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Results for “B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative”

80 trials

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Showing 20 of 80 results

Large-scale testing (Phase 3)Ended earlyNCT02013167
What this trial is testing

Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Amgen 405
Not applicableEnded earlyNCT00008216
What this trial is testing

Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Adult Langerhans Cell HistiocytosisChildhood Langerhans Cell HistiocytosisLeukemia+4 more
Columbia University 48
Early research (Phase 1)Study completedNCT00005092
What this trial is testing

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
M.D. Anderson Cancer Center 7
Large-scale testing (Phase 3)Active Not RecruitingNCT02883049
What this trial is testing

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, BCR-ABL1-LikeCentral Nervous System Leukemia+1 more
National Cancer Institute (NCI) 5,949
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07493408
What this trial is testing

Asciminib & Standard-of-Care Integration in Maintenance Therapy for POST Allogeneic Stem Cell Transplant (Allo-HSCT) of Patient With Ph+ B-ALL or Blastic Transformed CML

Who this might be right for
Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)Blastic Transformation of Chronic Myeloid LeukemiaPhiladelphia Chromosome-positive B-cell Acute Lymphoblastic Leukemia (Ph+ B-ALL)+1 more
The University of Hong Kong
Early research (Phase 1)Ended earlyNCT02819804
What this trial is testing

Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Lymphoblastic Leukemia+2 more
Northwestern University 1
Large-scale testing (Phase 3)Study completedNCT00265837
What this trial is testing

Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 72
Early research (Phase 1)Looking for participantsNCT04260022
What this trial is testing

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

Who this might be right for
Leukemia, Myeloid, ChronicMyeloid LeukemiaChronic Myeloid Leukemia+2 more
Ascentage Pharma Group Inc. 242
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Study completedNCT01256398
What this trial is testing

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Ended earlyNCT02420717
What this trial is testing

Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Ph-Like Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
M.D. Anderson Cancer Center 11
Testing effectiveness (Phase 2)Looking for participantsNCT07105579
What this trial is testing

Effectiveness and Safety of Blinatumomab and Donor Lymphocyte Infusion in Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation for High-risk Ph Negative B Cell Acute Lymphoblastic Leukemia

Who this might be right for
LeukemiaRelapse
First Affiliated Hospital of Zhejiang University 31
Testing effectiveness (Phase 2)Study completedNCT04788472
What this trial is testing

Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph+ B-ALL

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Not applicableNot Yet RecruitingNCT06649422
What this trial is testing

Reduced-Dose Chemo Followed by 14 Days of Blinatumomab for Newly Diagnosed Adult B-ALL Patients: a Multicenter Study

Who this might be right for
Leukemia, Lymphocytic, Acute, Adult
Shandong University 36
Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7
Large-scale testing (Phase 3)Looking for participantsNCT07152041
What this trial is testing

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)Childhood Leukemia, Acute Lymphoblastic
Institute of Hematology & Blood Diseases Hospital, China 150
Not applicableStudy completedNCT03118128
What this trial is testing

Metformin Reduce the Relapse Rate on Patients With B-cell Precursor (Ph+ Negative) Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Hospital General de Mexico 102
Early research (Phase 1)Looking for participantsNCT05157971
What this trial is testing

Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaPh-Like Acute Lymphoblastic Leukemia
City of Hope Medical Center 24
Testing effectiveness (Phase 2)UnknownNCT06078306
What this trial is testing

CD19CD22 CAR-T Therapy in Patients With High-Risk B Acute Lymphoblastic Leukemia (B-ALL).

Who this might be right for
B Acute Lymphoblastic LeukemiaPh-Negative ALLHigh Risk Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 20
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