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Results for “Autophagy”

122 trials

Showing 20 of 122 results

Testing effectiveness (Phase 2)Ended earlyNCT00765765
What this trial is testing

Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer

Who this might be right for
Breast Cancer
University of Medicine and Dentistry of New Jersey 6
Early research (Phase 1)Study completedNCT01023737
What this trial is testing

Hydroxychloroquine + Vorinostat in Advanced Solid Tumors

Who this might be right for
Malignant Solid Tumour
The University of Texas Health Science Center at San Antonio 72
Testing effectiveness (Phase 2)Study completedNCT01510119
What this trial is testing

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

Who this might be right for
Metastatic Clear Cell Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine 40
Not applicableEnded earlyNCT03946774
What this trial is testing

Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling

Who this might be right for
Dietary Protein
Washington University School of Medicine 21
Not applicableUnknownNCT05524376
What this trial is testing

Regulatory Network and Diagnostic Value of Key Autophagy-related Genes in Sepsis

Who this might be right for
SepsisAutophagy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 40
Not applicableUnknownNCT03922698
What this trial is testing

Potential Impact of Neuroimmune and Autophagic Alterations on the Progression and Severity of Human Atherosclerotic Process

Who this might be right for
Carotid Atherosclerosis
Neuromed IRCCS 50
Not applicableNot Yet RecruitingNCT06244849
What this trial is testing

TOward a Better Understanding of the autoPhagy Machinery for the Identification of Potential Novel Biomarkers and Therapeutic Targets in Crohn's Disease - TOPIC Study

Who this might be right for
Crohn's Disease
Hospices Civils de Lyon 170
Testing effectiveness (Phase 2)WithdrawnNCT02432417
What this trial is testing

The Addition of Chloroquine to Chemoradiation for Glioblastoma,

Who this might be right for
GlioblastomaAstrocytoma, Grade IV
Maastricht Radiation Oncology
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Not applicableStudy completedNCT06445569
What this trial is testing

Safety and Efficacy of KH-1 for Stimulating Autophagy in Non-diabetic Adults With Elevated Blood Glucose Concentration

Who this might be right for
PreDiabetesAging
Kalin Health, LLC 42
Testing effectiveness (Phase 2)Looking for participantsNCT04841148
What this trial is testing

Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

Who this might be right for
Breast Cancer
Abramson Cancer Center at Penn Medicine 96
Very early researchStudy completedNCT00962845
What this trial is testing

Hydroxychloroquine in Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery

Who this might be right for
Melanoma (Skin)
Rutgers, The State University of New Jersey 20
Not applicableStudy completedNCT03979651
What this trial is testing

MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma

Who this might be right for
Metastatic NRAS Melanoma
Hospices Civils de Lyon 29
Not applicableNot Yet RecruitingNCT05842564
What this trial is testing

Autophagy in Paediatric Crohn's Disease

Who this might be right for
Crohn DiseasePediatric Crohns Disease
Hospices Civils de Lyon 70
Large-scale testing (Phase 3)Looking for participantsNCT05986136
What this trial is testing

Activation of Autophagy and Suppression of Apoptosis by Dapagliflozin Attenuates Inflammatory Bowel Disease

Who this might be right for
Inflammatory Bowel Diseases
Mostafa Bahaa 50
Testing effectiveness (Phase 2)Ended earlyNCT00786682
What this trial is testing

Docetaxel and Hydroxychloroquine in Treating Patients With Metastatic Prostate Cancer

Who this might be right for
Prostate Cancer
University of Medicine and Dentistry of New Jersey 11
Not applicableStudy completedNCT04061070
What this trial is testing

Effects of Trehalose and Polyphenols in Vasculopathic Patients

Who this might be right for
Oxidative StressCardiovascular Diseases
University of Roma La Sapienza 80
Not applicableStudy completedNCT04200560
What this trial is testing

Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS

Who this might be right for
Vascular Diseases
University of Utah 16
Not applicableActive Not RecruitingNCT06115551
What this trial is testing

Fasting Mimicking Diet and Autophagy

Who this might be right for
DietAutophagy
L-Nutra Inc 30
Not applicableEnrolling By InvitationNCT07536659
What this trial is testing

Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals

Who this might be right for
Effects of Walking and Cycling on Serum Physiological Biomarkers Associated With Autophagy in Healthy Individuals
Kocaeli University 40
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