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Results for “Atypical HUS”

47 trials

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Showing 20 of 47 results

Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Not applicableLooking for participantsNCT04745195
What this trial is testing

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium

Who this might be right for
Thrombotic MicroangiopathiesHemolytic Uremic Syndrome, AtypicalHemolytic-Uremic Syndrome
Maastricht University Medical Center 42
Not applicableAvailableNCT02355782
What this trial is testing

OMS721 Compassionate Use in Patients With Thrombotic Microangiopathy

Who this might be right for
Thrombotic Microangiopathy
Michal Nowicki
Testing effectiveness (Phase 2)Study completedNCT00844545
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 16
Early research (Phase 1)Study completedNCT06004947
What this trial is testing

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Who this might be right for
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Amgen 32
Not applicableActive Not RecruitingNCT06099236
What this trial is testing

A Prospective, Non-interventional, Observational Study of Presentation, Treatment Patterns and Outcomes in Atypical Hemolytic Uremic Syndrome Patients

Who this might be right for
Atypical Hemolytic Uremic Syndrome(aHUS)
AstraZeneca 367
Testing effectiveness (Phase 2)Study completedNCT02222545
What this trial is testing

Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies

Who this might be right for
Thrombotic Microangiopathies
Omeros Corporation 58
Not applicableLooking for participantsNCT07399730
What this trial is testing

Ravulizumab Outcomes in Polish Patients With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
AstraZeneca 80
Large-scale testing (Phase 3)Ended earlyNCT03205995
What this trial is testing

Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome

Who this might be right for
Thrombotic MicroangiopathiesAtypical Hemolytic Uremic Syndrome
Omeros Corporation 6
Not applicableStudy completedNCT01770951
What this trial is testing

A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 30
Not applicableEnded earlyNCT01522170
What this trial is testing

AHUS Observational Long Term Follow-Up

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 94
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Not applicableEnded earlyNCT02614898
What this trial is testing

Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 67
Testing effectiveness (Phase 2)Study completedNCT01757431
What this trial is testing

The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 2
Not applicableStudy completedNCT07218536
What this trial is testing

The Burden of Atypical Hemolytic Uremic Syndrome and The Clinical Characteristics of Patients in Egyptian Hospitals A Multicenter, Observational, Retrospective Cohort Study in Egypt

Who this might be right for
Atypical Hemolytic Uremic Syndrome
AstraZeneca 200
Large-scale testing (Phase 3)Looking for participantsNCT05935215
What this trial is testing

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05684159
What this trial is testing

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

Who this might be right for
aHUS - Atypical Hemolytic Uremic Syndrome
NovelMed Therapeutics 12
Not applicableUnknownNCT03605511
What this trial is testing

TTP and aHUS in Complicated Pregnancies

Who this might be right for
Thrombotic Thrombocytopenic PurpuraAtypical Hemolytic Uremic SyndromePre-Eclampsia+5 more
University College, London 150
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 65
Large-scale testing (Phase 3)Study completedNCT04859608
What this trial is testing

Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)

Who this might be right for
Hemolytic-Uremic Syndrome, Atypical
University Hospital, Tours 40
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