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Results for “Alpha 1-antitrypsin Deficiency (AATD)”

138 trials

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Showing 20 of 138 results

Large-scale testing (Phase 3)Looking for participantsNCT06165341
What this trial is testing

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 50
Not applicableStudy completedNCT00005292
What this trial is testing

Alpha1-antitrypsin Deficiency Registry

Who this might be right for
Lung DiseasesEmphysemaAlpha-1 Antitrypsin Deficiency+1 more
National Heart, Lung, and Blood Institute (NHLBI)
Large-scale testing (Phase 3)Ended earlyNCT02722304
What this trial is testing

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha1-antitrypsin Deficiency
Baxalta now part of Shire 7
Testing effectiveness (Phase 2)Ended earlyNCT04167345
What this trial is testing

Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 48
Testing effectiveness (Phase 2)Study completedNCT01669421
What this trial is testing

Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Michael Campos, MD 10
Not applicableStudy completedNCT01974830
What this trial is testing

AL1TER™: Alpha-1 Therapy, Evaluation, and Research Patient Registry

Who this might be right for
Alpha-1 Anti-trypsin Deficiency
Coram Clinical Trials 120
Not applicableEnded earlyNCT01357460
What this trial is testing

Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency

Who this might be right for
Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Heidelberg University 18
Not applicableStudy completedNCT01419158
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Alpha-1 Antitrypsin DeficiencyChronic Obstructive Pulmonary Disease
Alpha-1 Foundation 3,457
Not applicableUnknownNCT04180319
What this trial is testing

EARCO REGISTRY. History Of Patients With Alpha-1 Antitrypsin

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Hospital Universitari Vall d'Hebron Research Institute 3,000
Not applicableLooking for participantsNCT07152834
What this trial is testing

Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction

Who this might be right for
Alpha 1-antitrypsin Deficiency (AATD)
Muğla Sıtkı Koçman University 734
Large-scale testing (Phase 3)Study completedNCT02525861
What this trial is testing

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Who this might be right for
Alpha1-antitrypsin Deficiency
Baxalta now part of Shire 34
Testing effectiveness (Phase 2)WithdrawnNCT06622668
What this trial is testing

NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

Who this might be right for
Lung DiseasePulmonary DiseaseAATD+2 more
Intellia Therapeutics
Not applicableEnded earlyNCT01241942
What this trial is testing

Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability

Who this might be right for
EmphysemaChronic Obstructive Pulmonary Disease (COPD)Cystic Fibrosis+5 more
University of North Carolina, Chapel Hill 11
Not applicableUnknownNCT03285100
What this trial is testing

The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation

Who this might be right for
Emphysema or COPDAneurysmCystic Fibrosis+1 more
Canisius-Wilhelmina Hospital 30
Testing effectiveness (Phase 2)Study completedNCT05856331
What this trial is testing

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 99
Not applicableLooking for participantsNCT06505603
What this trial is testing

PiMZ Longitudinal Cohort (PiMZ Logic)

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema or COPD
Columbia University 80
Very early researchActive Not RecruitingNCT07193615
What this trial is testing

Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
RenJi Hospital 18
Not applicableNot Yet RecruitingNCT07145385
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Non-Cirrhotic Liver Cancer

Who this might be right for
Retrospective Cohort of Patients Diagnosed With HCC on Non-Cirrhotic Liver
University Hospital, Bordeaux 71
Not applicableLooking for participantsNCT05178277
What this trial is testing

Czech AATD Registry

Who this might be right for
Alpha-1-antitrypsin Deficiency
Thomayer University Hospital 300
Large-scale testing (Phase 3)Study completedNCT01217671
What this trial is testing

International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema

Who this might be right for
Emphysema
Kamada, Ltd. 168
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