Not applicableActive Not RecruitingNCT06115551What this trial is testingFasting Mimicking Diet and AutophagyWho this might be right forDietAutophagy L-Nutra Inc 30
Not applicableUnknownNCT03922698What this trial is testingPotential Impact of Neuroimmune and Autophagic Alterations on the Progression and Severity of Human Atherosclerotic ProcessWho this might be right forCarotid Atherosclerosis Neuromed IRCCS 50
Not applicableLooking for participantsNCT05880095What this trial is testingHealthy Aging Through Time- Restricted Eating in Adults With Overweight/Obesity and Incipient Liver Disease: ENSATIWho this might be right forBiological Aging IMDEA Food 175
Testing effectiveness (Phase 2)Ended earlyNCT04214418What this trial is testingStudy of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced MalignanciesWho this might be right forGastrointestinal Cancer Columbia University 27
Very early researchStudy completedNCT00962845What this trial is testingHydroxychloroquine in Patients With Stage III or Stage IV Melanoma That Can Be Removed by SurgeryWho this might be right forMelanoma (Skin) Rutgers, The State University of New Jersey 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03598595What this trial is testingGemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory OsteosarcomaWho this might be right forRecurrent OsteosarcomaRefractory Osteosarcoma M.D. Anderson Cancer Center 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT06186102What this trial is testingPolyamine Treatment in Elderly Patients With Coronary Artery DiseaseWho this might be right forIschemic Heart DiseaseMyocardial InfarctionCardiovascular Diseases+11 more University of Aarhus 180
Not applicableLooking for participantsNCT07383311What this trial is testingAutophagy-Enhancers to Reduce Sleep DisturbancesWho this might be right forMild Cognitive Impairment Due to Alzheimer's Disease University Medicine Greifswald 76
Not applicableStudy completedNCT03175874What this trial is testingAutophagy and Pathological AgingWho this might be right forOsteoporosis Centre Hospitalier Universitaire de Nice 82
Early research (Phase 1)Ended earlyNCT01144169What this trial is testingStudy of Hydroxychloroquine Before Surgery in Patients With Primary Renal Cell CarcinomaWho this might be right forRenal Cell Carcinoma University of Pittsburgh 7
Early research (Phase 1)UnknownNCT04663854What this trial is testingMycose AdminiStration for HealIng Alzheimer NEuropathy (MASHIANE)Who this might be right forAlzheimer Disease Mashhad University of Medical Sciences 20
Not applicableStudy completedNCT03326648What this trial is testingThe Role of Muscle Protein Breakdown in the Regulation of Muscle Quality in Frail Elderly IndividualsWho this might be right forSarcopenia Truls Raastad 34
Testing effectiveness (Phase 2)Study completedNCT01649947What this trial is testingModulation of Autophagy in Patients With Advanced/Recurrent Non-small Cell Lung Cancer - Phase IIWho this might be right forNon-small Cell Lung CancerAdvanced Non-small Cell Lung CancerRecurrent Non-small Cell Lung Cancer Rutgers, The State University of New Jersey 32
Large-scale testing (Phase 3)Study completedNCT03309007What this trial is testingA Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With PrediabetesWho this might be right forPreDiabetesAging University of New Mexico 25
Testing effectiveness (Phase 2)WithdrawnNCT02432417What this trial is testingThe Addition of Chloroquine to Chemoradiation for Glioblastoma,Who this might be right forGlioblastomaAstrocytoma, Grade IV Maastricht Radiation Oncology
Early research (Phase 1)Study completedNCT01023737What this trial is testingHydroxychloroquine + Vorinostat in Advanced Solid TumorsWho this might be right forMalignant Solid Tumour The University of Texas Health Science Center at San Antonio 72
Not applicableStudy completedNCT03979651What this trial is testingMEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) MelanomaWho this might be right forMetastatic NRAS Melanoma Hospices Civils de Lyon 29
Not applicableUnknownNCT04284306What this trial is testingImmunohistochemical Assessment of Programmed Death ligand1 and LC3B in GBMWho this might be right forGlioblastoma Multiforme Assiut University 61
Not applicableWithdrawnNCT04842864What this trial is testingTime Course for Fasting-induced Autophagy in HumansWho this might be right forFastingAutophagyAging Well+1 more Montefiore Medical Center
Not applicableStudy completedNCT04706000What this trial is testingAutophagy Markers in Endometrial PolypsWho this might be right forEndometrial PolypAutophagy Muğla Sıtkı Koçman University 30