Early research (Phase 1)Ended earlyNCT01611675What this trial is testingLeflunomide+Vemurafenib in V600 Mutant Met. MelanomaWho this might be right forMelanoma Massachusetts General Hospital 3
Not applicableStudy completedNCT04961619What this trial is testingAdjuvant Dabrafenib and Trametinib Treatment in Patients With Completely Resected High-risk Stage III Melanoma.Who this might be right forMelanoma Novartis Pharmaceuticals 39
Early research (Phase 1)Study completedNCT02608034What this trial is testingInvestigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady StateWho this might be right forMetastatic Melanoma, BRAF V600 Mutation Positive Genentech, Inc. 32
Early research (Phase 1)Study completedNCT01877811What this trial is testingStudy of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid TumorsWho this might be right forSolid Tumors Hoffmann-La Roche 143
Testing effectiveness (Phase 2)Active Not RecruitingNCT02231775What this trial is testingDabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 MutationWho this might be right forStage IIIB Cutaneous Melanoma AJCC v7Stage IIIC Cutaneous Melanoma AJCC v7 M.D. Anderson Cancer Center 58
Testing effectiveness (Phase 2)Study completedNCT01336634What this trial is testingStudy of Selective BRAF Kinase Inhibitor Dabrafenib Monotherapy Twice Daily and in Combination With Dabrafenib Twice Daily and Trametinib Once Daily in Combination Therapy in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer.Who this might be right forCancer Novartis Pharmaceuticals 177
Testing effectiveness (Phase 2)Ended earlyNCT02052193What this trial is testingEvaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb StudyWho this might be right forMetastatic Melanoma (Carrying BRAF V600 Mutation) University Hospital Tuebingen 8
Not applicableStudy completedNCT02827565What this trial is testingTechnical Optimization of Detection of KRAS, BRAF and NRAS Mutations on Tumor DNA Circulating in Metastatic Colorectal CancerWho this might be right forMetastatic Colorectal Cancer Institut de Cancérologie de Lorraine 30
Testing effectiveness (Phase 2)Temporarily pausedNCT05756556What this trial is testingT3011 in Combination With Cobimetinib in Patients With Advanced MelanomaWho this might be right forMelanomaMalignant Melanoma ImmVira Pharma Co. Ltd 68
Early research (Phase 1)Ended earlyNCT01940809What this trial is testingIpilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by SurgeryWho this might be right forBRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more National Cancer Institute (NCI) 15
Large-scale testing (Phase 3)Active Not RecruitingNCT05270044What this trial is testingAdjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation.Who this might be right forMelanoma Pierre Fabre Medicament 815
Testing effectiveness (Phase 2)UnknownNCT05641493What this trial is testingA Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E MutationWho this might be right forNon Small Cell Lung Cancer Shanghai Henlius Biotech 49
Not applicableEnded earlyNCT01280643What this trial is testingCombination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal CancerWho this might be right forMetastatic Colorectal Cancer Fox Chase Cancer Center 3
Testing effectiveness (Phase 2)UnknownNCT05528406What this trial is testingA Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 MutationWho this might be right forSolid Tumor Shanghai Henlius Biotech 30
Testing effectiveness (Phase 2)Study completedNCT02631447What this trial is testingSequential Combo Immuno and Target Therapy (SECOMBIT) StudyWho this might be right forMetastatic Melanoma Fondazione Melanoma Onlus 251
Testing effectiveness (Phase 2)Active Not RecruitingNCT04238624What this trial is testingStudy of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid CancerWho this might be right forAnaplastic Thyroid CancerThyroid CancerBRAF Gene Mutation+1 more Memorial Sloan Kettering Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT01677741What this trial is testingDetermine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent SubjectsWho this might be right forNeoplasms, Brain Novartis Pharmaceuticals 85
Early research (Phase 1)Temporarily pausedNCT01841463What this trial is testingStudy of an Oral Cdk Inhibitor Administered With an Oral BRAF Inhibitor in Patients With Advanced or Inoperable Malignant Melanoma With BRAF MutationWho this might be right forAdvanced or Inoperable Malignant Melanoma With BRAF Mutation Piramal Enterprises Limited 100
Testing effectiveness (Phase 2)Study completedNCT00936221What this trial is testingComparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma PatientsWho this might be right forMelanoma AstraZeneca 385
Testing effectiveness (Phase 2)Study completedNCT03915951What this trial is testingAn Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung CancerWho this might be right forNon-small Cell Lung Cancer Pfizer 98