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Results for “Alpha1 Anti-Trypsin Deficiency”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT05727800
What this trial is testing

A Phase 1, First-in-human Study of VX-668

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 114
Testing effectiveness (Phase 2)Study completedNCT02870348
What this trial is testing

Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 4
Early research (Phase 1)Study completedNCT04174118
What this trial is testing

Study of DCR-A1AT in Healthy Adult Volunteers

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 30
Testing effectiveness (Phase 2)Study completedNCT01213043
What this trial is testing

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency

Who this might be right for
EmphysemaAlpha 1-antitrypsin Deficiency (AATD)
Grifols Therapeutics LLC 30
Testing effectiveness (Phase 2)Study completedNCT02870309
What this trial is testing

Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 4
Early research (Phase 1)Ended earlyNCT02503683
What this trial is testing

An Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Who this might be right for
Antitrypsin Deficiency Liver Disease
Alnylam Pharmaceuticals 26
Not applicableStudy completedNCT03039335
What this trial is testing

The Impact of Delayed Diagnosis of Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Biocerna LLC 43
Testing effectiveness (Phase 2)Study completedNCT00263887
What this trial is testing

Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Grifols Therapeutics LLC 77
Not applicableStudy completedNCT01419158
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Alpha-1 Antitrypsin DeficiencyChronic Obstructive Pulmonary Disease
Alpha-1 Foundation 3,457
Early research (Phase 1)Study completedNCT06186492
What this trial is testing

Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Wave Life Sciences USA, Inc. 47
Not applicableWithdrawnNCT02273349
What this trial is testing

Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1-Antitrypsin DeficiencyChronic Obstructive Lung DiseaseEmphysema
University Hospital, Saarland
Testing effectiveness (Phase 2)WithdrawnNCT01183455
What this trial is testing

A Research Trial of Aralast NP in New Onset Diabetes (RETAIN) - Part II

Who this might be right for
Diabetes Mellitus, Type 1
National Institute of Allergy and Infectious Diseases (NIAID)
Large-scale testing (Phase 3)Looking for participantsNCT05677971
What this trial is testing

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 160
Not applicableEnded earlyNCT01241942
What this trial is testing

Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability

Who this might be right for
EmphysemaChronic Obstructive Pulmonary Disease (COPD)Cystic Fibrosis+5 more
University of North Carolina, Chapel Hill 11
Very early researchStudy completedNCT00377416
What this trial is testing

Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Massachusetts, Worcester 12
Not applicableNot Yet RecruitingNCT07707635
What this trial is testing

IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel Syndrome

Who this might be right for
Irritable Bowel Syndrome (IBS)
Ariel University 150
Not applicableStudy completedNCT00001462
What this trial is testing

Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

Who this might be right for
EmphysemaLung Diseases, ObstructiveAlpha 1-Antitrypsin Deficiency
National Heart, Lung, and Blood Institute (NHLBI) 60
Testing effectiveness (Phase 2)Study completedNCT03008915
What this trial is testing

Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin DeficiencyEmphysemaChronic Obstructive Pulmonary Disease
Columbia University 15
Not applicableEnded earlyNCT03823443
What this trial is testing

COPD Exacerbation Blood and Urine Biomarkers Study

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAcute Exacerbation CopdAlpha-1 Anti-trypsin Deficiency
Columbia University 7
Not applicableLooking for participantsNCT06505603
What this trial is testing

PiMZ Longitudinal Cohort (PiMZ Logic)

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema or COPD
Columbia University 80
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