Safety, Tolerability, Pharmacokinetics, Immunogenicity and Clinical Activity in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Who this might be right for
Multiple Myeloma
GlaxoSmithKline 6
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