Post-approval studies (Phase 4)Study completedNCT01343381What this trial is testingComparison of Heparin Types; Efficacy and SafetyWho this might be right forCoronary Artery Disease McMaster University 21
Large-scale testing (Phase 3)Study completedNCT02815670What this trial is testingReversal Dabigatran Anticoagulant Effect With IdarucizumabWho this might be right forHemorrhage Boehringer Ingelheim 1
Not applicableWithdrawnNCT03537521What this trial is testingReversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA). Focus on New AntidotsWho this might be right forSevere BleedingUrgent Surgery Cardioangiologisches Centrum Bethanien
Post-approval studies (Phase 4)Looking for participantsNCT06429332What this trial is testingInternational Care Bundle Evaluation in Cerebral Hemorrhage ResearchWho this might be right forIntracerebral HemorrhageIntracerebral HaemorrhageIntraventricular Hemorrhage+2 more Region Skane 3,500
Not applicableStudy completedNCT01795781What this trial is testingAssays for and Reversal of New AnticoagulantsWho this might be right forAtrial FibrillationOsteoarthritis of the KneeOsteoarthritis of the Hip R.P.Herrmann 30
Early research (Phase 1)Study completedNCT01955720What this trial is testingSafety, Tolerability, PK and PD of BI 655075 and Establishment of BI 655075 Dose(s) Effective to Reverse Prolongation of Blood Coagulation Time by DabigatranWho this might be right forHemorrhage Boehringer Ingelheim 46
Large-scale testing (Phase 3)Study completedNCT00618098What this trial is testingStudy of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive ProceduresWho this might be right forReversal of Anticoagulant Treatment Octapharma 200
Large-scale testing (Phase 3)Study completedNCT00708435What this trial is testingEfficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant TherapyWho this might be right forBlood Coagulation DisordersAcute Major Bleeding CSL Behring 216
Post-approval studies (Phase 4)UnknownNCT01478282What this trial is testingReversal of the Antithrombotic Action of New Oral AnticoagulantsWho this might be right forThrombosisAnticoagulant-induced BleedingAnticoagulant Overdosage+1 more Gines Escolar 10
Not applicableUnknownNCT02745054What this trial is testingSafety of Oral Anticoagulants RegistryWho this might be right forBlood Coagulation Hospital Quality Foundation 1,500
Early research (Phase 1)Study completedNCT04543383What this trial is testingAssess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy ParticipantsWho this might be right forHealthy Janssen Research & Development, LLC 52
Testing effectiveness (Phase 2)UnknownNCT02463591What this trial is testingReversal of Dabigatran With Prothrombin Complex ConcentrateWho this might be right forDrug Action Reversal University Medical Center Groningen 12
Large-scale testing (Phase 3)Study completedNCT02831660What this trial is testingCU Programme of Idarucizumab for Japanese PatientsWho this might be right forHemorrhage Boehringer Ingelheim 1
Early research (Phase 1)Study completedNCT01826266What this trial is testingEffects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of EdoxabanWho this might be right forAnticoagulant ReversalReversal of Edoxaban Induced Anticoagulation Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 83
Post-approval studies (Phase 4)UnknownNCT03473132What this trial is testingAssessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC)Who this might be right forAnticoagulationAnticoagulation Reversal Brigham and Women's Hospital 50
Large-scale testing (Phase 3)Study completedNCT02740335What this trial is testingStudy of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.Who this might be right forSignificant Bleeding Risk Octapharma 208
Post-approval studies (Phase 4)Study completedNCT03140631What this trial is testingUse of Protamine for Heparin Reversal After Catheter Ablation of Atrial FibrillationWho this might be right forAtrial FibrillationCatheter Ablation University of Michigan 153
Large-scale testing (Phase 3)Study completedNCT02329327What this trial is testingA Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)Who this might be right forBleeding Alexion Pharmaceuticals, Inc. 479
Large-scale testing (Phase 3)Study completedNCT00168077What this trial is testingProthrombin Complex Concentrate for Anticoagulant ReversalWho this might be right forAcquired Coagulation Factor Deficiency CSL Behring 40
Not applicableStudy completedNCT01722786What this trial is testingReversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K AntagonistsWho this might be right forSevere BleedingUrgent Surgery Cardioangiologisches Centrum Bethanien 272