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Results for “BRAF Mutant Melanoma”

68 trials

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Showing 20 of 68 results

Testing effectiveness (Phase 2)WithdrawnNCT03005639
What this trial is testing

ML29255 Neoadjuvant Vemurafenib and Cobimetinib Melanoma

Who this might be right for
Stage IIIB-C Melanoma
Inova Health Care Services
Early research (Phase 1)WithdrawnNCT04759846
What this trial is testing

Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma

Who this might be right for
BRAF V600 MutationUnresectable MelanomaMetastatic Melanoma+1 more
Pierre Fabre Medicament
Testing effectiveness (Phase 2)Ended earlyNCT01495988
What this trial is testing

Trial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant Melanoma

Who this might be right for
MelanomaMetastatic Melanoma
Melanoma Research Foundation Breakthrough Consortium 10
Large-scale testing (Phase 3)Study completedNCT01245062
What this trial is testing

GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive Melanoma

Who this might be right for
Melanoma
GlaxoSmithKline 322
Early research (Phase 1)Looking for participantsNCT04903119
What this trial is testing

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

Who this might be right for
Metastatic MelanomaBRAF Gene Mutation
Rina Plattner 30
Early research (Phase 1)Study completedNCT01351103
What this trial is testing

LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Who this might be right for
Pancreatic CancerBRAF Mutant Colorectal CancerMelanoma+5 more
Novartis Pharmaceuticals 185
Testing effectiveness (Phase 2)WithdrawnNCT02263898
What this trial is testing

Intermittent LGX818 and MEK162 in Treating Patients With Metastatic Melanoma Who Have BRAFV600 Mutations

Who this might be right for
Recurrent MelanomaStage IV Melanoma
Jonsson Comprehensive Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04417621
What this trial is testing

Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma
Novartis Pharmaceuticals 134
Early research (Phase 1)Study completedNCT03415126
What this trial is testing

ASN007 in Patients With Advanced Solid Tumors

Who this might be right for
CancerMalignancyNeoplasia+16 more
Asana BioSciences 49
Large-scale testing (Phase 3)Study completedNCT01667419
What this trial is testing

Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant Melanoma

Who this might be right for
Melanoma
Hoffmann-La Roche 498
Early research (Phase 1)Ended earlyNCT01940809
What this trial is testing

Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more
National Cancer Institute (NCI) 15
Early research (Phase 1)WithdrawnNCT02915666
What this trial is testing

A Clinical Trial of Patients With Melanoma

Who this might be right for
Melanoma
University of Texas Southwestern Medical Center
Not applicableStudy completedNCT04911998
What this trial is testing

A Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma Patients

Who this might be right for
Melanoma (Skin)Metastatic MelanomaBRAF V600 Mutation
Pierre Fabre Medicament 400
Testing effectiveness (Phase 2)Looking for participantsNCT06887088
What this trial is testing

Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases

Who this might be right for
Melanoma BRAF V600E/K MutatedMelanoma and Brain Metastases
Grupo Español Multidisciplinar de Melanoma 33
Testing effectiveness (Phase 2)Study completedNCT01072175
What this trial is testing

Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212

Who this might be right for
Cancer
Novartis Pharmaceuticals 430
Testing effectiveness (Phase 2)Ended earlyNCT03391050
What this trial is testing

APR-246 in Combination With Dabrafenib in Resistant Patients With BRAF V600 Mutant Melanoma

Who this might be right for
Melanoma
Aprea Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT01726738
What this trial is testing

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Who this might be right for
Stage III MelanomaStage IV MelanomaUnresectable Melanoma+1 more
UNC Lineberger Comprehensive Cancer Center 17
Early research (Phase 1)Ended earlyNCT03272464
What this trial is testing

INCB039110 in Combination With Dabrafenib and Trametinib in Patients With BRAF-mutant Melanoma and Other Solid Tumors.

Who this might be right for
Melanoma
Massachusetts General Hospital 1
Early research (Phase 1)Study completedNCT01436656
What this trial is testing

A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant Melanoma

Who this might be right for
Melanoma and Metastatic Colorectal Cancer
Pfizer 107
Testing effectiveness (Phase 2)UnknownNCT02036086
What this trial is testing

Study of Neo-adjuvant Use of Vemurafenib Plus Cobimetinib for BRAF Mutant Melanoma With Palpable Lymph Node Metastases

Who this might be right for
Melanoma
Sunnybrook Health Sciences Centre 24
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