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Results for “Anhedonia in Major Depressive Disorder”

44 trials

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Showing 20 of 44 results

Not applicableActive Not RecruitingNCT05841030
What this trial is testing

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

Who this might be right for
Depressive Disorder, Major
Janssen Research & Development, LLC 545
Not applicableStudy completedNCT05120336
What this trial is testing

TVNS Effects on Motivation in Depression

Who this might be right for
Major Depressive Disorder
University Hospital Tuebingen 67
Early research (Phase 1)Looking for participantsNCT05320107
What this trial is testing

The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects

Who this might be right for
Major Depressive Disorder
Medical University of Vienna 60
Not applicableNot Yet RecruitingNCT07032428
What this trial is testing

Efficacy of kTMP, a Novel Non-invasive Brain Stimulation Method, for the Treatment of Anhedonia

Who this might be right for
Anhedonia in Major Depressive Disorder
Magnetic Tides 80
Post-approval studies (Phase 4)Study completedNCT02859103
What this trial is testing

Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment

Who this might be right for
DepressionAnhedonia
Unity Health Toronto 56
Not applicableEnded earlyNCT02236702
What this trial is testing

Kappa Opioid Receptor Imaging in Depression (KOR Depression)

Who this might be right for
Major Depressive DisorderAnhedonia
NYU Langone Health 15
Not applicableLooking for participantsNCT06270433
What this trial is testing

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder

Who this might be right for
Anhedonia
Jiangsu Province Nanjing Brain Hospital 80
Large-scale testing (Phase 3)Study completedNCT05550532
What this trial is testing

Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Who this might be right for
Depressive Disorder, MajorAnhedonia
Janssen Research & Development, LLC 444
Post-approval studies (Phase 4)Study completedNCT04352101
What this trial is testing

Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits

Who this might be right for
Major Depression
Emory University 18
Large-scale testing (Phase 3)Ended earlyNCT06635135
What this trial is testing

Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

Who this might be right for
Depressive Disorder, MajorAnhedonia
Janssen Research & Development, LLC 47
Not applicableLooking for participantsNCT05909267
What this trial is testing

Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation

Who this might be right for
Depressive Disorder, Major
Charite University, Berlin, Germany 165
Not applicableEnded earlyNCT05291897
What this trial is testing

First choIce Antidepressants: General Practitioner's Treatment Approach in the Czech Republic

Who this might be right for
Major Depressive Disorder Co-Occurrent With AnxietyAdult PatientsNewly Diagnosed Depression
Angelini Pharma Česká republika s.r.o. 28
Not applicableStudy completedNCT05629520
What this trial is testing

A Neurobiological Model of Anhedonia

Who this might be right for
AnhedoniaDepression
Milton S. Hershey Medical Center 60
Not applicableStudy completedNCT04024371
What this trial is testing

Validating Reward-related Biomarkers (RTOC)

Who this might be right for
SchizophreniaDepressionMotivation+3 more
Maastricht University 160
Not applicableEnrolling By InvitationNCT06026904
What this trial is testing

The Effects of taVNS on Motivation in MDD With Anhedonia

Who this might be right for
Depression
Anhui Medical University 60
Large-scale testing (Phase 3)Study completedNCT05455684
What this trial is testing

Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Who this might be right for
Depressive Disorder, MajorAnhedonia
Janssen Research & Development, LLC 513
Testing effectiveness (Phase 2)Study completedNCT06391593
What this trial is testing

PD, PK, and Safety of ALTO-203 in Patients With MDD

Who this might be right for
Major Depressive DisorderAnhedonia
Alto Neuroscience 69
Not applicableStudy completedNCT00059579
What this trial is testing

Brain Regulation of Emotions in People With Depression and Anhedonia

Who this might be right for
Major Depressive Disorder
National Institute of Mental Health (NIMH) 163
Not applicableEnrolling By InvitationNCT07467473
What this trial is testing

Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression

Who this might be right for
Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta BurstLeft Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta BurstLeft Primary Somatosensory Cortex - Accelerated Intermittent Theta Burst
Florida State University 48
Post-approval studies (Phase 4)Looking for participantsNCT06610305
What this trial is testing

Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

Who this might be right for
Major Depressive Disorder
University of North Carolina, Chapel Hill 75
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