Early research (Phase 1)Study completedNCT01424176What this trial is testingDexpramipexole Renal PK StudyWho this might be right forAmyotrophic Lateral SclerosisRenal Insufficiency Knopp Biosciences 36
Not applicableStudy completedNCT00334516What this trial is testingBrain Function in Primary Lateral Sclerosis and Amyotrophic Lateral SclerosisWho this might be right forCerebral Cortex Dysfunction National Institute of Neurological Disorders and Stroke (NINDS) 77
Early research (Phase 1)Study completedNCT01511029What this trial is testingStudy to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)Who this might be right forAmyotrophic Lateral Sclerosis Knopp Biosciences 68
Early research (Phase 1)Study completedNCT05974579What this trial is testingSafety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis Université de Sherbrooke 8
Testing effectiveness (Phase 2)Looking for participantsNCT05395624What this trial is testingSafety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy VolunteersWho this might be right forAmyotrophic Lateral Sclerosis (ALS)Parkinson Disease (PD)Alzheimer Disease (AD)+1 more Ashvattha Therapeutics, Inc. 65
Early research (Phase 1)Active Not RecruitingNCT05279755What this trial is testingEvaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALSWho this might be right forAmyotrophic Lateral Sclerosis ProJenX 72
Early research (Phase 1)Not Yet RecruitingNCT05880563What this trial is testingInvestigation of Cannabinoid 2-receptor Expression in the Brain and Spine of ALS-patients Compared to Healthy Controls With PET (18F-RoSMALS)Who this might be right forAmyotrophic Lateral Sclerosis Markus Weber 30
Early research (Phase 1)Study completedNCT01536249What this trial is testingDexpramipexole and Cimetidine Drug Drug Interaction (DDI)Who this might be right forAmyotrophic Lateral Sclerosis Knopp Biosciences 14
Early research (Phase 1)Study completedNCT03876002What this trial is testingEvaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PETWho this might be right forHealthy VolunteersAmyotrophic Lateral Sclerosis Molecular NeuroImaging 23
Early research (Phase 1)Study completedNCT01449578What this trial is testingDexpramipexole SAD/MAD StudyWho this might be right forAmyotrophic Lateral Sclerosis Knopp Biosciences 63
Early research (Phase 1)Not Yet RecruitingNCT04667013What this trial is testingA Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of TBNWho this might be right forHealthy Guangzhou Magpie Pharmaceuticals Co., Ltd. 16
Early research (Phase 1)Study completedNCT05795907What this trial is testingSingle & Multiple Ascending Dose Study of SAR443820 in Healthy Adult ParticipantsWho this might be right forAmyotrophic Lateral Sclerosis (Healthy Volunteers) Sanofi 84
Early research (Phase 1)Active Not RecruitingNCT03651349What this trial is testingTo Determine the Maximum Tolerated Dose (MTD) of HK-001 in Healthy VolunteersWho this might be right forAmyotrophic Lateral Sclerosis Everfront Biotech Co., Ltd. 56
Early research (Phase 1)Study completedNCT05797753What this trial is testingAssess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)Who this might be right forAmyotrophic Lateral SclerosisHealthy Volunteer Sanofi 16
Early research (Phase 1)Study completedNCT05882695What this trial is testingStudy of SPG302 in Healthy Volunteers and ALS ParticipantsWho this might be right forAmyotrophic Lateral Sclerosis Spinogenix 88
Not applicableStudy completedNCT00023075What this trial is testingNuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral SclerosisWho this might be right forPrimary Lateral SclerosisHereditary Spastic ParaplegiaAmyotrophic Lateral Sclerosis National Institute of Neurological Disorders and Stroke (NINDS) 55
Early research (Phase 1)Study completedNCT06286475What this trial is testingVRG50635 in Healthy VolunteersWho this might be right forHealthy Volunteers Verge Genomics 22
Not applicableStudy completedNCT02236897What this trial is testingPET Imaging in ALS PatientsWho this might be right forAmyotrophic Lateral Sclerosis (ALS) Johns Hopkins University 36
Not applicableUnknownNCT03545451What this trial is testingNeurofeedback Rehabilitation Based on Motor Imaging in Patients in the Immobilization PhaseWho this might be right forHealthy Subjects, Patients With Amyotrophic Lateral Sclerosis, Patients With Shoulder Surgery Assistance Publique - Hôpitaux de Paris 30
Not applicableStudy completedNCT00809224What this trial is testingCortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)Who this might be right forALSAmyotrophic Lateral Sclerosis University of Michigan 92