Large-scale testing (Phase 3)Ended earlyNCT06111014What this trial is testingContinuation Study for LatozinemabWho this might be right forNeurodegenerative Diseases Alector Inc. 17
Not applicableLooking for participantsNCT06595212What this trial is testingGenetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics ApproachWho this might be right forALSFTD Azienda Ospedaliero-Universitaria di Modena 45
Not applicableUnknownNCT06072287What this trial is testingThe Living With a Long-Term Condition StudyWho this might be right forAsthmaAtrial FibrillationCancer+42 more King's College London 600
Not applicableLooking for participantsNCT04363684What this trial is testingARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Who this might be right forFrontotemporal Lobar Degeneration (FTLD)Progressive Supranuclear Palsy (PSP)Corticobasal Degeneration (CBD)+11 more Mayo Clinic 2,100
Not applicableWithdrawnNCT04055532What this trial is testingBiomarkers in Neurodegenerative DiseasesWho this might be right forMild Cognitive Impairment (MCI)Alzheimer Disease (AD)Dementia With Lewy Bodies (DLB)+8 more University of Minnesota
Not applicableLooking for participantsNCT06528964What this trial is testingProteinopathies Expression in Skin of Neurodegenerative DisordersWho this might be right forAlzheimer DiseaseFrontotemporal DementiaParkinson Disease+3 more Universidad Autonoma de San Luis Potosí 40
Testing effectiveness (Phase 2)Looking for participantsNCT05395624What this trial is testingSafety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy VolunteersWho this might be right forAmyotrophic Lateral Sclerosis (ALS)Parkinson Disease (PD)Alzheimer Disease (AD)+1 more Ashvattha Therapeutics, Inc. 65
Not applicableStudy completedNCT05852405What this trial is testingClinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALSWho this might be right forMotor Neuron Disease, Amyotrophic Lateral Sclerosis Ambulanzpartner Soziotechnologie APST GmbH 2,000
Not applicableStudy completedNCT02365922What this trial is testingAdvancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)Who this might be right forFTLDProgressive Supranuclear Palsy (PSP)Frontotemporal Dementia (FTD)+9 more University of California, San Francisco 1,489
Testing effectiveness (Phase 2)Active Not RecruitingNCT04220021What this trial is testingSafety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTDWho this might be right forC9orf72 Amyotrophic Lateral Sclerosis (ALS)Frontotemporal Dementia University of Florida 41
Testing effectiveness (Phase 2)Study completedNCT05189106What this trial is testingNeurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialWho this might be right forAmyotrophic Lateral SclerosisAlzheimer DiseaseMild Cognitive Impairment Massachusetts General Hospital 17
Testing effectiveness (Phase 2)Ended earlyNCT04931862What this trial is testingStudy of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)Who this might be right forALSFTD Wave Life Sciences Ltd. 35
Not applicableLooking for participantsNCT06596746What this trial is testingNeurodegenerative Diseases Progression Markers (MARKERS-NDD)Who this might be right forNeurodegenerative DiseasesParkinson DiseaseSynucleinopathies+15 more Casa di Cura San Raffaele Cassino 600
Not applicableLooking for participantsNCT00317616What this trial is testingThe Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) StudyWho this might be right forAmyotrophic Lateral Sclerosis University of Miami 500
Very early researchLooking for participantsNCT06891716What this trial is testing[18F]ACI-19626 PET in TDP-43 ProteinopathiesWho this might be right forFrontotemporal Dementia (FTD)Amyotrophic Lateral Sclerosis (ALS)TDP-43 Proteinopathies+2 more AC Immune SA 45
Not applicableLooking for participantsNCT07509125What this trial is testingUltra-High Resolution PET in Aging, Neurodegeneration and Psychotic DisordersWho this might be right forAlzheimer Dementia (AD)ALS - Amyotrophic Lateral SclerosisParkinson s Disease+7 more Universitaire Ziekenhuizen KU Leuven 300
Not applicableNo Longer AvailableNCT06069934What this trial is testingA Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)Who this might be right forAmyotrophic Lateral Sclerosis Prilenia
Not applicableStudy completedNCT04293484What this trial is testingCortico-Spinal tDCS as Rehabilitative Intervention in Amyotrophic Lateral SclerosisWho this might be right forMotor Neuron Disease, FamilialAmyotrophic Lateral Sclerosis With Dementia Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 31
Not applicableLooking for participantsNCT06539169What this trial is testingFLOWER: Following Longitudinal Outcomes With Epidemiology for Rare DiseasesWho this might be right forAlpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more xCures 1,000
Not applicableLooking for participantsNCT03865420What this trial is testingAmyotrophic Lateral Sclerosis (ALS) Families ProjectWho this might be right forALS Columbia University 300