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Results for “Astrocytoma, IDH-Mutant”

47 trials

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Showing 20 of 47 results

Not applicableStudy completedNCT07673666
What this trial is testing

GliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3)

Who this might be right for
GliomaGlioma (Diagnosis)Astrocytoma+4 more
Deep Learning Institute of Radiological Sciences 1,372
Testing effectiveness (Phase 2)Study completedNCT02968940
What this trial is testing

Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma

Who this might be right for
Glioblastoma
NYU Langone Health 6
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableStudy completedNCT07673705
What this trial is testing

GliomaAI-Oligo: MRI-Based Detection of IDH Mutant Oligodendroglioma

Who this might be right for
GliomaGlioma (Diagnosis)Oligodendroglioma+2 more
Deep Learning Institute of Radiological Sciences 1,372
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Not applicableStudy completedNCT05393258
What this trial is testing

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

Who this might be right for
AstrocytomaOligodendroglioma, AdultGlioma, Malignant
Washington University School of Medicine 13
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Testing effectiveness (Phase 2)Looking for participantsNCT07417761
What this trial is testing

Tuvusertib in Astrocytoma With ATRX Mutation

Who this might be right for
Astrocytoma
Grupo Español de Investigación en Neurooncología 56
Early research (Phase 1)Looking for participantsNCT06860594
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Adult Diffuse Midline Glioma, H3 K27-Mutant+4 more
National Cancer Institute (NCI) 30
Not applicableLooking for participantsNCT07832734
What this trial is testing

Metabolomics and Transcriptomics of Low- and High-Grade Gliomas

Who this might be right for
IDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565521
What this trial is testing

UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly

Who this might be right for
Glioblastoma Multiforme, AdultGlioblastoma, IDH-mutant
Sunnybrook Health Sciences Centre 55
Large-scale testing (Phase 3)Looking for participantsNCT07215910
What this trial is testing

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 3
Alliance for Clinical Trials in Oncology 408
Testing effectiveness (Phase 2)Looking for participantsNCT06047379
What this trial is testing

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Who this might be right for
Diffuse Astrocytoma, IDH-MutantGlioblastoma, IDH-wildtypeBrain Metastases, Adult+18 more
Neonc Technologies, Inc. 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Looking for participantsNCT05345002
What this trial is testing

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Who this might be right for
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCE 55
Testing effectiveness (Phase 2)Looking for participantsNCT07468136
What this trial is testing

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Who this might be right for
Anaplastic OligodendrogliomaAstrocytoma, IDH-Mutant, Grade 3Astrocytoma, IDH-Mutant, Grade 4+3 more
Mayo Clinic 33
Not applicableNot Yet RecruitingNCT06368934
What this trial is testing

Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma

Who this might be right for
GliomaGlioblastoma
Huashan Hospital 326
Early research (Phase 1)Active Not RecruitingNCT03528642
What this trial is testing

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Astrocytoma, IDH-Mutant, Grade 3
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07703436
What this trial is testing

Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease

Who this might be right for
Grade 2 IDH1-mutant GliomaGrade 3 IDH1-mutant GliomaGlioma+5 more
Nuvation Bio Inc. 40
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