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Results for “Alzheimer's Disease in Down Syndrome”

29 trials

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Showing 20 of 29 results

Not applicableUnknownNCT03942341
What this trial is testing

Sleep in Adults With Down Syndrome and Alzheimer's Disease

Who this might be right for
Alzheimer's DiseaseObstructive Sleep ApneaSleep Disturbances
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 90
Post-approval studies (Phase 4)Not Yet RecruitingNCT06911944
What this trial is testing

Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation

Who this might be right for
Down Syndrome (DS)Down Syndrome (Trisomy 21)Alzheimer Disease+1 more
Michael Rafii, MD, PhD 60
Not applicableLooking for participantsNCT05196984
What this trial is testing

Gamma Frequency Stimulation in Individuals With Down Syndrome

Who this might be right for
Down Syndrome
Massachusetts Institute of Technology 60
Early research (Phase 1)Not Yet RecruitingNCT07278492
What this trial is testing

NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome

Who this might be right for
Down Syndrome (DS)
Brigham and Women's Hospital 24
Not applicableLooking for participantsNCT03233646
What this trial is testing

Retinal Imaging in Neurodegenerative Disease

Who this might be right for
Alzheimer's DiseaseMild Cognitive ImpairmentParkinson's Disease+12 more
Duke University 2,000
Not applicableLooking for participantsNCT05985486
What this trial is testing

Brain Outcomes With Lifestyle Change in Down Syndrome

Who this might be right for
Down SyndromeAlzheimer DiseaseObesity
University of Kansas Medical Center 81
Large-scale testing (Phase 3)Ended earlyNCT06860373
What this trial is testing

LIFE-DSR-Biomarker Sub-study of Biomarkers in Down Syndrome Related Alzheimer's Disease (DS-AD)

Who this might be right for
Down Syndrome
LuMind IDSC Foundation 5
Early research (Phase 1)Ended earlyNCT06673069
What this trial is testing

Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD)

Who this might be right for
Alzheimer DiseaseDown Syndrome
Ionis Pharmaceuticals, Inc. 1
Large-scale testing (Phase 3)UnknownNCT00056329
What this trial is testing

Vitamin E in Aging Persons With Down Syndrome

Who this might be right for
Down SyndromeAlzheimer Disease
New York State Institute for Basic Research 350
Not applicableStudy completedNCT02759887
What this trial is testing

Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)

Who this might be right for
Down SyndromeAlzheimer's Dementia
St. Joseph's Hospital and Medical Center, Phoenix 19
Testing effectiveness (Phase 2)Looking for participantsNCT05462106
What this trial is testing

Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Who this might be right for
Amyloid PlaqueBeta-AmyloidDSAD+2 more
AC Immune SA 304
Not applicableLooking for participantsNCT06740162
What this trial is testing

Physical Activity and Community EmPOWERment Project

Who this might be right for
Intellectual DisabilityNeurodevelopmental DisordersAutism Spectrum Disorder+10 more
University of North Carolina, Chapel Hill 376
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07636811
What this trial is testing

Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

Who this might be right for
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Alnylam Pharmaceuticals 58
Not applicableStudy completedNCT02141971
What this trial is testing

Down Syndrome Biomarker Initiative (DSBI)

Who this might be right for
Down SyndromeAlzheimer's Disease
Michael Rafii 12
Early research (Phase 1)Looking for participantsNCT06206824
What this trial is testing

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease

Who this might be right for
Healthy VolunteersDown SyndromeAlzheimer's Disease
Perha Pharmaceuticals 164
Not applicableEnded earlyNCT04149197
What this trial is testing

Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome

Who this might be right for
Alzheimer's Disease in Down Syndrome
LuMind IDSC Foundation 252
Large-scale testing (Phase 3)Study completedNCT01594346
What this trial is testing

Multicenter Vitamin E Trial in Aging Persons With Down Syndrome

Who this might be right for
Alzheimer's DiseaseDown Syndrome
New York State Institute for Basic Research 349
Not applicableStudy completedNCT06484426
What this trial is testing

Goal Attainment Scaling (GAS) Sub-Study

Who this might be right for
Alzheimer's Disease in Down Syndrome
LuMind IDSC Foundation 46
Not applicableEnded earlyNCT00001178
What this trial is testing

Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders

Who this might be right for
Alzheimer's DiseaseDementiaDown's Syndrome
National Institute of Neurological Disorders and Stroke (NINDS) 597
Not applicableUnknownNCT00966017
What this trial is testing

Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia

Who this might be right for
Down SyndromeAlzheimer's Disease
National Institute on Aging (NIA) 108
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