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Results for “BRAF Mutant Colorectal Cancer”

25 trials

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Showing 20 of 25 results

Early research (Phase 1)Ended earlyNCT06194877
What this trial is testing

Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Who this might be right for
Colorectal CancerPancreatic Ductal CancerAdvanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
MapKure, LLC 13
Large-scale testing (Phase 3)Study completedNCT02928224
What this trial is testing

Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Pfizer 702
Not applicableLooking for participantsNCT06749015
What this trial is testing

A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal CancerBRAF V600 Mutation
Fudan University 100
Not applicableNot Yet RecruitingNCT07007689
What this trial is testing

A Multi-omics Study of BRAF V600E Mutant Colorectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Sun Yat-sen University 200
Early research (Phase 1)Study completedNCT01436656
What this trial is testing

A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant Melanoma

Who this might be right for
Melanoma and Metastatic Colorectal Cancer
Pfizer 107
Testing effectiveness (Phase 2)Study completedNCT02380443
What this trial is testing

AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Mirror Biologics, Inc. 13
Large-scale testing (Phase 3)Looking for participantsNCT06008119
What this trial is testing

Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Shanghai Kechow Pharma, Inc. 165
Testing effectiveness (Phase 2)UnknownNCT04653480
What this trial is testing

Surufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC

Who this might be right for
Colorectal Cancer
Zhejiang University 61
Early research (Phase 1)Study completedNCT01351103
What this trial is testing

LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Who this might be right for
Pancreatic CancerBRAF Mutant Colorectal CancerMelanoma+5 more
Novartis Pharmaceuticals 185
Testing effectiveness (Phase 2)Study completedNCT03693170
What this trial is testing

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Pierre Fabre Medicament 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT05217446
What this trial is testing

Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Pfizer 107
Testing effectiveness (Phase 2)Study completedNCT02164916
What this trial is testing

S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network 106
Not applicableStudy completedNCT01437618
What this trial is testing

First-line FOLFOXIRI Plus Bevacizumab in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Azienda Ospedaliero, Universitaria Pisana 15
Early research (Phase 1)Study completedNCT03415126
What this trial is testing

ASN007 in Patients With Advanced Solid Tumors

Who this might be right for
CancerMalignancyNeoplasia+16 more
Asana BioSciences 49
Early research (Phase 1)Study completedNCT01740648
What this trial is testing

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Who this might be right for
Recurrent Rectal CancerStage IIA Rectal CancerStage IIB Rectal Cancer+4 more
Ohio State University Comprehensive Cancer Center 19
Testing effectiveness (Phase 2)Study completedNCT05004350
What this trial is testing

A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.

Who this might be right for
BRAF V600EMetastatic Colorectal Cancer
Pierre Fabre Medicament 107
Testing effectiveness (Phase 2)Looking for participantsNCT06908031
What this trial is testing

SCRT + mFOLFOX6 + PD-1 Antibody + Targeted Therapy for HIgh-Risk pMMR/MSS Rectal Cancer

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07178717
What this trial is testing

Characterize Encorafenib Plus Cetuximab as Rechallenge Treatment for BRAF V600E-mutant Metastatic Colorectal Cancer Patients After Previous Therapy With BRAF Inhibitors-based Combinations

Who this might be right for
Colo-rectal Cancer
Vall d'Hebron Institute of Oncology 25
Testing effectiveness (Phase 2)Study completedNCT02278133
What this trial is testing

Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations

Who this might be right for
Metastatic Colorectal Cancer
Array BioPharma 20
Large-scale testing (Phase 3)Active Not RecruitingNCT04607421
What this trial is testing

Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Who this might be right for
Neoplasms
Pfizer 831
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