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Results for “BRCA Mutated”

177 trials

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Showing 20 of 177 results

Not applicableEnrolling By InvitationNCT06470685
What this trial is testing

Prophylactic Prostatectomy for Prostate Cancer (PPPC)

Who this might be right for
Prostate CancerGenetic Predisposition to DiseaseBRCA Mutation
Royal Marsden NHS Foundation Trust 20
Large-scale testing (Phase 3)Study completedNCT02184195
What this trial is testing

Olaparib in gBRCA Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy

Who this might be right for
Germline BRCA1/2 Mutations andMetastatic Adenocarcinoma of the Pancreas
AstraZeneca 154
Testing effectiveness (Phase 2)WithdrawnNCT01661868
What this trial is testing

Olaparib for Patients With Recurrent BRCA Deficient Ovarian Cancer

Who this might be right for
Ovarian CancerPeritoneal CancerFallopian Tube Cancer
Dana-Farber Cancer Institute
Not applicableLooking for participantsNCT03667417
What this trial is testing

Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation

Who this might be right for
Breast CancersOvarian Cancers
Institut Paoli-Calmettes 5,000
Not applicableLooking for participantsNCT06588322
What this trial is testing

Detection of Homologous Recombination Pathway Gene Mutations in Circulating Tumour DNA From BRCA-mutated Ovarian Cancer Patients Receiving First-line PARP Inhibitor Maintenance Therapy

Who this might be right for
Ovarian Cancer
Institut Claudius Regaud 130
Not applicableStudy completedNCT00956384
What this trial is testing

One-stage Breast Reconstruction Using Dermal Matrix/Implant Versus Two-stage Expander/Implant Procedure

Who this might be right for
Breast Cancer
University Health Network, Toronto 198
Early research (Phase 1)Looking for participantsNCT06177171
What this trial is testing

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

Who this might be right for
BRCA1 MutationBRCA2 MutationBRCA Mutation+3 more
Pamela Munster 18
Not applicableStudy completedNCT03590938
What this trial is testing

Lynparza Breast Cancer Clinical Experience Investigation

Who this might be right for
Breast Cancer
AstraZeneca 111
Not applicableActive Not RecruitingNCT06733337
What this trial is testing

Learn About the Safety of TALZENNA in People With Prostate Cancer.

Who this might be right for
Prostate Cancer
Pfizer 1
Testing effectiveness (Phase 2)Looking for participantsNCT05485766
What this trial is testing

Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast NeoplasmsTriple Negative Breast CancerBreast Neoplasms+5 more
Okayama University 23
Not applicableStudy completedNCT05750719
What this trial is testing

BRCA and NACT in TNBC Patients

Who this might be right for
Triple-Negative Breast Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 136
Not applicableUnknownNCT04368442
What this trial is testing

Cohort Study of Patients With HER2-negative MBC and BRCA 1/2 Pathogenic Mutation

Who this might be right for
Breast Cancer Metastatic
Samsung Medical Center 583
Testing effectiveness (Phase 2)Study completedNCT04240106
What this trial is testing

Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-,ER+) and gBRCA or HDR+ Metastatic Breast Cancer (LUZERN)

Who this might be right for
Breast CancerBreast Cancer Metastatic
MedSIR 14
Not applicableActive Not RecruitingNCT01990521
What this trial is testing

Prostate Screening Study Using MRI in BRCA Carriers

Who this might be right for
Prostate Cancer
Toronto Sunnybrook Regional Cancer Centre 60
Testing effectiveness (Phase 2)Study completedNCT02983799
What this trial is testing

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Who this might be right for
Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
AstraZeneca 272
Testing effectiveness (Phase 2)Study completedNCT03025035
What this trial is testing

Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer

Who this might be right for
Breast Cancer
Yuan Yuan 14
Not applicableActive Not RecruitingNCT02462460
What this trial is testing

Rapid Pancreatic and Ovarian Screening MR Imaging With Motion Corrected T1, T2, and Advanced Diffusion Weighted Imaging for Patients With BRCA Mutation Who Undergo Screening Breast MRI

Who this might be right for
Screening Breast MRI in Patients Who Are BRCA Mutation Carriers
Memorial Sloan Kettering Cancer Center 63
Large-scale testing (Phase 3)Study completedNCT03402841
What this trial is testing

Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed Non gBRCAm Ovarian Cancer Patients

Who this might be right for
Non-Germline BRCA Mutated Ovarian Cancer
AstraZeneca 279
Large-scale testing (Phase 3)Looking for participantsNCT06952803
What this trial is testing

Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Who this might be right for
Prostate Cancer
AstraZeneca 700
Testing effectiveness (Phase 2)Study completedNCT02282345
What this trial is testing

Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer

Who this might be right for
Breast AdenocarcinomaDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+2 more
M.D. Anderson Cancer Center 36
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