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Results for “B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)Study completedNCT01256398
What this trial is testing

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07301424
What this trial is testing

Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)BCR-ABL Positive Acute Lymphoblastic Leukemia
University of Alberta 80
Early research (Phase 1)Looking for participantsNCT03595917
What this trial is testing

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Marlise Luskin, MD 40
Early research (Phase 1)Active Not RecruitingNCT04872790
What this trial is testing

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Mixed Phenotype Acute Leukemia+2 more
OHSU Knight Cancer Institute 20
Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7
Testing effectiveness (Phase 2)Looking for participantsNCT06738368
What this trial is testing

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeT Acute Lymphoblastic Leukemia
University of Washington 30
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Not applicableStudy completedNCT00003538
What this trial is testing

Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Large-scale testing (Phase 3)Looking for participantsNCT07441291
What this trial is testing

CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT

Who this might be right for
B ALLAllogenetic Hematopoietic Stem Cell TransplantationMRD-positive
Peking University People's Hospital 70
Testing effectiveness (Phase 2)Looking for participantsNCT06918431
What this trial is testing

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeLymphoblastic Lymphoma
City of Hope Medical Center 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Study completedNCT01769209
What this trial is testing

Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Adult Acute Lymphoblastic Leukemia (ALL)Ph-positive Adult Acute Lymphoblastic Leukemia (ALL)Recurrent Adult Acute Lymphoblastic Leukemia (ALL)+1 more
Stanford University 18
Not applicableLooking for participantsNCT06785324
What this trial is testing

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia Chromosome NegativeB Cell Acute Lymphoblastic Leukemia (B-ALL)B-ALL
University of Chicago 20
Testing effectiveness (Phase 2)Study completedNCT00787761
What this trial is testing

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Who this might be right for
Myeloproliferative DisordersKidney CancerLeukemia+4 more
Northside Hospital, Inc. 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07493408
What this trial is testing

Asciminib & Standard-of-Care Integration in Maintenance Therapy for POST Allogeneic Stem Cell Transplant (Allo-HSCT) of Patient With Ph+ B-ALL or Blastic Transformed CML

Who this might be right for
Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)Blastic Transformation of Chronic Myeloid LeukemiaPhiladelphia Chromosome-positive B-cell Acute Lymphoblastic Leukemia (Ph+ B-ALL)+1 more
The University of Hong Kong
Early research (Phase 1)Ended earlyNCT02819804
What this trial is testing

Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Lymphoblastic Leukemia+2 more
Northwestern University 1
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Not applicableNot Yet RecruitingNCT06649422
What this trial is testing

Reduced-Dose Chemo Followed by 14 Days of Blinatumomab for Newly Diagnosed Adult B-ALL Patients: a Multicenter Study

Who this might be right for
Leukemia, Lymphocytic, Acute, Adult
Shandong University 36
Testing effectiveness (Phase 2)Ended earlyNCT03518112
What this trial is testing

Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
M.D. Anderson Cancer Center 6
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