Early research (Phase 1)Ended earlyNCT01611675What this trial is testingLeflunomide+Vemurafenib in V600 Mutant Met. MelanomaWho this might be right forMelanoma Massachusetts General Hospital 3
Early research (Phase 1)Study completedNCT02608034What this trial is testingInvestigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady StateWho this might be right forMetastatic Melanoma, BRAF V600 Mutation Positive Genentech, Inc. 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT02231775What this trial is testingDabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 MutationWho this might be right forStage IIIB Cutaneous Melanoma AJCC v7Stage IIIC Cutaneous Melanoma AJCC v7 M.D. Anderson Cancer Center 58
Testing effectiveness (Phase 2)Ended earlyNCT02052193What this trial is testingEvaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb StudyWho this might be right forMetastatic Melanoma (Carrying BRAF V600 Mutation) University Hospital Tuebingen 8
Testing effectiveness (Phase 2)UnknownNCT05528406What this trial is testingA Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 MutationWho this might be right forSolid Tumor Shanghai Henlius Biotech 30
Testing effectiveness (Phase 2)Study completedNCT01677741What this trial is testingDetermine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent SubjectsWho this might be right forNeoplasms, Brain Novartis Pharmaceuticals 85
Testing effectiveness (Phase 2)Study completedNCT03915951What this trial is testingAn Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung CancerWho this might be right forNon-small Cell Lung Cancer Pfizer 98
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05275374What this trial is testingXP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 MutationWho this might be right forCancerBRAF V600 MutationMelanoma+3 more Xynomic Pharmaceuticals, Inc. 221
Not applicableLooking for participantsNCT06749015What this trial is testingA Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)Who this might be right forMetastatic Colorectal CancerBRAF V600 Mutation Fudan University 100
Testing effectiveness (Phase 2)Study completedNCT02296112What this trial is testingTrametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 MutationsWho this might be right forRecurrent MelanomaStage IIIB MelanomaStage IIIC Melanoma+1 more Vanderbilt-Ingram Cancer Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT07110246What this trial is testingDabrafenib and Trametinib for BRAF V600 Mutant Low-Grade GliomasWho this might be right forBRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more University of California, San Francisco 96
Testing effectiveness (Phase 2)UnknownNCT05102292What this trial is testingThe Efficacy and Safety of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With BRAF V600 MutationWho this might be right forAnaplastic Thyroid CancerATC Shanghai Henlius Biotech 25
Testing effectiveness (Phase 2)Study completedNCT02083354What this trial is testingStudy to Investigate the Objective Response Rate of Dabrafenib in Combination With Trametinib in Subjects With BRAF V600 Mutation-Positive MelanomaWho this might be right forCancerMelanoma Novartis Pharmaceuticals 77
Early research (Phase 1)Study completedNCT01436656What this trial is testingA Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant MelanomaWho this might be right forMelanoma and Metastatic Colorectal Cancer Pfizer 107
Early research (Phase 1)Ended earlyNCT04190628What this trial is testingSafety and Tolerability of ABM-1310 in Patients With Advanced Solid TumorsWho this might be right forAdvanced Solid TumorBRAF V600 Mutation ABM Therapeutics Corporation 53
Not applicableStudy completedNCT01804140What this trial is testingA Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies of Zelboraf (Vemurafenib)Who this might be right forMultiple Myeloma, Neoplasms Genentech, Inc. 662
Not applicableStudy completedNCT03139513What this trial is testingAdult Participants With BRAF V600 Mutation-Positive Advanced Melanoma Treated With Cobimetinib (Cotellic®) During the French Early Access Program (Temporary Authorization for Use [TAU])Who this might be right forMelanoma Hoffmann-La Roche 200
Early research (Phase 1)Study completedNCT04462471What this trial is testingVemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid CancersWho this might be right forThyroid CarcinomaThyroid CancerThyroid Cancer, Follicular+3 more Memorial Sloan Kettering Cancer Center 8
Early research (Phase 1)Ended earlyNCT05501912What this trial is testingABM-1310 in Patients With BRAF V600-Mutant Advanced Solid TumorsWho this might be right forAdvanced Solid TumorBRAF V600 Mutation ABM Therapeutics Shanghai Company Limited 20
Not applicableNo Longer AvailableNCT04544202What this trial is testingCompassionate Use Program BRAF Mutation-positive Patients in the Adjuvant Treatment of Melanoma After Surgical ResectionWho this might be right forMelanomaAdjuvant Novartis Pharmaceuticals