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Results for “Amyotrophic Lateral Sclerosis (Healthy Volunteers)”

24 trials

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Showing 20 of 24 results

Not applicableStudy completedNCT00023075
What this trial is testing

Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis

Who this might be right for
Primary Lateral SclerosisHereditary Spastic ParaplegiaAmyotrophic Lateral Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS) 55
Early research (Phase 1)Study completedNCT06286475
What this trial is testing

VRG50635 in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Verge Genomics 22
Early research (Phase 1)Enrolling By InvitationNCT06782958
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)
Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. 72
Early research (Phase 1)Study completedNCT03876002
What this trial is testing

Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET

Who this might be right for
Healthy VolunteersAmyotrophic Lateral Sclerosis
Molecular NeuroImaging 23
Early research (Phase 1)Not Yet RecruitingNCT04667013
What this trial is testing

A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of TBN

Who this might be right for
Healthy
Guangzhou Magpie Pharmaceuticals Co., Ltd. 16
Early research (Phase 1)Study completedNCT06769620
What this trial is testing

A First in Human Study of ORT247 in Healthy Volunteers

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)
Orthogonal Neuroscience Inc. 44
Not applicableStudy completedNCT02236897
What this trial is testing

PET Imaging in ALS Patients

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)
Johns Hopkins University 36
Testing effectiveness (Phase 2)Looking for participantsNCT05395624
What this trial is testing

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)Parkinson Disease (PD)Alzheimer Disease (AD)+1 more
Ashvattha Therapeutics, Inc. 65
Early research (Phase 1)Study completedNCT01449578
What this trial is testing

Dexpramipexole SAD/MAD Study

Who this might be right for
Amyotrophic Lateral Sclerosis
Knopp Biosciences 63
Not applicableUnknownNCT03545451
What this trial is testing

Neurofeedback Rehabilitation Based on Motor Imaging in Patients in the Immobilization Phase

Who this might be right for
Healthy Subjects, Patients With Amyotrophic Lateral Sclerosis, Patients With Shoulder Surgery
Assistance Publique - Hôpitaux de Paris 30
Early research (Phase 1)Study completedNCT01511029
What this trial is testing

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

Who this might be right for
Amyotrophic Lateral Sclerosis
Knopp Biosciences 68
Not applicableStudy completedNCT00334516
What this trial is testing

Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

Who this might be right for
Cerebral Cortex Dysfunction
National Institute of Neurological Disorders and Stroke (NINDS) 77
Early research (Phase 1)Study completedNCT01424176
What this trial is testing

Dexpramipexole Renal PK Study

Who this might be right for
Amyotrophic Lateral SclerosisRenal Insufficiency
Knopp Biosciences 36
Early research (Phase 1)Study completedNCT05797701
What this trial is testing

A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fasted Condition Versus as a Tablet After Food (Part 2)

Who this might be right for
Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Sanofi 18
Early research (Phase 1)Study completedNCT05797753
What this trial is testing

Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)

Who this might be right for
Amyotrophic Lateral SclerosisHealthy Volunteer
Sanofi 16
Early research (Phase 1)Active Not RecruitingNCT05974579
What this trial is testing

Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
Université de Sherbrooke 12
Early research (Phase 1)Not Yet RecruitingNCT05880563
What this trial is testing

Investigation of Cannabinoid 2-receptor Expression in the Brain and Spine of ALS-patients Compared to Healthy Controls With PET (18F-RoSMALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Markus Weber 30
Early research (Phase 1)Active Not RecruitingNCT03651349
What this trial is testing

To Determine the Maximum Tolerated Dose (MTD) of HK-001 in Healthy Volunteers

Who this might be right for
Amyotrophic Lateral Sclerosis
Everfront Biotech Co., Ltd. 56
Early research (Phase 1)Study completedNCT03954600
What this trial is testing

Assess the Safety, Tolerability and PK of NPT520-34 in Healthy Subjects

Who this might be right for
Healthy Volunteers
Neuropore Therapies Inc. 49
Early research (Phase 1)Study completedNCT05795907
What this trial is testing

Single & Multiple Ascending Dose Study of SAR443820 in Healthy Adult Participants

Who this might be right for
Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Sanofi 84
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