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Results for “Atypical Hemolytic Uremic”

47 trials

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Showing 20 of 47 results

Not applicableLooking for participantsNCT06312644
What this trial is testing

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Who this might be right for
Ultomiris-exposed Pregnant/ PostpartumPregnancyParoxysmal Nocturnal Hemoglobinuria (PNH)+3 more
Alexion Pharmaceuticals, Inc. 75
Testing effectiveness (Phase 2)Study completedNCT00844844
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 1
Large-scale testing (Phase 3)Study completedNCT05876351
What this trial is testing

Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China

Who this might be right for
Atypical Hemolytic Uremic
Alexion Pharmaceuticals, Inc. 25
Not applicableStudy completedNCT01755429
What this trial is testing

To Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS Patients

Who this might be right for
ATYPICAL HEMOLYTIC UREMIC SYNDROME (AHUS)
Alexion Pharmaceuticals, Inc. 2
Not applicableLooking for participantsNCT05996731
What this trial is testing

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Who this might be right for
Atypical Hemolytic Uremic SyndromeMembranoproliferative GlomerulonephritisAutosomal Dominant Polycystic Kidney+1 more
Mario Negri Institute for Pharmacological Research 105
Large-scale testing (Phase 3)Active Not RecruitingNCT04861259
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Hoffmann-La Roche 83
Not applicableLooking for participantsNCT01522183
What this trial is testing

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 3,000
Not applicableWithdrawnNCT02626663
What this trial is testing

The Role of Microparticles as a Biomarker

Who this might be right for
Atypical Hemolytic Uremic SyndromeThrombotic Thrombocytopenic PurpuraMicroparticles+1 more
University of Rochester
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Not applicableEnded earlyNCT02614898
What this trial is testing

Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 67
Not applicableEnded earlyNCT01522170
What this trial is testing

AHUS Observational Long Term Follow-Up

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 94
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Not applicableLooking for participantsNCT04745195
What this trial is testing

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium

Who this might be right for
Thrombotic MicroangiopathiesHemolytic Uremic Syndrome, AtypicalHemolytic-Uremic Syndrome
Maastricht University Medical Center 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05684159
What this trial is testing

Study of NM8074 in Patients with AHUS with Evidence of Ongoing Thrombotic Microangiopathy

Who this might be right for
AHUS - Atypical Hemolytic Uremic Syndrome
NovelMed Therapeutics 12
Not applicableUnknownNCT03574506
What this trial is testing

Eculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case Series

Who this might be right for
Atypical Hemolytic Uremic SyndromePregnancy
Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 50
Testing effectiveness (Phase 2)Study completedNCT01193348
What this trial is testing

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 22
Post-approval studies (Phase 4)Study completedNCT02574403
What this trial is testing

Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Nantes University Hospital 58
Testing effectiveness (Phase 2)Study completedNCT02222545
What this trial is testing

Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies

Who this might be right for
Thrombotic Microangiopathies
Omeros Corporation 58
Testing effectiveness (Phase 2)Study completedNCT01194973
What this trial is testing

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 44
Testing effectiveness (Phase 2)Study completedNCT00844428
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 5
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