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Results for “Amyloid Cardiomyopathy, Transthyretin-Related”

81 trials

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Showing 20 of 81 results

Not applicableStudy completedNCT03588468
What this trial is testing

Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological Study

Who this might be right for
Amyloid NeuropathiesTransthyretin Amyloidosis
Assistance Publique Hopitaux De Marseille 60
Not applicableStudy completedNCT04276220
What this trial is testing

Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery

Who this might be right for
Transthyretin AmyloidosisTransthyretin Cardiac AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis
Steen Hvitfeldt Poulsen 109
Not applicableStudy completedNCT06414746
What this trial is testing

Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia

Who this might be right for
Hereditary Transthyretin AmyloidosisCarpal Tunnel SyndromePolyneuropathy+1 more
AstraZeneca 721
Early research (Phase 1)Study completedNCT05201911
What this trial is testing

Characterize the Biodistribution of 124I-Labeled AT-03 in Patients With Systemic Amyloidosis

Who this might be right for
Amyloidosis; Systemic
Attralus, Inc. 13
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableLooking for participantsNCT06291805
What this trial is testing

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more
Steen Hvitfeldt Poulsen 120
Post-approval studies (Phase 4)Active Not RecruitingNCT05489523
What this trial is testing

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Who this might be right for
Transthyretin Cardiac Amyloidosis
University of Texas Southwestern Medical Center 25
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableActive Not RecruitingNCT05873868
What this trial is testing

Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran

Who this might be right for
Transthyretin AmyloidosisAmyloidosis, Hereditary
Rennes University Hospital 20
Not applicableNot Yet RecruitingNCT06921408
What this trial is testing

Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

Who this might be right for
Cardiac AmyloidosisTransthyretin Amyloidosis
University Hospital, Lille 57
Large-scale testing (Phase 3)Looking for participantsNCT06128629
What this trial is testing

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics 1,200
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Post-approval studies (Phase 4)UnknownNCT04963985
What this trial is testing

The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients

Who this might be right for
Transthyretin Amyloidosis
Peking University Third Hospital 10
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Not applicableStudy completedNCT03352089
What this trial is testing

Positron Emission Tomography / Magnetic Resonance Imaging in Aortic Stenosis

Who this might be right for
Aortic StenosisTransthyretin Amyloidosis
University of Edinburgh 22
Large-scale testing (Phase 3)Study completedNCT03759379
What this trial is testing

HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

Who this might be right for
Amyloidosis, HereditaryTransthyretin Amyloidosis
Alnylam Pharmaceuticals 164
Not applicableEnrolling By InvitationNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableStudy completedNCT04201418
What this trial is testing

Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Who this might be right for
Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy
Alnylam Pharmaceuticals 67
Not applicableActive Not RecruitingNCT04850105
What this trial is testing

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 202
Not applicableStudy completedNCT05139680
What this trial is testing

Examine the Clinical Effectiveness of Tafamidis in Patients With Mixed Phenotype Hereditary Transthyretin Amyloidosis

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv) Cardiomyopathy (CM), Mixed Phenotype
Pfizer 10
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