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Results for “BRAF Mutant Colorectal Cancer”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Ended earlyNCT06194877
What this trial is testing

Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Who this might be right for
Colorectal CancerPancreatic Ductal CancerAdvanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
MapKure, LLC 13
Testing effectiveness (Phase 2)UnknownNCT04653480
What this trial is testing

Surufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC

Who this might be right for
Colorectal Cancer
Zhejiang University 61
Testing effectiveness (Phase 2)Study completedNCT02380443
What this trial is testing

AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Mirror Biologics, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT01719380
What this trial is testing

Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Pfizer 156
Large-scale testing (Phase 3)Looking for participantsNCT06008119
What this trial is testing

Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Shanghai Kechow Pharma, Inc. 165
Early research (Phase 1)Study completedNCT01740648
What this trial is testing

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Who this might be right for
Recurrent Rectal CancerStage IIA Rectal CancerStage IIB Rectal Cancer+4 more
Ohio State University Comprehensive Cancer Center 19
Testing effectiveness (Phase 2)Looking for participantsNCT07790510
What this trial is testing

HSK42360-Na Tablets Combined With Cetuximab With or Without Chemotherapy in BRAF V600-Mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Haisco Pharmaceutical Group Co., Ltd. 180
Early research (Phase 1)Study completedNCT03415126
What this trial is testing

ASN007 in Patients With Advanced Solid Tumors

Who this might be right for
CancerMalignancyNeoplasia+16 more
Asana BioSciences 49
Early research (Phase 1)Study completedNCT01351103
What this trial is testing

LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Who this might be right for
Pancreatic CancerBRAF Mutant Colorectal CancerMelanoma+5 more
Novartis Pharmaceuticals 185
Testing effectiveness (Phase 2)Active Not RecruitingNCT05217446
What this trial is testing

Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Pfizer 108
Testing effectiveness (Phase 2)Study completedNCT02164916
What this trial is testing

S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network 106
Large-scale testing (Phase 3)Looking for participantsNCT07549399
What this trial is testing

SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 204
Testing effectiveness (Phase 2)Study completedNCT06908031
What this trial is testing

SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 49
Testing effectiveness (Phase 2)Study completedNCT04790448
What this trial is testing

Efficacy of VIC Regimen in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Sun Yat-sen University 37
Testing effectiveness (Phase 2)Looking for participantsNCT07789210
What this trial is testing

A Single-Arm, Phase II, Multicenter Clinical Study of Neoadjuvant Encorafenib Plus Cetuximab N01 and mFOLFOX6 in Patients With Locally Advanced BRAF V600E-Mutant Colorectal Cancer With or Without Resectable Metastases

Who this might be right for
Colorectal CancerBRAF V600E Mutation PositiveEncorafenib+1 more
Zhejiang University 25
Testing effectiveness (Phase 2)Study completedNCT05004350
What this trial is testing

A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.

Who this might be right for
BRAF V600EMetastatic Colorectal Cancer
Pierre Fabre Medicament 107
Large-scale testing (Phase 3)Active Not RecruitingNCT04607421
What this trial is testing

Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Who this might be right for
Neoplasms
Pfizer 841
Testing effectiveness (Phase 2)Study completedNCT02278133
What this trial is testing

Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations

Who this might be right for
Metastatic Colorectal Cancer
Array BioPharma 20
Testing effectiveness (Phase 2)Looking for participantsNCT07809893
What this trial is testing

Ivosidenib Plus mFOLFOXIRI and Celecoxib for BRAF-targeted Therapy-refractory BRAF V600E-mutant Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 45
Testing effectiveness (Phase 2)Looking for participantsNCT07150247
What this trial is testing

Safety and Efficacy of IB-FOLFIRI in BRAF V600E-Mutant Metastatic Colorectal Cancer

Who this might be right for
BRAF V600 Colorectal Cancer
Sun Yat-sen University 20
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