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Results for “Antibody-Drug Conjugate”

462 trials

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Showing 20 of 462 results

Testing effectiveness (Phase 2)Enrolling By InvitationNCT06680596
What this trial is testing

Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy

Who this might be right for
Breast Cancer MetastaticBreast Cancer Stage IV
UNICANCER 80
Early research (Phase 1)Ended earlyNCT06523803
What this trial is testing

ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers

Who this might be right for
Mesothelin-expressing Advanced Cancers
Zymeworks BC Inc. 32
Not applicableActive Not RecruitingNCT05571618
What this trial is testing

The Rechallenge of ADCs in MBC Patients

Who this might be right for
Breast Cancer
Fudan University 100
Testing effectiveness (Phase 2)Looking for participantsNCT07181161
What this trial is testing

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

Who this might be right for
Metastatic Prostate Cancer
AstraZeneca 283
Large-scale testing (Phase 3)Study completedNCT03474107
What this trial is testing

Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)

Who this might be right for
Ureteral CancerUrothelial CancerBladder Cancer
Astellas Pharma Global Development, Inc. 608
Large-scale testing (Phase 3)Not Yet RecruitingNCT07796100
What this trial is testing

ZL-1310 in Combination With a Checkpoint Inhibitor Versus Standard of Care Platinum Based Chemotherapy With a Checkpoint Inhibitor as First-line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Extensive-Stage Small Cell Lung Cancer
Zai Lab (Shanghai) Co., Ltd. 530
Early research (Phase 1)Looking for participantsNCT05948865
What this trial is testing

CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
CancerCancer, Lung
Conjupro Biotherapeutics, Inc. 132
Large-scale testing (Phase 3)Active Not RecruitingNCT05687266
What this trial is testing

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

Who this might be right for
NSCLC
AstraZeneca 1,350
Early research (Phase 1)Active Not RecruitingNCT04042701
What this trial is testing

DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer

Who this might be right for
Breast CancerNon-small Cell Lung Carcinoma
Daiichi Sankyo 115
Testing effectiveness (Phase 2)Study completedNCT06188559
What this trial is testing

BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Eisai Inc. 56
Testing effectiveness (Phase 2)Looking for participantsNCT06265727
What this trial is testing

Investigate CRB-701 in Solid Tumors

Who this might be right for
Solid Tumor, Adult
Corbus Pharmaceuticals Inc. 348
Very early researchWithdrawnNCT03473691
What this trial is testing

Pilot Study of Glembatumumab Vedotin Following Doxorubicin and Cytoxan as Neo-adjuvant Therapy in Gp-NMB-expressing High Risk Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast Cancer
University of Virginia
Testing effectiveness (Phase 2)Looking for participantsNCT06747585
What this trial is testing

Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

Who this might be right for
Squamous Non-small-cell Lung CancerHead and Neck Squamous Cell CarcinomaCervical Squamous Cell Carcinoma+1 more
Alentis Therapeutics AG 170
Testing effectiveness (Phase 2)Study completedNCT04843709
What this trial is testing

MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Lepu Biopharma Co., Ltd. 39
Early research (Phase 1)Study completedNCT01166490
What this trial is testing

Dose Escalation Trial of ASG-5ME in Pancreatic or Gastric Adenocarcinoma

Who this might be right for
Gastric NeoplasmsPancreatic Neoplasms
Seagen Inc. 51
Early research (Phase 1)Looking for participantsNCT07473726
What this trial is testing

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and PK of HLX48 in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech 72
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07686068
What this trial is testing

First-in-Human Trial of VBC106 in Participants With Advanced Solid Tumors

Who this might be right for
Participants With Advanced Solid Tumor Malignancies
VelaVigo Bio Inc 260
Early research (Phase 1)Looking for participantsNCT07223125
What this trial is testing

JNJ-89862175 for Treatment of Advanced Solid Tumors

Who this might be right for
Advanced-stage Solid Tumors
Janssen Research & Development, LLC 360
Testing effectiveness (Phase 2)UnknownNCT05338957
What this trial is testing

MRG002 in the Treatment of Patients With HER2-expressed Advanced Malignant Solid Tumors.

Who this might be right for
Advanced Malignant Solid Tumors
Shanghai Miracogen Inc. 30
Not applicableEnded earlyNCT05425550
What this trial is testing

Evaluation of the Medidux™ Digital Health Application in Patients With HER2-positive Breast Cancer.

Who this might be right for
Breast Cancer
Palleos Healthcare GmbH 196
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