Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Alpha-1-Antitrypsin Deficiency”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableActive Not RecruitingNCT05297812
What this trial is testing

Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease

Who this might be right for
Alpha 1-Antitrypsin DeficiencyGenetic Disease
Columbia University 286
Post-approval studies (Phase 4)Study completedNCT00261833
What this trial is testing

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Who this might be right for
Alpha1-proteinase Inhibitor DeficiencyEmphysema
CSL Behring 180
Testing effectiveness (Phase 2)Study completedNCT05856331
What this trial is testing

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 99
Not applicableStudy completedNCT01832220
What this trial is testing

Genomic Research in Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1 Antitrypsin DeficiencyAATD
University of Pittsburgh 140
Not applicableLooking for participantsNCT06505603
What this trial is testing

PiMZ Longitudinal Cohort (PiMZ Logic)

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema or COPD
Columbia University 80
Testing effectiveness (Phase 2)Study completedNCT02947087
What this trial is testing

Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis

Who this might be right for
Chronic Pancreatitis
Medical University of South Carolina 48
Testing effectiveness (Phase 2)Looking for participantsNCT07227207
What this trial is testing

TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc. 72
Not applicableStudy completedNCT01676688
What this trial is testing

Safety Study of Alfalastin (Human Alpha-1 Antitrypsin) Administered at Home

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Laboratoire français de Fractionnement et de Biotechnologies 17
Not applicableLooking for participantsNCT01851642
What this trial is testing

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Who this might be right for
Alpha-1 Antitrypsin DeficiencyAAT DeficiencyAATD+1 more
University of Florida 220
Not applicableLooking for participantsNCT07715617
What this trial is testing

Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin Deficiency

Who this might be right for
Alpha-1-antitrypsin DeficiencyEmphysemaArtificial Intelligence (AI)+3 more
University Hospital, Bordeaux 230
Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Testing effectiveness (Phase 2)Study completedNCT04474197
What this trial is testing

Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

Who this might be right for
Alpha1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT05897424
What this trial is testing

Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 185
Not applicableUnknownNCT02915614
What this trial is testing

Effects of Pulmonary Rehabilitation on Skeletal Muscle in COPD Patients

Who this might be right for
Chronic Obstructive Pulmonary Disease
Schön Klinik Berchtesgadener Land 40
Testing effectiveness (Phase 2)Study completedNCT04722887
What this trial is testing

Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 17
Testing effectiveness (Phase 2)Ended earlyNCT01379469
What this trial is testing

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1-antitrypsin DeficiencyLiver Cirrhosis
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Ended earlyNCT05643495
What this trial is testing

Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 14
Testing effectiveness (Phase 2)Study completedNCT03945292
What this trial is testing

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 40
Not applicableStudy completedNCT02547532
What this trial is testing

Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Fondazione Salvatore Maugeri 100
Very early researchActive Not RecruitingNCT07193615
What this trial is testing

Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
RenJi Hospital 18
Next Page