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Results for “Antibody-drug Conjugates”

426 trials

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Showing 20 of 426 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07419880
What this trial is testing

Re-challenge Immunotherapy With Cromolyn, TQB2102, and Panpulimab in Immune-Refractory Triple Negative Breast Cancer

Who this might be right for
Triple -Negative Breast Cancer
Fudan University 46
Early research (Phase 1)Study completedNCT01969643
What this trial is testing

A Safety Study of SGN-LIV1A in Breast Cancer Patients

Who this might be right for
HER2 Positive Breast NeoplasmsHormone Receptor Positive Breast NeoplasmsTriple Negative Breast Neoplasms+1 more
Seagen Inc. 290
Early research (Phase 1)Study completedNCT02216890
What this trial is testing

Safety Study of SGN-CD70A in Cancer Patients

Who this might be right for
Renal Cell CarcinomaMantle-Cell LymphomaDiffuse, Large B-Cell, Lymphoma+1 more
Seagen Inc. 38
Testing effectiveness (Phase 2)WithdrawnNCT06545617
What this trial is testing

A Clinical Study to Observe How Well That BAT8006 Works on Patients With Platinum Resistance Ovarian Cancer

Who this might be right for
Platinum-resistant Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Bio-Thera Solutions
Post-approval studies (Phase 4)Looking for participantsNCT06429761
What this trial is testing

Phase 4 Study to Assess the Safety of Trastuzumab Deruxtecan, in Indian Patients

Who this might be right for
BREAST CANCER
AstraZeneca 100
Early research (Phase 1)Looking for participantsNCT07470853
What this trial is testing

MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

Who this might be right for
PROCPlatinum Resistant Ovarian CancerEndometrial Cancer
Whitehawk Therapeutics, Inc. 265
Large-scale testing (Phase 3)Study completedNCT04296890
What this trial is testing

Mirvetuximab Soravtansine in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression

Who this might be right for
Epithelial Ovarian CancerPeritoneal CancerFallopian Tube Cancer
ImmunoGen, Inc. 106
Early research (Phase 1)Looking for participantsNCT06400472
What this trial is testing

LY4170156 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsUterine Cervical Neoplasms+4 more
Eli Lilly and Company 495
Testing effectiveness (Phase 2)Looking for participantsNCT07093970
What this trial is testing

MRG006A in the Treatment of Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Lepu Biopharma Co., Ltd. 343
Large-scale testing (Phase 3)Active Not RecruitingNCT05374512
What this trial is testing

Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Who this might be right for
Breast Cancer
AstraZeneca 644
Large-scale testing (Phase 3)Active Not RecruitingNCT04595565
What this trial is testing

Sacituzumab Govitecan in Primary HER2-negative Breast Cancer

Who this might be right for
HER2-negative Breast CancerTriple Negative Breast Cancer
GBG Forschungs GmbH 1,332
Early research (Phase 1)Study completedNCT01475006
What this trial is testing

AMG 595 First-in-Human in Recurrent Gliomas

Who this might be right for
Advanced Malignant GliomaAnaplastic AstrocytomasGlioblastoma Multiforme
Amgen 32
Large-scale testing (Phase 3)Active Not RecruitingNCT06619236
What this trial is testing

Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer

Who this might be right for
Platinum-resistant Ovarian Cancer
Genmab 530
Testing effectiveness (Phase 2)UnknownNCT05115500
What this trial is testing

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Who this might be right for
CarcinomaSolid Tumor
Second Affiliated Hospital of Soochow University 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT06057922
What this trial is testing

A Study YL201 in Patients With Selected Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
MediLink Therapeutics (Suzhou) Co., Ltd. 990
Early research (Phase 1)Active Not RecruitingNCT04042701
What this trial is testing

DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer

Who this might be right for
Breast CancerNon-small Cell Lung Carcinoma
Daiichi Sankyo 115
Large-scale testing (Phase 3)Study completedNCT02573324
What this trial is testing

ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification

Who this might be right for
GlioblastomaGliosarcoma
AbbVie 691
Large-scale testing (Phase 3)Looking for participantsNCT06340568
What this trial is testing

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Who this might be right for
Endometrial Cancer
BioNTech SE 480
Early research (Phase 1)Looking for participantsNCT07164313
What this trial is testing

ZW251 in Participants With Advanced Solid Tumors

Who this might be right for
Hepatocellular CarcinomaSquamous Cell Non-Small Cell Lung CancerGerm Cell Tumor
Zymeworks BC Inc. 100
Early research (Phase 1)Looking for participantsNCT07374848
What this trial is testing

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

Who this might be right for
Solid TumorsSarcomas
Zai Lab (Shanghai) Co., Ltd. 180
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