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Results for “Amyloid Cardiomyopathy, Transthyretin-Related”

78 trials

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Showing 20 of 78 results

Not applicableLooking for participantsNCT07196839
What this trial is testing

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
University of Texas Southwestern Medical Center 50
Not applicableLooking for participantsNCT04850105
What this trial is testing

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 240
Not applicableLooking for participantsNCT07644325
What this trial is testing

Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy

Who this might be right for
Carpal TunnelTransthyretin Amyloidosis
Clinique Saint Jean, France 500
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableUnknownNCT05196594
What this trial is testing

Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis

Who this might be right for
Amyloidosis, Hereditary, Transthyretin-RelatedMicrobial Colonization
University of Sao Paulo General Hospital 60
Testing effectiveness (Phase 2)Study completedNCT01171859
What this trial is testing

Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 40
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Not applicableStudy completedNCT05075798
What this trial is testing

Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis Patients

Who this might be right for
Transthyretin Amyloidosis
Centre Hospitalier Universitaire de Nīmes 36
Large-scale testing (Phase 3)Looking for participantsNCT06563895
What this trial is testing

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more
Eidos Therapeutics, a BridgeBio company 587
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Early research (Phase 1)Study completedNCT05374564
What this trial is testing

Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy

Who this might be right for
Cardiomyopathies, Primary
Yale University 12
Not applicableStudy completedNCT03431896
What this trial is testing

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

Who this might be right for
AmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more
The Cleveland Clinic 37
Very early researchStudy completedNCT05023889
What this trial is testing

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Who this might be right for
PolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more
Austin Neuromuscular Center 10
Post-approval studies (Phase 4)UnknownNCT04963985
What this trial is testing

The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients

Who this might be right for
Transthyretin Amyloidosis
Peking University Third Hospital 10
Not applicableStudy completedNCT06261216
What this trial is testing

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Amyloid CardiomyopathyWild Type ATTR Amyloidosis
Medical University of Graz 180
Large-scale testing (Phase 3)Study completedNCT03997383
What this trial is testing

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 360
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableStudy completedNCT03923920
What this trial is testing

Screening for Systemic Amyloidosis Via the Ligamentum Flavum

Who this might be right for
AmyloidAmyloidosisSpinal Stenosis+2 more
The Cleveland Clinic 200
Not applicableStudy completedNCT05560555
What this trial is testing

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy
Pfizer 5
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