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Results for “Alpha-1 Proteinase Inhibitor”

173 trials

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Showing 20 of 173 results

Not applicableNot Yet RecruitingNCT06029543
What this trial is testing

Permian Health Women's Lung Health Study

Who this might be right for
COPDLung Function DecreasedAlpha 1-Antitrypsin
Permian Health Lung Institute 350
Testing effectiveness (Phase 2)WithdrawnNCT06622668
What this trial is testing

NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

Who this might be right for
Lung DiseasePulmonary DiseaseAATD+2 more
Intellia Therapeutics
Post-approval studies (Phase 4)Study completedNCT01651351
What this trial is testing

GLASSIA Infusion Rate Study

Who this might be right for
Alpha1-antitrypsin DeficiencyHealthy Volunteers
Baxalta now part of Shire 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05899673
What this trial is testing

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 31
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Post-approval studies (Phase 4)Study completedNCT00670007
What this trial is testing

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Who this might be right for
EmphysemaAlpha 1-proteinase Inhibitor Deficiency
CSL Behring 140
Not applicableEnrolling By InvitationNCT06892236
What this trial is testing

Preparation of IPSC for Cell Gene Editing for the Treatment of AATD

Who this might be right for
Alpha1-antitrypsin Deficiency
Fondazione IRCCS Policlinico San Matteo di Pavia 3
Large-scale testing (Phase 3)Study completedNCT04167514
What this trial is testing

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone

Who this might be right for
Graft Versus Host Disease (GVHD)
CSL Behring 136
Not applicableUnknownNCT03802357
What this trial is testing

Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha 1-Antitrypsin Deficiency
Schön Klinik Berchtesgadener Land 30
Early research (Phase 1)Looking for participantsNCT06049082
What this trial is testing

KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Krystal Biotech, Inc. 15
Early research (Phase 1)Study completedNCT04174118
What this trial is testing

Study of DCR-A1AT in Healthy Adult Volunteers

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 30
Testing effectiveness (Phase 2)Study completedNCT01523821
What this trial is testing

Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)

Who this might be right for
Graft-Versus-Host Disease (GVHD) Acute on Chronic
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)WithdrawnNCT03385395
What this trial is testing

Study Comparing Weekly Intravenous Administration of OctaAlpha1 With a Marketed Preparation Glassia® in Subjects With Alpha-1-antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Octapharma
Not applicableEnded earlyNCT01241942
What this trial is testing

Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability

Who this might be right for
EmphysemaChronic Obstructive Pulmonary Disease (COPD)Cystic Fibrosis+5 more
University of North Carolina, Chapel Hill 11
Testing effectiveness (Phase 2)Study completedNCT04495101
What this trial is testing

Study to Evaluate the Safety and Efficacy of Prolastin in Hospitalized Subjects With COVID-19

Who this might be right for
COVID-19
Instituto Grifols, S.A. 100
Not applicableStudy completedNCT00005292
What this trial is testing

Alpha1-antitrypsin Deficiency Registry

Who this might be right for
Lung DiseasesEmphysemaAlpha-1 Antitrypsin Deficiency+1 more
National Heart, Lung, and Blood Institute (NHLBI)
Not applicableUnknownNCT04966221
What this trial is testing

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha 1-Antitrypsin Deficiency
University of Nottingham 75
Not applicableActive Not RecruitingNCT05297812
What this trial is testing

Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease

Who this might be right for
Alpha 1-Antitrypsin DeficiencyGenetic Disease
Columbia University 286
Not applicableStudy completedNCT02382367
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Dysfunction in Pulmonary Emphysema

Who this might be right for
Pulmonary Emphysema
Hospices Civils de Lyon 190
Not applicableStudy completedNCT02691611
What this trial is testing

Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
National Jewish Health 39
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