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Results for “Aplastic Anemia and Other Marrow Failure Syndrome”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Study completedNCT01044186
What this trial is testing

A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity

Who this might be right for
Transfusional Iron Overload
Novartis Pharmaceuticals 30
Testing effectiveness (Phase 2)Looking for participantsNCT03653338
What this trial is testing

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Who this might be right for
Sickle Cell AnemiaBeta-thalassemia MajorDiamond-blackfan Anemia
Paul Szabolcs 5
Large-scale testing (Phase 3)Study completedNCT00235391
What this trial is testing

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Who this might be right for
ThalassemiaSickle Cell DiseaseDiamond Blackfan Anemia+1 more
Novartis Pharmaceuticals 1,683
Post-approval studies (Phase 4)Study completedNCT00673608
What this trial is testing

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

Who this might be right for
HemoglobinopathiesMyelodysplastic SyndromesOther Inherited or Acquired Anaemia+4 more
Novartis 118
Testing effectiveness (Phase 2)Active Not RecruitingNCT00544115
What this trial is testing

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+5 more
City of Hope Medical Center 260
Testing effectiveness (Phase 2)Study completedNCT00957931
What this trial is testing

Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs

Who this might be right for
Sickle Cell DiseaseThalassemiaDiamond-Blackfan Anemia
Stanford University 6
Not applicableStudy completedNCT00900055
What this trial is testing

Research Study in Healthy Volunteers of Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma

Who this might be right for
Chronic Myeloproliferative DisordersFanconi AnemiaMultiple Myeloma and Plasma Cell Neoplasm+1 more
OHSU Knight Cancer Institute 213
Testing effectiveness (Phase 2)Looking for participantsNCT01174108
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

Who this might be right for
Severe Aplastic AnemiaMDS (Myelodysplastic Syndrome)
National Heart, Lung, and Blood Institute (NHLBI) 120
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Not applicableStudy completedNCT00521430
What this trial is testing

Donor Stem Cell Transplant After Conditioning Therapy in Treating Patients With Hematologic Cancer, Recurrent or Metastatic Solid Tumor, or Other Disease

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+3 more
Asan Medical Center 30
Not applicableStudy completedNCT01146210
What this trial is testing

Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Childhood Acute Erythroleukemia (M6)Childhood Acute Megakaryocytic Leukemia (M7)Childhood Acute Minimally Differentiated Myeloid Leukemia (M0)+15 more
Children's Oncology Group 20
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Testing effectiveness (Phase 2)Ended earlyNCT00358657
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders

Who this might be right for
Immunodeficiency SyndromeSevere Aplastic AnemiaGenetic Disorder
Fred Hutchinson Cancer Center 14
Testing effectiveness (Phase 2)Study completedNCT00997386
What this trial is testing

Reduced Intensity Allogeneic PBSCT to Treat Hematologic Malignancies and Hematopoietic Failure States

Who this might be right for
Hematologic NeoplasmsMultiple MyelomaAnemia, Aplastic+2 more
University of Arizona 16
Not applicableWithdrawnNCT00900120
What this trial is testing

Collecting and Storing Blood Samples From Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
University of Medicine and Dentistry of New Jersey
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06412497
What this trial is testing

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Who this might be right for
Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more
Masonic Cancer Center, University of Minnesota 60
Not applicableStudy completedNCT01913548
What this trial is testing

Multi-Center Study of Iron Overload: Survey Study (MCSIO)

Who this might be right for
Sickle Cell DiseaseThalassemiaDiamond-Blackfan Anemia
UCSF Benioff Children's Hospital Oakland 423
Testing effectiveness (Phase 2)Study completedNCT02224872
What this trial is testing

Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

Who this might be right for
Severe Aplastic AnemiaBone Marrow Failure Syndromes
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 18
Not applicableUnknownNCT01310959
What this trial is testing

Establishing a Data Base for Aplastic Anemia and Other Marrow Failure Syndrome

Who this might be right for
Aplastic Anemia and Other Marrow Failure Syndrome
King Faisal Specialist Hospital & Research Center 88
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