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Results for “Amyloid Transthyretin Cardiomyopathy”

107 trials

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Showing 20 of 107 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06194825
What this trial is testing

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
AstraZeneca 64
Early research (Phase 1)Study completedNCT04601051
What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Testing effectiveness (Phase 2)Active Not RecruitingNCT06260709
What this trial is testing

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S 80
Not applicableActive Not RecruitingNCT06393465
What this trial is testing

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 50
Testing effectiveness (Phase 2)Study completedNCT02292186
What this trial is testing

A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

Who this might be right for
TTR-mediated Amyloidosis
Alnylam Pharmaceuticals 25
Not applicableLooking for participantsNCT06907186
What this trial is testing

An Interventional Pilot Study to Investigate the Feasibility and Acceptance of a Structured Psychological Support Program for Patients, Caregivers, and Presymptomatic Carriers in Hereditary Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Hereditary Transthyretin Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT07213583
What this trial is testing

Study of Re-Treatment With ALXN2220 in Patients With ATTR-CM

Who this might be right for
Amyloid Transthyretin Cardiomyopathy
Neurimmune AG 35
Not applicableUnknownNCT05210010
What this trial is testing

A Prospective Study to Assess the Utility of CA-4F in a Canadian Cardiology Setting

Who this might be right for
Transthyretin Amyloid Cardiomyopathy ("ATTR-CM")
Ensho Health Intelligent Systems Inc. 8
Not applicableStudy completedNCT03812172
What this trial is testing

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations

Who this might be right for
Amyloid Cardiomyopathy, Transthyretin-Related
Mathew S. Maurer, MD 646
Large-scale testing (Phase 3)Active Not RecruitingNCT06128629
What this trial is testing

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics 1,200
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Not applicableLooking for participantsNCT07235462
What this trial is testing

Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Bayer 2,000
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableActive Not RecruitingNCT06257485
What this trial is testing

Bronx Transthyretin Amyloid Cardiomyopathy Database

Who this might be right for
Transthyretin Cardiac AmyloidosisTransthyretin Amyloid Cardiomyopathy
Montefiore Medical Center 476
Not applicableEnded earlyNCT04424914
What this trial is testing

Global Prevalence of ATTR-CM in Participants With HFpEF

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure With Preserved Ejection Fraction
Pfizer 347
Testing effectiveness (Phase 2)Looking for participantsNCT06634108
What this trial is testing

Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 20
Not applicableNo Longer AvailableNCT05505838
What this trial is testing

Expanded Access Protocol to Provide Patisiran to Patients With Transthyretin-mediated Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin-mediated Amyloidosis With CardiomyopathyATTR Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
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