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Results for “Astrocytoma, IDH-Mutant”

47 trials

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Showing 20 of 47 results

Not applicableLooking for participantsNCT07832734
What this trial is testing

Metabolomics and Transcriptomics of Low- and High-Grade Gliomas

Who this might be right for
IDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07832123
What this trial is testing

Safusidenib for Patients With Newly Diagnosed IDH1-mutant CNS WHO Grade 3 Oligodendroglioma and Astrocytoma - a Single Arm Phase II Study

Who this might be right for
Glioma : Oligodendroglioma or Astrocytoma
University of Zurich 20
Not applicableNot Yet RecruitingNCT06368934
What this trial is testing

Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma

Who this might be right for
GliomaGlioblastoma
Huashan Hospital 326
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Not applicableStudy completedNCT07673666
What this trial is testing

GliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3)

Who this might be right for
GliomaGlioma (Diagnosis)Astrocytoma+4 more
Deep Learning Institute of Radiological Sciences 1,372
Post-approval studies (Phase 4)Study completedNCT06625047
What this trial is testing

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Who this might be right for
Astrocytoma, IDH-MutantGlioblastomaGlioma+1 more
Mayo Clinic 30
Early research (Phase 1)Looking for participantsNCT05879367
What this trial is testing

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

Who this might be right for
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme+4 more
Orbus Therapeutics, Inc. 66
Not applicableLooking for participantsNCT05190172
What this trial is testing

PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas

Who this might be right for
OligodendrogliomaOligodendroglioma, AnaplasticDiffuse Astrocytoma, IDH-Mutant
Oslo University Hospital 225
Early research (Phase 1)Looking for participantsNCT07223034
What this trial is testing

177Lu-PSMA-617 in People With Gliomas

Who this might be right for
GliomaDiffuse Astrocytoma, IDH-Wildtype (Grade 2-4)Glioblastoma, IDH-wildtype+3 more
Memorial Sloan Kettering Cancer Center 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07120984
What this trial is testing

Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma

Who this might be right for
Glioma
Philogen S.p.A. 52
Early research (Phase 1)Enrolling By InvitationNCT06896110
What this trial is testing

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Who this might be right for
Glioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more
Andrew P. Groves 34
Not applicableStudy completedNCT05375318
What this trial is testing

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels

Who this might be right for
Astrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more
Juan M Garcia-Gomez 50
Testing effectiveness (Phase 2)Looking for participantsNCT05345002
What this trial is testing

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Who this might be right for
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCE 55
Not applicableStudy completedNCT05229198
What this trial is testing

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas

Who this might be right for
Astrocytoma, Grade IV
Juan M Garcia-Gomez 300
Early research (Phase 1)Active Not RecruitingNCT03528642
What this trial is testing

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Astrocytoma, IDH-Mutant, Grade 3
National Cancer Institute (NCI) 23
Not applicableStudy completedNCT07673705
What this trial is testing

GliomaAI-Oligo: MRI-Based Detection of IDH Mutant Oligodendroglioma

Who this might be right for
GliomaGlioma (Diagnosis)Oligodendroglioma+2 more
Deep Learning Institute of Radiological Sciences 1,372
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Looking for participantsNCT07468136
What this trial is testing

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Who this might be right for
Anaplastic OligodendrogliomaAstrocytoma, IDH-Mutant, Grade 3Astrocytoma, IDH-Mutant, Grade 4+3 more
Mayo Clinic 33
Large-scale testing (Phase 3)Looking for participantsNCT05303519
What this trial is testing

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Who this might be right for
GliomaAstrocytoma, Grade IVIDH1-mutant Glioma+5 more
Nuvation Bio Inc. 365
Testing effectiveness (Phase 2)Looking for participantsNCT07831369
What this trial is testing

VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma

Who this might be right for
GlioblastomaAstrocytoma, IDH-Mutant, Grade 4
Inova Health Care Services 52
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