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Results for “Alpha-1 Proteinase Inhibitor”

171 trials

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Showing 20 of 171 results

Testing effectiveness (Phase 2)UnknownNCT01394835
What this trial is testing

Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant Recipients

Who this might be right for
Lung TransplantationBronchiolitis Obliterable Syndrome
Rabin Medical Center 40
Large-scale testing (Phase 3)Looking for participantsNCT06165341
What this trial is testing

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 50
Testing effectiveness (Phase 2)Study completedNCT01304537
What this trial is testing

Study of the Safety and Efficacy of Intravenous Alpha-1 Antitrypsin in Type 1 Diabetes Mellitus

Who this might be right for
Type 1 Diabetes Mellitus
Kamada, Ltd. 24
Not applicableStudy completedNCT00005292
What this trial is testing

Alpha1-antitrypsin Deficiency Registry

Who this might be right for
Lung DiseasesEmphysemaAlpha-1 Antitrypsin Deficiency+1 more
National Heart, Lung, and Blood Institute (NHLBI)
Large-scale testing (Phase 3)Ended earlyNCT02722304
What this trial is testing

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha1-antitrypsin Deficiency
Baxalta now part of Shire 7
Testing effectiveness (Phase 2)Study completedNCT02614872
What this trial is testing

Study to Evaluate the Safety and Efficacy of Intravenous Glassia® Treatment in Lung Transplantation

Who this might be right for
Transplantation, Lung Rejection
Kamada, Ltd. 30
Testing effectiveness (Phase 2)Ended earlyNCT04167345
What this trial is testing

Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 48
Testing effectiveness (Phase 2)Study completedNCT01669421
What this trial is testing

Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Michael Campos, MD 10
Not applicableStudy completedNCT01974830
What this trial is testing

AL1TER™: Alpha-1 Therapy, Evaluation, and Research Patient Registry

Who this might be right for
Alpha-1 Anti-trypsin Deficiency
Coram Clinical Trials 120
Not applicableEnded earlyNCT01357460
What this trial is testing

Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency

Who this might be right for
Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Heidelberg University 18
Large-scale testing (Phase 3)Study completedNCT01370018
What this trial is testing

Therapy to Elevate CD4 Counts in HIV-1 Disease

Who this might be right for
HIV Disease
Institute for Human Genetics and Biochemistry 4
Not applicableStudy completedNCT01419158
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Alpha-1 Antitrypsin DeficiencyChronic Obstructive Pulmonary Disease
Alpha-1 Foundation 3,457
Not applicableUnknownNCT04180319
What this trial is testing

EARCO REGISTRY. History Of Patients With Alpha-1 Antitrypsin

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Hospital Universitari Vall d'Hebron Research Institute 3,000
Not applicableLooking for participantsNCT07152834
What this trial is testing

Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction

Who this might be right for
Alpha 1-antitrypsin Deficiency (AATD)
Muğla Sıtkı Koçman University 734
Large-scale testing (Phase 3)Study completedNCT02525861
What this trial is testing

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Who this might be right for
Alpha1-antitrypsin Deficiency
Baxalta now part of Shire 34
Testing effectiveness (Phase 2)WithdrawnNCT06622668
What this trial is testing

NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

Who this might be right for
Lung DiseasePulmonary DiseaseAATD+2 more
Intellia Therapeutics
Not applicableEnded earlyNCT01241942
What this trial is testing

Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability

Who this might be right for
EmphysemaChronic Obstructive Pulmonary Disease (COPD)Cystic Fibrosis+5 more
University of North Carolina, Chapel Hill 11
Not applicableUnknownNCT03285100
What this trial is testing

The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation

Who this might be right for
Emphysema or COPDAneurysmCystic Fibrosis+1 more
Canisius-Wilhelmina Hospital 30
Testing effectiveness (Phase 2)Study completedNCT05856331
What this trial is testing

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 99
Not applicableLooking for participantsNCT06505603
What this trial is testing

PiMZ Longitudinal Cohort (PiMZ Logic)

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema or COPD
Columbia University 80
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