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Results for “Arginase Deficiency”

16 trials

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Enrolling by Invitation

Showing 16 of 16 results

Testing effectiveness (Phase 2)Ended earlyNCT03933410
What this trial is testing

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder

Who this might be right for
Urea Cycle Disorder
Kaleido Biosciences 13
Not applicableUnknownNCT05910151
What this trial is testing

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Who this might be right for
Propionic/Methylmalonic AcidemiasMaple Syrup Urine DiseaseCitrullinemia+26 more
West Kazakhstan Medical University 2,250
Testing effectiveness (Phase 2)Study completedNCT03378531
What this trial is testing

AEB1102 (Pegzilarginase) in Patients With Arginase I Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 14
Not applicableUnknownNCT05412160
What this trial is testing

Improving Quality of Life and Daily Life Activities With Bioarginine in Patients With COPD

Who this might be right for
COPDDyspneaArgininemia
University of Milan 152
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Study completedNCT02488044
What this trial is testing

AEB1102 in Patients With Arginase I Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 16
Large-scale testing (Phase 3)Study completedNCT03921541
What this trial is testing

Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 32
Not applicableStudy completedNCT06683820
What this trial is testing

Triple Recipient Strategy Using Split, Domino, and Auxiliary Techniques

Who this might be right for
Hepatocellular Carcinoma (HCC)
Second Affiliated Hospital, School of Medicine, Zhejiang University 3
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableLooking for participantsNCT04908319
What this trial is testing

Hepatic Histopathology in Urea Cycle Disorders

Who this might be right for
Urea Cycle DisorderOrnithine Transcarbamylase DeficiencyCitrullinemia 1+7 more
Baylor College of Medicine 70
Large-scale testing (Phase 3)Study completedNCT06582524
What this trial is testing

Pegzilarginase in Subjects <24 Months Old With Arginase 1 Deficiency

Who this might be right for
Arginase 1 Deficiency
Immedica Pharma AB 3
Not applicableEnded earlyNCT01421888
What this trial is testing

The NIH UNI Study: Urea Cycle Disorders, Nutrition and Immunity

Who this might be right for
Argininosuccinic AciduriaCarbamoyl-Phosphate Synthase I DeficiencyCitrullinemia+3 more
National Human Genome Research Institute (NHGRI) 4
Large-scale testing (Phase 3)Ended earlyNCT05676853
What this trial is testing

Safety of Weekly Subcutaneous Pegzilarginase in Subjects With Arginase 1 Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 3
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Not applicableLooking for participantsNCT04612764
What this trial is testing

Liver Disease in Urea Cycle Disorders

Who this might be right for
Urea Cycle DisorderOrnithine Transcarbamylase DeficiencyCitrullinemia 1+5 more
Baylor College of Medicine 62