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Results for “BRAF”

546 trials

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Showing 20 of 546 results

Large-scale testing (Phase 3)Study completedNCT03206151
What this trial is testing

CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Mabtech Pharmaceutical Co.,Ltd 520
Early research (Phase 1)Ended earlyNCT01611675
What this trial is testing

Leflunomide+Vemurafenib in V600 Mutant Met. Melanoma

Who this might be right for
Melanoma
Massachusetts General Hospital 3
Not applicableStudy completedNCT04961619
What this trial is testing

Adjuvant Dabrafenib and Trametinib Treatment in Patients With Completely Resected High-risk Stage III Melanoma.

Who this might be right for
Melanoma
Novartis Pharmaceuticals 39
Early research (Phase 1)Study completedNCT02608034
What this trial is testing

Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

Who this might be right for
Metastatic Melanoma, BRAF V600 Mutation Positive
Genentech, Inc. 32
Early research (Phase 1)Study completedNCT01877811
What this trial is testing

Study of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 143
Testing effectiveness (Phase 2)UnknownNCT04248387
What this trial is testing

Toripalimab in the Neoadjuvant Treatment of BRAF V600 Wild Type Melanoma

Who this might be right for
Melanoma Stage IIIB-IV
Fudan University 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439279
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Ended earlyNCT01616199
What this trial is testing

Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma

Who this might be right for
Advanced BRAF-mutant Cancers
Cascadian Therapeutics Inc. 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT02231775
What this trial is testing

Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation

Who this might be right for
Stage IIIB Cutaneous Melanoma AJCC v7Stage IIIC Cutaneous Melanoma AJCC v7
M.D. Anderson Cancer Center 58
Testing effectiveness (Phase 2)Study completedNCT01876212
What this trial is testing

Dendritic Cell Vaccines + Dasatinib for Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Walter J. Storkus 15
Early research (Phase 1)Study completedNCT02729298
What this trial is testing

First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsEGFR Positive Non-small Cell Lung CancerColorectal Carcinoma+2 more
Sumitomo Pharma America, Inc. 177
Testing effectiveness (Phase 2)Study completedNCT01336634
What this trial is testing

Study of Selective BRAF Kinase Inhibitor Dabrafenib Monotherapy Twice Daily and in Combination With Dabrafenib Twice Daily and Trametinib Once Daily in Combination Therapy in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer.

Who this might be right for
Cancer
Novartis Pharmaceuticals 177
Testing effectiveness (Phase 2)Ended earlyNCT02052193
What this trial is testing

Evaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb Study

Who this might be right for
Metastatic Melanoma (Carrying BRAF V600 Mutation)
University Hospital Tuebingen 8
Not applicableStudy completedNCT05984615
What this trial is testing

Real-world Evaluation of the Impact of Baseline Metastases on Clinical Outcomes Among BRAF Positive Metastatic Melanoma Patients

Who this might be right for
BRAF Positive Metastatic Melanoma
Novartis Pharmaceuticals 1,961
Testing effectiveness (Phase 2)Active Not RecruitingNCT04417621
What this trial is testing

Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma
Novartis Pharmaceuticals 134
Testing effectiveness (Phase 2)Looking for participantsNCT06079333
What this trial is testing

NEO- and Adjuvant Targeted Therapy in Braf-mutated Anaplastic Cancer of the Thyroid (NEO-ATACT Study)

Who this might be right for
Anaplastic Thyroid Cancer
Leiden University Medical Center 20
Early research (Phase 1)Not Yet RecruitingNCT07463365
What this trial is testing

Phase 1 Study of LUT017 Gel to Evaluate Safety and Wound Healing in Adults With Venous Leg Ulcers and Chronic Non-Healing Skin Wounds

Who this might be right for
Venous Leg UlcerChronic Non-Healing Cutaneous WoundsVLU
Antoni Ribas 18
Very early researchActive Not RecruitingNCT06011772
What this trial is testing

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

Who this might be right for
Colo-rectal Cancer
Roswell Park Cancer Institute 2
Not applicableStudy completedNCT02827565
What this trial is testing

Technical Optimization of Detection of KRAS, BRAF and NRAS Mutations on Tumor DNA Circulating in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Institut de Cancérologie de Lorraine 30
Early research (Phase 1)Study completedNCT03864042
What this trial is testing

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Melanoma
Pfizer 56
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