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Results for “B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative”

78 trials

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Showing 20 of 78 results

Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Cancer Center at Thomas Jefferson University 7
Testing effectiveness (Phase 2)Study completedNCT00787761
What this trial is testing

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Who this might be right for
Myeloproliferative DisordersKidney CancerLeukemia+4 more
Northside Hospital, Inc. 24
Large-scale testing (Phase 3)UnknownNCT04375683
What this trial is testing

Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

Who this might be right for
Acute Lymphocytic Leukemia, Adult B-CellBCR-ABL1 Fusion Protein Expression
Zhongda Hospital 28
Testing effectiveness (Phase 2)Study completedNCT04788472
What this trial is testing

Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph+ B-ALL

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 28
Testing effectiveness (Phase 2)Temporarily pausedNCT03739814
What this trial is testing

Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Large-scale testing (Phase 3)Looking for participantsNCT04994717
What this trial is testing

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Amgen 304
Not applicableLooking for participantsNCT06481241
What this trial is testing

Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL

Who this might be right for
Philadelphia Chromosome Negative ALLAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 77
Large-scale testing (Phase 3)UnknownNCT03564470
What this trial is testing

Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL

Who this might be right for
LeukemiaLeukemia, AcuteLeukemia, Lymphoblastic+1 more
Nanfang Hospital, Southern Medical University 120
Not applicableLooking for participantsNCT06785324
What this trial is testing

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia Chromosome NegativeB Cell Acute Lymphoblastic Leukemia (B-ALL)B-ALL
University of Chicago 20
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Study completedNCT00458848
What this trial is testing

Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 470
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07301424
What this trial is testing

Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)BCR-ABL Positive Acute Lymphoblastic Leukemia
University of Alberta 80
Testing effectiveness (Phase 2)UnknownNCT03249870
What this trial is testing

Study of Inotuzumab Ozogamicin Combined to Chemotherapy in Older Patients With Philadelphia Chromosome-negative CD22+ B-cell Precursor ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) - Philadelphia Chromosome (Ph)-Negative CD22+ B-cell Precursor (BCP)
Versailles Hospital 130
Not applicableLooking for participantsNCT06481228
What this trial is testing

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Who this might be right for
Philadelphia Positive Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 82
Early research (Phase 1)Looking for participantsNCT04872790
What this trial is testing

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Mixed Phenotype Acute Leukemia+2 more
OHSU Knight Cancer Institute 20
Early research (Phase 1)Ended earlyNCT03579888
What this trial is testing

CD19-Specific T Cells Post AlloSCT

Who this might be right for
B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A RearrangedRecurrent B Acute Lymphoblastic LeukemiaRecurrent Chronic Lymphocytic Leukemia+14 more
M.D. Anderson Cancer Center 4
Early research (Phase 1)Looking for participantsNCT03595917
What this trial is testing

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Marlise Luskin, MD 40
Testing effectiveness (Phase 2)Looking for participantsNCT06393985
What this trial is testing

Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 30
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