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Results for “BRCA Mutated”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04711109
What this trial is testing

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation

Who this might be right for
BRCA1 MutationBreast CancerBreast Diseases+3 more
Alliance for Clinical Trials in Oncology 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT06380660
What this trial is testing

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultBRCA1 MutationBRCA2 Mutation+3 more
Acerand Therapeutics (Shanghai) Limited 298
Testing effectiveness (Phase 2)Ended earlyNCT02034916
What this trial is testing

A Phase 2, 2-Stage, 2-Cohort Study of Talazoparib (BMN 673), in Locally Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (ABRAZO Study)

Who this might be right for
Breast NeoplasmsBRCA 1 Gene MutationBRCA 2 Gene Mutation
Pfizer 84
Not applicableStudy completedNCT02154633
What this trial is testing

Lessons Learned From the Family Gene Toolkit

Who this might be right for
Women With BRCA 1 or BRCA 2 MutationNon-tested Female Family Members
University of Michigan 13
Not applicableStudy completedNCT04889404
What this trial is testing

LYNPARZA Pancreas Cancer Japan Post-Marketing Surveillance (PMS)

Who this might be right for
Pancreatic Neoplasms
AstraZeneca 130
Not applicableNot Yet RecruitingNCT07764744
What this trial is testing

Ovarian Cancer Liquid Biopsy for Early Assessment & Detection in Individuals With BRCA1/2 Pathogenic Variants

Who this might be right for
Ovarian NeoplasmsBRCA 1 Gene MutationBRCA 2 Gene Mutation+2 more
Weill Medical College of Cornell University 70
Testing effectiveness (Phase 2)Study completedNCT02983799
What this trial is testing

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Who this might be right for
Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
AstraZeneca 272
Testing effectiveness (Phase 2)Active Not RecruitingNCT02393794
What this trial is testing

Cisplatin Plus Romidepsin & Nivolumab in Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Triple-Negative Breast CancerBreast Cancer
Priyanka Sharma 51
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Not applicableStudy completedNCT03066856
What this trial is testing

Dietary Intervention and BRCA Penetrance

Who this might be right for
Dietary ModificationBRCA1 MutationBRCA2 Mutation+1 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 502
Not applicableActive Not RecruitingNCT01990521
What this trial is testing

Prostate Screening Study Using MRI in BRCA Carriers

Who this might be right for
Prostate Cancer
Toronto Sunnybrook Regional Cancer Centre 60
Large-scale testing (Phase 3)Ended earlyNCT04729387
What this trial is testing

Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

Who this might be right for
Ovarian Cancer
Novartis Pharmaceuticals 358
Early research (Phase 1)UnknownNCT02225015
What this trial is testing

Cancer Prevention in Women With a BRCA Mutation

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationBreast Cancer+1 more
Women's College Hospital 300
Not applicableLooking for participantsNCT02306096
What this trial is testing

Sweden Cancerome Analysis Network - Breast : Genomic Profiling of Breast Cancer

Who this might be right for
Breast Neoplasms
Lund University 20,000
Not applicableActive Not RecruitingNCT03351803
What this trial is testing

BRCA Founder OutReach (BFOR) Study

Who this might be right for
BRCA1 MutationBRCA2 Mutation
Memorial Sloan Kettering Cancer Center 5,412
Not applicableStudy completedNCT05775549
What this trial is testing

Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer

Who this might be right for
Advanced Ovarian Cancer
AstraZeneca 24
Testing effectiveness (Phase 2)Study completedNCT01506609
What this trial is testing

Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 294
Not applicableNot Yet RecruitingNCT07736300
What this trial is testing

Epigenomic and Transcriptomic Analysis in BRCA Mutated Carriers With and Without Serous Tubal Intraepithelial Carcinoma

Who this might be right for
EpigenomicsTranscriptomicsBRCA Mutations
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 30
Not applicableNot Yet RecruitingNCT06860217
What this trial is testing

Robotic Nipple Sparing Mastectomy with Immediate Reconstruction

Who this might be right for
Breast CancerDCISBRCA Mutation
European Institute of Oncology 24
Early research (Phase 1)Not Yet RecruitingNCT07088588
What this trial is testing

Study of SYN608 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid CancerMetastatic Solid TumorOvarian Cancer+3 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd 105
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