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Results for “Anticoagulant Reversal”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Study completedNCT02206100
What this trial is testing

PK and PD of Single, Escalating Doses of PER977 Following Enoxaparin

Who this might be right for
Healthy
Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 40
Large-scale testing (Phase 3)Study completedNCT02831660
What this trial is testing

CU Programme of Idarucizumab for Japanese Patients

Who this might be right for
Hemorrhage
Boehringer Ingelheim 1
Not applicableStudy completedNCT01722786
What this trial is testing

Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists

Who this might be right for
Severe BleedingUrgent Surgery
Cardioangiologisches Centrum Bethanien 272
Early research (Phase 1)Ended earlyNCT00770718
What this trial is testing

Factor VII, Prothrombin Complex Concentrate, and Fresh Frozen Plasma in Warfarin-Related Intracranial Hemorrhage

Who this might be right for
Intracranial Hemorrhage
University of Utah 2
Post-approval studies (Phase 4)Study completedNCT03140631
What this trial is testing

Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial Fibrillation

Who this might be right for
Atrial FibrillationCatheter Ablation
University of Michigan 153
Early research (Phase 1)Looking for participantsNCT07024160
What this trial is testing

Phase I Study of MT1011 Injection in Healthy Subjects

Who this might be right for
Used in Patients Receiving Anticoagulant Therapy (e.g., Rivaroxaban or Apixaban, Inhibitors of Coagulation Factor Xa) Who Require Reversal of Anticoagulation
Shaanxi Micot Pharmaceutical Technology Co., Ltd. 40
Large-scale testing (Phase 3)Study completedNCT03343704
What this trial is testing

This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding

Who this might be right for
Hemorrhage
Boehringer Ingelheim 19
Large-scale testing (Phase 3)Study completedNCT02815670
What this trial is testing

Reversal Dabigatran Anticoagulant Effect With Idarucizumab

Who this might be right for
Hemorrhage
Boehringer Ingelheim 1
Post-approval studies (Phase 4)Study completedNCT01343381
What this trial is testing

Comparison of Heparin Types; Efficacy and Safety

Who this might be right for
Coronary Artery Disease
McMaster University 21
Large-scale testing (Phase 3)Study completedNCT00803101
What this trial is testing

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure

Who this might be right for
Reversal of Coagulopathy
CSL Behring 176
Post-approval studies (Phase 4)Looking for participantsNCT06429332
What this trial is testing

International Care Bundle Evaluation in Cerebral Hemorrhage Research

Who this might be right for
Intracerebral HemorrhageIntracerebral HaemorrhageIntraventricular Hemorrhage+2 more
Region Skane 3,500
Large-scale testing (Phase 3)Study completedNCT02329327
What this trial is testing

A Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)

Who this might be right for
Bleeding
Alexion Pharmaceuticals, Inc. 479
Not applicableWithdrawnNCT03537521
What this trial is testing

Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA). Focus on New Antidots

Who this might be right for
Severe BleedingUrgent Surgery
Cardioangiologisches Centrum Bethanien
Testing effectiveness (Phase 2)Study completedNCT02207257
What this trial is testing

Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With Edoxaban

Who this might be right for
Anticoagulation Reversal
Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 65
Not applicableStudy completedNCT03254147
What this trial is testing

Medical Need of OAC Reversal

Who this might be right for
Atrial Fibrillation
Boehringer Ingelheim 53,969
Post-approval studies (Phase 4)Study completedNCT01159210
What this trial is testing

Efficacy and Safety of Prothromplex Total (Prothrombin Complex Concentrate) in Oral Anticoagulant Reversal

Who this might be right for
Prothrombin Complex Factor Deficiency
Baxalta now part of Shire 61
Not applicableLooking for participantsNCT07333144
What this trial is testing

Management of Gastrointestinal Bleeding Under Direct Oral Anticoagulants

Who this might be right for
Gastrointestinal Bleeding
University Hospital, Strasbourg, France 250
Post-approval studies (Phase 4)UnknownNCT03473132
What this trial is testing

Assessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC)

Who this might be right for
AnticoagulationAnticoagulation Reversal
Brigham and Women's Hospital 50
Post-approval studies (Phase 4)Looking for participantsNCT07515664
What this trial is testing

Vitamin K for Perioperative Warfarin Management

Who this might be right for
Anticoagulant Therapy
University of Michigan 20
Large-scale testing (Phase 3)Study completedNCT00618098
What this trial is testing

Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures

Who this might be right for
Reversal of Anticoagulant Treatment
Octapharma 200
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