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Results for “Antibody-drug Conjugates”

462 trials

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Showing 20 of 462 results

Early research (Phase 1)Study completedNCT05323045
What this trial is testing

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

Who this might be right for
Solid Tumor
Byondis B.V. 31
Testing effectiveness (Phase 2)Looking for participantsNCT07109219
What this trial is testing

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia (B-ALL)
AstraZeneca 83
Early research (Phase 1)Ended earlyNCT02512237
What this trial is testing

A Dose-escalation Study of ARX788, IV Administered in Subjects With Advanced Cancers With HER2 Expression

Who this might be right for
Breast NeoplasmsStomach Neoplasms
Zhejiang Medicine Co., Ltd. 9
Large-scale testing (Phase 3)Looking for participantsNCT05950945
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Daiichi Sankyo 250
Large-scale testing (Phase 3)Looking for participantsNCT07604766
What this trial is testing

An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in China

Who this might be right for
Platinum-resistant Ovarian Cancer
Genmab 82
Not applicableNot Yet RecruitingNCT07504939
What this trial is testing

Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinoma

Who this might be right for
Upper Tract Urothelial Carcinoma Receiving Kidney-sparing TherapyUpper Tract Urothelial Carcinoma
Peking University First Hospital 36
Early research (Phase 1)Ended earlyNCT02908451
What this trial is testing

AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+1 more
AbGenomics B.V Taiwan Branch 39
Testing effectiveness (Phase 2)UnknownNCT05141747
What this trial is testing

MRG002 in the Treatment of HER2-positive/HER2-low Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer.

Who this might be right for
Locally Advanced Gastric CancerMetastatic HER2 Positive Gastroesophageal Junction Cancer
Shanghai Miracogen Inc. 60
Early research (Phase 1)Ended earlyNCT04982224
What this trial is testing

Study of REGN5093-M114 (METxMET Antibody-Drug Conjugate) in Adult Patients With Mesenchymal Epithelial Transition Factor (MET) Overexpressing Advanced Cancer

Who this might be right for
Advanced NSCLC
Regeneron Pharmaceuticals 30
Testing effectiveness (Phase 2)Ended earlyNCT01605318
What this trial is testing

Study of Labetuzumab Govitecan in Participants With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerColon CancerRectal Cancer
Gilead Sciences 92
Testing effectiveness (Phase 2)Looking for participantsNCT07111520
What this trial is testing

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
BioNTech SE 880
Early research (Phase 1)Looking for participantsNCT07082920
What this trial is testing

JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Janssen Research & Development, LLC 140
Early research (Phase 1)Active Not RecruitingNCT06806046
What this trial is testing

Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors

Who this might be right for
Solid TumorsColorectal Cancer
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 12
Early research (Phase 1)Looking for participantsNCT07067567
What this trial is testing

AK146D1 for Injection in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Akeso 200
Testing effectiveness (Phase 2)Looking for participantsNCT06235216
What this trial is testing

Sacituzumab govitEcan in THYroid Cancers

Who this might be right for
Differentiated Thyroid CancerAnaplastic Thyroid Cancer
Grupo Espanol de Tumores Neuroendocrinos 42
Post-approval studies (Phase 4)Active Not RecruitingNCT06429761
What this trial is testing

Phase 4 Study to Assess the Safety of Trastuzumab Deruxtecan, in Indian Patients

Who this might be right for
BREAST CANCER
AstraZeneca 100
Early research (Phase 1)Active Not RecruitingNCT05647122
What this trial is testing

First in Human Study of AZD9592 in Solid Tumors

Who this might be right for
Advanced Solid TumoursCarcinoma Non-small Cell LungHead and Neck Neoplasms+1 more
AstraZeneca 167
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07825753
What this trial is testing

Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer

Who this might be right for
Advanced or Metastatic Pancreatic AdenocarcinomaAdvanced or Metastatic Breast Cancer (BC)
Fudan University 225
Early research (Phase 1)Looking for participantsNCT06233942
What this trial is testing

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BeOne Medicines 308
Testing effectiveness (Phase 2)Looking for participantsNCT07181161
What this trial is testing

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

Who this might be right for
Metastatic Prostate Cancer
AstraZeneca 283
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