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Results for “Argininosuccinate Synthase”

14 trials

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Showing 14 of 14 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07773246
What this trial is testing

Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD

Who this might be right for
Urea Cycle Disorders, InbornUrea Cycle DisordersOrnithine Transcarbamylase (OTC) Deficiency+8 more
Korro Bio, Inc. 30
Early research (Phase 1)Study completedNCT01665183
What this trial is testing

Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma

Who this might be right for
Cutaneous Melanoma, Uveal Melanoma, Ovarian Carcinoma or Other Advanced Solid Tumors
Polaris Group 8
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Early research (Phase 1)Study completedNCT02101580
What this trial is testing

Ph 1B Trial With ADI-PEG 20 Plus Nab-Paclitaxel and Gemcitabine in Subjects With Pancreatic Cancer

Who this might be right for
Advanced Pancreatic Cancer
Polaris Group 21
Early research (Phase 1)Ended earlyNCT02029690
What this trial is testing

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin

Who this might be right for
Pleural Mesothelioma Malignant AdvancedPeritoneal Mesothelioma Malignant AdvancedNon-squamous Non-small Cell Lung Carcinoma+4 more
Polaris Group 85
Not applicableEnded earlyNCT01948427
What this trial is testing

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorder
Amgen 203
Testing effectiveness (Phase 2)Study completedNCT00718627
What this trial is testing

Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders

Who this might be right for
Urea Cycle DisordersCarbamoylphosphate Synthetase I DeficiencyOrnithine Transcarbamylase Deficiency+1 more
Cytonet GmbH & Co. KG 12
Early research (Phase 1)Study completedNCT02101593
What this trial is testing

Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer

Who this might be right for
Hepatocellular Carcinoma
Polaris Group 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT04587830
What this trial is testing

ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme

Who this might be right for
Glioblastoma Multiforme (GBM)
Polaris Group 100
Testing effectiveness (Phase 2)Study completedNCT01910012
What this trial is testing

PH 2 ADI-PEG 20 Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Polaris Group 43
Testing effectiveness (Phase 2)Ended earlyNCT02102022
What this trial is testing

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Who this might be right for
Advanced Gastrointestinal (GI) MalignanciesHepatocellular CarcinomaGastric Cancer+1 more
Polaris Group 140
Testing effectiveness (Phase 2)Study completedNCT01910025
What this trial is testing

PH 2 ADI-PEG 20 Study in Non-Hodgkin's Lymphoma Subjects Who Have Failed Prior Systemic Therapy

Who this might be right for
Non-Hodgkin's Lymphoma
Polaris Group 18
Early research (Phase 1)Study completedNCT01528384
What this trial is testing

Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient

Who this might be right for
Argininosuccinate Synthetase Deficient
Polaris Group 8
Not applicableStudy completedNCT01610089
What this trial is testing

Nitric Oxide Flux and Ureagenesis in Argininosuccinate Synthetase Deficiency (ASSD)(Citrullinemia I)

Who this might be right for
Citrullinemia
Baylor College of Medicine 6