Not applicableStudy completedNCT03416933What this trial is testingTherapeutic Drug Monitoring of BRAF-mutated Advanced MelanomaWho this might be right forMelanoma (Skin) Institut de Cancérologie de Lorraine 35
Not applicableStudy completedNCT03663647What this trial is testingAdvanced Melanoma in Russian ExperienceWho this might be right forCutaneous Melanoma, Stage IVBRAF V600 Mutation MelanomaPRO, Russia 382
Testing effectiveness (Phase 2)Study completedNCT03220035What this trial is testingVemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)Who this might be right forAdvanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT03235245What this trial is testingImmunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and BinimetinibWho this might be right forUnresectable Stage III MelanomaStage IV Melanoma European Organisation for Research and Treatment of Cancer - EORTC 271
Early research (Phase 1)Study completedNCT02082665What this trial is testingEffects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and MidazolamWho this might be right forCancer GlaxoSmithKline 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT04324112What this trial is testingEncorafenib Plus Binimetinib for People With BRAF V600 Mutated Relapsed/Refractory HCLWho this might be right forHairy Cell Leukemia National Cancer Institute (NCI) 28
Early research (Phase 1)Looking for participantsNCT07561554What this trial is testingPhase I Study of HSK42360-Na in Solid Tumors With BRAF V600 MutationWho this might be right forSolid Tumors (Phase 1) Haisco Pharmaceutical Group Co., Ltd. 159
Post-approval studies (Phase 4)Study completedNCT01739764What this trial is testingAn Extension (Rollover) Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Malignancies Previously Enrolled in an Antecedent Vemurafenib ProtocolWho this might be right forNeoplasms Hoffmann-La Roche 215
Testing effectiveness (Phase 2)Study completedNCT02296112What this trial is testingTrametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 MutationsWho this might be right forRecurrent MelanomaStage IIIB MelanomaStage IIIC Melanoma+1 more Vanderbilt-Ingram Cancer Center 9
Not applicableStudy completedNCT04911998What this trial is testingA Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma PatientsWho this might be right forMelanoma (Skin)Metastatic MelanomaBRAF V600 Mutation Pierre Fabre Medicament 400
Testing effectiveness (Phase 2)Ended earlyNCT04488003What this trial is testingStudy of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF AlterationsWho this might be right forAdvanced Solid TumorBRAF Gene MutationBRAF Gene Alteration+6 more BioMed Valley Discoveries, Inc 104
Testing effectiveness (Phase 2)Study completedNCT02836548What this trial is testingHDAC Inhibitor Vorinostat in Resistant BRAF V600 Mutated Advanced MelanomaWho this might be right forMelanomaSkin Neoplasms The Netherlands Cancer Institute 33
Early research (Phase 1)Temporarily pausedNCT04418167What this trial is testingJSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway MutationsWho this might be right forSolid Tumors JS InnoPharm, LLC 71
Testing effectiveness (Phase 2)Study completedNCT02768207What this trial is testingDetect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced MelanomaWho this might be right forMetastatic Melanoma Hoffmann-La Roche 40
Testing effectiveness (Phase 2)WithdrawnNCT03794297What this trial is testingDabrafenib and Trametinib in Treating Patients With Erdheim Chester Disease With BRAF V600 MutationsWho this might be right forErdheim-Chester Disease National Cancer Institute (NCI)
Early research (Phase 1)UnknownNCT03781219What this trial is testingA PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 MutationWho this might be right forSolid Tumor Shanghai Kechow Pharma, Inc. 45
Not applicableStudy completedNCT05806268What this trial is testingPatient Characteristics, Associated Factors, and Clinical Outcomes of Prescribing Encorafenib and Binimetenib Versus Dabrafenib and Trametinib Among BRAF v600 Mutated Metastatic Melanoma PatientsWho this might be right forBRAF v600 Mutated Metastatic Melanoma Novartis Pharmaceuticals 214
Early research (Phase 1)Study completedNCT04462471What this trial is testingVemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid CancersWho this might be right forThyroid CarcinomaThyroid CancerThyroid Cancer, Follicular+3 more Memorial Sloan Kettering Cancer Center 8
Early research (Phase 1)Study completedNCT01436656What this trial is testingA Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant MelanomaWho this might be right forMelanoma and Metastatic Colorectal Cancer Pfizer 107
Testing effectiveness (Phase 2)UnknownNCT05528406What this trial is testingA Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 MutationWho this might be right forSolid Tumor Shanghai Henlius Biotech 30