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Results for “Antibody-drug Conjugates”

392 trials

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Showing 20 of 392 results

Early research (Phase 1)Active Not RecruitingNCT05174637
What this trial is testing

FDA018-ADC in Patients With Advanced Solid Tumors

Who this might be right for
Advanced/ Metastatic Solid Tumors
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 78
Testing effectiveness (Phase 2)Looking for participantsNCT06362252
What this trial is testing

I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Who this might be right for
Extensive Stage-small Cell Lung Cancer
Daiichi Sankyo 123
Testing effectiveness (Phase 2)Looking for participantsNCT04724018
What this trial is testing

Sacituzumab Govitecan Plus EV in Metastatic UC

Who this might be right for
Urothelial CancerMetastatic Urothelial CarcinomaMetastatic Urothelial Carcinoma of the Renal Pelvis and Ureter+1 more
Dana-Farber Cancer Institute 106
Early research (Phase 1)Ended earlyNCT06457997
What this trial is testing

PHN-010 in Patients With Advanced Solid Tumors

Who this might be right for
Lung CancerColon CancerEndometrial Cancer+4 more
Pheon Therapeutics 26
Early research (Phase 1)Looking for participantsNCT06244485
What this trial is testing

Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

Who this might be right for
Advanced Solid Tumor
Daiichi Sankyo 210
Early research (Phase 1)Looking for participantsNCT06041516
What this trial is testing

Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas

Who this might be right for
Neuroendocrine CarcinomasNeuroendocrine TumorsCarcinoma, Neuroendocrine+2 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07407933
What this trial is testing

YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

Who this might be right for
Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
MediLink Therapeutics (Suzhou) Co., Ltd. 118
Testing effectiveness (Phase 2)Ended earlyNCT02592876
What this trial is testing

Treatment Study of Denintuzumab Mafodotin (SGN-CD19A) Plus RICE Versus RICE Alone for Diffuse Large B-Cell Lymphoma

Who this might be right for
Lymphoma, B-cellLymphoma, Large B-Cell, DiffuseLymphoma, Follicular, Grade 3b+1 more
Seagen Inc. 81
Testing effectiveness (Phase 2)Study completedNCT03657043
What this trial is testing

Weekly Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With Safety Run-in (innovaTV 208)

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Cancer
Seagen Inc. 98
Large-scale testing (Phase 3)Active Not RecruitingNCT03529110
What this trial is testing

DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

Who this might be right for
Breast Cancer
Daiichi Sankyo 524
Early research (Phase 1)WithdrawnNCT05692908
What this trial is testing

An Open-Label Study of the Safety of an Anti-CD38 Antibody Drug Conjugate (STI-6129) in Patients With AL Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Sorrento Therapeutics, Inc.
Testing effectiveness (Phase 2)Study completedNCT00947856
What this trial is testing

A Brentuximab Vedotin Trial for Patients Who Have Previously Participated in a Brentuximab Vedotin Study

Who this might be right for
Disease, HodgkinLymphoma, Large-Cell, AnaplasticLymphoma, Non-Hodgkin
Seagen Inc. 110
Large-scale testing (Phase 3)Active Not RecruitingNCT04639986
What this trial is testing

Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)

Who this might be right for
Metastatic Breast Cancer
Gilead Sciences 331
Testing effectiveness (Phase 2)Study completedNCT05041257
What this trial is testing

Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Who this might be right for
Ovarian CancerPeritoneal CancerFallopian Tube Cancer
AbbVie 79
Testing effectiveness (Phase 2)Looking for participantsNCT07147348
What this trial is testing

A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 375
Early research (Phase 1)Ended earlyNCT03449030
What this trial is testing

TAK-164 in Participants With Advanced Gastrointestinal (GI) Cancer Expressing Guanylyl Cyclase C (GCC)

Who this might be right for
Gastrointestinal Neoplasms; Esophageal, Stomach, Pancreas, Colon Neoplasms; Malignant Tumors of Digestive Organ; Advanced Gastrointestinal Malignancies
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Ended earlyNCT04441099
What this trial is testing

NBE-002 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced CancerTriple Negative Breast Cancer
NBE-Therapeutics AG 12
Testing effectiveness (Phase 2)Study completedNCT02552121
What this trial is testing

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Who this might be right for
Ovary CancerCervix CancerEndometrium Cancer+4 more
Seagen Inc. 33
Early research (Phase 1)UnknownNCT05276609
What this trial is testing

ARTEMIS-001: Phase 1 Study of the HS-20093 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Hansoh Biomedical Co., Ltd 177
Not applicableEnded earlyNCT05425550
What this trial is testing

Evaluation of the Medidux™ Digital Health Application in Patients With HER2-positive Breast Cancer.

Who this might be right for
Breast Cancer
Palleos Healthcare GmbH 196
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