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Results for “BRAF V600E”

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Showing 20 of 0 results

Early research (Phase 1)UnknownNCT04965220
What this trial is testing

HLX208 (BRAF V600E Inhibitor) in Combination With Trametinib in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Shanghai Henlius Biotech 220
Testing effectiveness (Phase 2)Ended earlyNCT01586195
What this trial is testing

Study Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600E

Who this might be right for
Malignant Melanoma
Genentech, Inc. 31
Early research (Phase 1)Study completedNCT04462471
What this trial is testing

Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

Who this might be right for
Thyroid CarcinomaThyroid CancerThyroid Cancer, Follicular+3 more
Memorial Sloan Kettering Cancer Center 8
Testing effectiveness (Phase 2)UnknownNCT03727763
What this trial is testing

Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT)

Who this might be right for
Colorectal Cancer
Shanghai Changzheng Hospital 30
Very early researchUnknownNCT01417442
What this trial is testing

BRAF V600E Mutations In Papillary Thyroid Carcinoma

Who this might be right for
Papillary Thyroid Carcinoma
Bezmialem Vakif University 150
Testing effectiveness (Phase 2)UnknownNCT05528406
What this trial is testing

A Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 Mutation

Who this might be right for
Solid Tumor
Shanghai Henlius Biotech 30
Testing effectiveness (Phase 2)Ended earlyNCT04585815
What this trial is testing

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Pfizer 34
Testing effectiveness (Phase 2)Ended earlyNCT04527549
What this trial is testing

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+2 more
ECOG-ACRIN Cancer Research Group 5
Early research (Phase 1)Ended earlyNCT03878719
What this trial is testing

Study of the Combination of Binimetinib and Encorafenib in Adolescent Patients With Unresectable or Metastatic BRAF V600-mutant Melanoma

Who this might be right for
Melanoma
Pfizer 1
Testing effectiveness (Phase 2)UnknownNCT05127759
What this trial is testing

The Efficacy and Safety of HLX208 in Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation

Who this might be right for
Metastatic Colorectal CancermCRC
Shanghai Henlius Biotech 25
Not applicableLooking for participantsNCT05868629
What this trial is testing

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

Who this might be right for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Looking for participantsNCT06207656
What this trial is testing

Study to Evaluate the Efficacy and Safety of Cetuximab in Combination with Encorafenib Plus Binimetinib As Induction Treatment in BRAF V600E Mutated MSS Initially Resectable or Potentially Resectable Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 70
Testing effectiveness (Phase 2)UnknownNCT03543306
What this trial is testing

Dabrafenib and Trametinib in Patients With Non-small Cell Lung Cancer Harboring V600E BRAF Mutation

Who this might be right for
CancerLung Cancer MetastaticBRAF V600E
Asan Medical Center 27
Testing effectiveness (Phase 2)UnknownNCT05641493
What this trial is testing

A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E Mutation

Who this might be right for
Non Small Cell Lung Cancer
Shanghai Henlius Biotech 49
Large-scale testing (Phase 3)Active Not RecruitingNCT05710406
What this trial is testing

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Who this might be right for
Colon AdenocarcinomaMicrosatellite Stable Colon CarcinomaStage IIB Colon Cancer AJCC v8+2 more
Alliance for Clinical Trials in Oncology 1
Testing effectiveness (Phase 2)UnknownNCT04984369
What this trial is testing

The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment

Who this might be right for
CRC
Shanghai Henlius Biotech 50
Testing effectiveness (Phase 2)UnknownNCT05092802
What this trial is testing

The Efficacy of HLX208 (BRAF V600E Inhibitor) for Refractory Primary Brain Tumors With BRAF Mutation After First-line Treatment

Who this might be right for
Brain Tumor, Primary
Shanghai Henlius Biotech 40
Testing effectiveness (Phase 2)WithdrawnNCT02143050
What this trial is testing

Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients

Who this might be right for
Melanoma
University of Louisville
Large-scale testing (Phase 3)Not Yet RecruitingNCT07004075
What this trial is testing

FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration

Who this might be right for
Low-grade GliomaPediatric Low-grade GliomaspLGG With BRAF Alteration
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 102
Large-scale testing (Phase 3)Not Yet RecruitingNCT06819605
What this trial is testing

Neoadjuvant Therapy With Conservative Surgery vs. Up-front Conservative Surgery for BRAF V600E-Mutated Ameloblastoma

Who this might be right for
Ameloblastoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 46
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