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Results for “Alpha 1-Antitrypsin Deficiency”

144 trials

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Showing 20 of 144 results

Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Not applicableEnrolling By InvitationNCT06892236
What this trial is testing

Preparation of IPSC for Cell Gene Editing for the Treatment of AATD

Who this might be right for
Alpha1-antitrypsin Deficiency
Fondazione IRCCS Policlinico San Matteo di Pavia 3
Large-scale testing (Phase 3)Study completedNCT02525861
What this trial is testing

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Who this might be right for
Alpha1-antitrypsin Deficiency
Baxalta now part of Shire 34
Not applicableEnded earlyNCT02502201
What this trial is testing

Environment Effect on Six-Minute Walk Test Performance

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha-1 Antitrypsin Deficiency
University of Florida 27
Testing effectiveness (Phase 2)Study completedNCT00067756
What this trial is testing

4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Florida 12
Testing effectiveness (Phase 2)Study completedNCT02001688
What this trial is testing

Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation"

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Kamada, Ltd. 36
Early research (Phase 1)Ended earlyNCT01183468
What this trial is testing

A Research Trial of Aralast in New Onset Diabetes (RETAIN)

Who this might be right for
Diabetes Mellitus, Type 1
National Institute of Allergy and Infectious Diseases (NIAID) 17
Early research (Phase 1)UnknownNCT05315921
What this trial is testing

Study of OsrhAAT or Placebo in Healthy Volunteers

Who this might be right for
Emphysema Secondary to Congenital AATD
Healthgen Biotechnology Corp. 48
Not applicableStudy completedNCT01676688
What this trial is testing

Safety Study of Alfalastin (Human Alpha-1 Antitrypsin) Administered at Home

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Laboratoire français de Fractionnement et de Biotechnologies 17
Not applicableTemporarily pausedNCT00571272
What this trial is testing

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Who this might be right for
Liver DiseasesAlagille SyndromeAlpha 1-Antitrypsin Deficiency
Arbor Research Collaborative for Health 1,675
Testing effectiveness (Phase 2)WithdrawnNCT03385395
What this trial is testing

Study Comparing Weekly Intravenous Administration of OctaAlpha1 With a Marketed Preparation Glassia® in Subjects With Alpha-1-antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Octapharma
Not applicableStudy completedNCT00532805
What this trial is testing

The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Medical University of South Carolina 49
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)WithdrawnNCT02900183
What this trial is testing

Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Arrowhead Pharmaceuticals
Not applicableStudy completedNCT03383939
What this trial is testing

Inhaled A1AT in Adult Stable Bronchiectasis

Who this might be right for
Bronchiectasis Adult
Hospital Universitari Vall d'Hebron Research Institute 20
Large-scale testing (Phase 3)Ended earlyNCT04204252
What this trial is testing

Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation"

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 98
Testing effectiveness (Phase 2)Active Not RecruitingNCT06405633
What this trial is testing

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Wave Life Sciences USA, Inc. 24
Not applicableNo Longer AvailableNCT03172455
What this trial is testing

Early Access Program Using Alpha 1 Antitrypsin Infusion for Patients With Steroid Refractory Acute GvHD After Hematopoietic Stem Cell Transplantation (HSCT)

Who this might be right for
Acute-graft-versus-host DiseaseSteroid Refractory Acute Graft Versus Host DiseaseGraft-versus-host-disease+5 more
Impatients N.V. trading as myTomorrows
Not applicableStudy completedNCT03470857
What this trial is testing

Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.

Who this might be right for
NeoplasmsAntioxidantsOxidative Stress+3 more
Nicolaus Copernicus University 83
Early research (Phase 1)Study completedNCT05727800
What this trial is testing

A Phase 1, First-in-human Study of VX-668

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 114
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