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Results for “BRAF NP_004324.2:p.V600E”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT02034110
What this trial is testing

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Who this might be right for
Cancer
Novartis Pharmaceuticals 206
Testing effectiveness (Phase 2)Study completedNCT01336634
What this trial is testing

Study of Selective BRAF Kinase Inhibitor Dabrafenib Monotherapy Twice Daily and in Combination With Dabrafenib Twice Daily and Trametinib Once Daily in Combination Therapy in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer.

Who this might be right for
Cancer
Novartis Pharmaceuticals 177
Testing effectiveness (Phase 2)Active Not RecruitingNCT04061980
What this trial is testing

Encorafenib and Binimetinib With or Without Nivolumab in Treating Patients With Metastatic Radioiodine Refractory BRAF V600 Mutant Thyroid Cancer

Who this might be right for
BRAF NP_004324.2:p.V600MBRAF V600E Mutation PresentMetastatic Thyroid Gland Carcinoma+4 more
Providence Health & Services 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT06578559
What this trial is testing

Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 16
Testing effectiveness (Phase 2)Looking for participantsNCT06411600
What this trial is testing

Combination Therapy for BRAF-V600E Metastatic CRCm

Who this might be right for
Metastatic Colorectal Cancer
Vall d'Hebron Institute of Oncology 94
Testing effectiveness (Phase 2)Study completedNCT02392871
What this trial is testing

Radiotherapy & Combi in Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Melanoma and Skin Cancer Trials Limited 10
Testing effectiveness (Phase 2)Study completedNCT03693170
What this trial is testing

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Pierre Fabre Medicament 95
Testing effectiveness (Phase 2)Ended earlyNCT05576896
What this trial is testing

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

Who this might be right for
Stage IV Colorectal Cancer Positive for BRAF V600E MutationColorectal CancerColorectal Cancer Stage IV
Northwestern University 7
Testing effectiveness (Phase 2)UnknownNCT05528406
What this trial is testing

A Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 Mutation

Who this might be right for
Solid Tumor
Shanghai Henlius Biotech 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05710406
What this trial is testing

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Who this might be right for
Colon AdenocarcinomaMicrosatellite Stable Colon CarcinomaStage IIB Colon Cancer AJCC v8+2 more
Alliance for Clinical Trials in Oncology 1
Large-scale testing (Phase 3)Active Not RecruitingNCT04940052
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer

Who this might be right for
Differentiated Thyroid Cancer (DTC)
Novartis Pharmaceuticals 153
Testing effectiveness (Phase 2)UnknownNCT05092815
What this trial is testing

The Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E Mutation

Who this might be right for
Langerhans Cell HistiocytosisErdheim-Chester DiseaseLCH+1 more
Shanghai Henlius Biotech 25
Testing effectiveness (Phase 2)Ended earlyNCT02410863
What this trial is testing

Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanoma

Who this might be right for
Malignant Melanoma
Prof. Dr. med. Dirk Schadendorf 10
Testing effectiveness (Phase 2)Looking for participantsNCT07506109
What this trial is testing

A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer

Who this might be right for
BRAF V600EColorectal CancerSintilimab+4 more
Tianjin Medical University Cancer Institute and Hospital 49
Not applicableStudy completedNCT03363347
What this trial is testing

BRAF V600E and Redifferentiation Therapy in Radioiodine-refractory Papillary Thyroid Cancer

Who this might be right for
Thyroid Cancer
Heidelberg University 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT06784648
What this trial is testing

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma MetastaticMelanoma of SkinMelanoma BRAF V600E/K Mutated+7 more
BioInvent International AB 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT02196181
What this trial is testing

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

Who this might be right for
Stage III Cutaneous Melanoma AJCC v7Stage IV Cutaneous Melanoma AJCC v6 and v7Unresectable Melanoma
National Cancer Institute (NCI) 280
Early research (Phase 1)Study completedNCT01767454
What this trial is testing

Study of Dabrafenib +/- Trametinib in Combination With Ipilimumab for V600E/K Mutation Positive Metastatic or Unresectable Melanoma

Who this might be right for
Solid Tumours
GlaxoSmithKline 38
Early research (Phase 1)Study completedNCT01791309
What this trial is testing

Vemurafenib and Panitumumab Combination Therapy in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Memorial Sloan Kettering Cancer Center 16
Early research (Phase 1)UnknownNCT05019534
What this trial is testing

Tolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E-mutated /MSS Metastatic Colorectal CancerVemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal Antibody
West China Hospital 12
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