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Results for “Avapritinib”

26 trials

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Showing 20 of 26 results

Post-approval studies (Phase 4)Study completedNCT04825574
What this trial is testing

Study for Patients Previously Treated in Avapritinib Clinical Trials

Who this might be right for
Gastrointestinal Stromal Tumors
Blueprint Medicines Corporation 2
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Not applicableUnknownNCT04927260
What this trial is testing

French Long Term Registry With Longitudinal Follow up of PDGFRA D842V-GIST Patients

Who this might be right for
GISTGIST, MalignantPDGFR-Alpha D842V
Centre Leon Berard 25
Not applicableLooking for participantsNCT05464875
What this trial is testing

Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors

Who this might be right for
Gastrointestinal Stromal TumorsUnresectable Solid TumorRecurrent Metastatic Malignant Neoplasm
Xinhua Zhang, MD 74
Post-approval studies (Phase 4)Looking for participantsNCT06748001
What this trial is testing

Avapritinib Rollover Study

Who this might be right for
Mastocytosis, Systemic
Blueprint Medicines Corporation 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03731260
What this trial is testing

(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 251
Testing effectiveness (Phase 2)UnknownNCT05821738
What this trial is testing

Avapritinib in CBF-AML With KIT Mutations

Who this might be right for
Core Binding Factor Acute Myeloid LeukemiaKIT Mutation-Related Tumors
The First Affiliated Hospital of Soochow University 50
Not applicableStudy completedNCT04695431
What this trial is testing

Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM

Who this might be right for
Advanced Systemic MastocytosisAggressive Systemic MastocytosisSystemic Mastocytosis With an Associated Hematological Neoplasm+1 more
Blueprint Medicines Corporation 317
Not applicableLooking for participantsNCT07255638
What this trial is testing

A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 80
Testing effectiveness (Phase 2)Looking for participantsNCT04116541
What this trial is testing

A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.

Who this might be right for
Malignant Solid Tumor
Centre Leon Berard 455
Not applicableLooking for participantsNCT05461664
What this trial is testing

Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA

Who this might be right for
Gastrointestinal Stromal TumorsUnresectable Solid TumorRecurrent Metastatic Malignant Neoplasm
Xinhua Zhang, MD 74
Early research (Phase 1)Study completedNCT02508532
What this trial is testing

(NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors

Who this might be right for
Gastrointestinal Stromal Tumors (GIST)Other Relapsed or Refractory Solid Tumors
Blueprint Medicines Corporation 250
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06765915
What this trial is testing

Avapritinib Maintenance for AML With KIT Mutations

Who this might be right for
AML, Adult
Ruijin Hospital 47
Not applicableStudy completedNCT05381753
What this trial is testing

Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World

Who this might be right for
Gastrointestinal Stromal Tumors
CStone Pharmaceuticals 61
Testing effectiveness (Phase 2)Study completedNCT04254939
What this trial is testing

CS3007 in Subjects With Gastrointestinal Stromal Tumor

Who this might be right for
Gastrointestinal Stromal Tumors
CStone Pharmaceuticals 65
Testing effectiveness (Phase 2)Looking for participantsNCT07028073
What this trial is testing

A New Treatment of Newly Diagnosed KIT Mutation CBF-Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With T(8;21)(Q22;Q22)Acute Myeloid Leukemia With T(16;16)(P13;Q22)KIT Gene Mutation+1 more
The First Affiliated Hospital of Soochow University 78
Testing effectiveness (Phase 2)Study completedNCT04773782
What this trial is testing

Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

Who this might be right for
Solid Tumor, Unspecified, ChildRelapsed Solid NeoplasmCNS Tumor
Blueprint Medicines Corporation 29
Testing effectiveness (Phase 2)Looking for participantsNCT06783790
What this trial is testing

Avapritinib Combined With Azacitidine and Venetoclax in the Treatment of Relapsed AML After Allo-HSCT

Who this might be right for
AML (Acute Myelogenous Leukemia)
Institute of Hematology & Blood Diseases Hospital, China 20
Early research (Phase 1)Looking for participantsNCT06327685
What this trial is testing

Avapritinib With Decitabine in Patients With SM-AHN

Who this might be right for
Systemic Mastocytosis With an Associated Hematologic Neoplasm
H. Lee Moffitt Cancer Center and Research Institute 34
Large-scale testing (Phase 3)Study completedNCT03465722
What this trial is testing

(VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST

Who this might be right for
GIST
Blueprint Medicines Corporation 476
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